A small-molecule benzimidazole derivative that potently activates AMPK to increase glucose transport in skeletal muscle: comparison with effects of contraction and other AMPK activators

Phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) is an AMPK target participating in contraction-stimulated glucose uptake in skeletal muscle

(2013) Yang Liu et al.   BIOCHEMICAL JOURNAL

Mammalian target of rapamycin-independent S6K1 and 4E-BP1 phosphorylation during contraction in rat skeletal muscle

(2013) Yang Liu et al.   CELLULAR SIGNALLING

Molecular mechanism of action of metformin: old or new insights?

(2013) Graham Rena et al.   DIABETOLOGIA

Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin

(2013) Morgan D Fullerton et al.   NATURE MEDICINE

Activation of AMP-Activated Protein Kinase Revealed by Hydrogen/Deuterium Exchange Mass Spectrometry

(2013) Rachelle R. Landgraf et al.   STRUCTURE

A novel PKB/Akt inhibitor, MK-2206, effectively inhibits insulin-stimulated glucose metabolism and protein synthesis in isolated rat skeletal muscle

(2012) Yu-Chiang Lai et al.   BIOCHEMICAL JOURNAL

Direct AMP-activated protein kinase activators: a review of evidence from the patent literature

(2012) Fabrizio Giordanetto et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

AMPK: a nutrient and energy sensor that maintains energy homeostasis

(2012) D. Grahame Hardie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

AMP-activated protein kinase (AMPK)  1 2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise

(2011) H. M. O'Neill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of Skeletal Muscle Glycogen Breakdown for Regulation of Insulin Sensitivity by Exercise

(2011) Jørgen Jensen et al.   Frontiers in Physiology

Coordinated maintenance of muscle cell size control by AMP-activated protein kinase

(2010) Louise Lantier et al.   FASEB JOURNAL

Additive effect of contraction and insulin on glucose uptake and glycogen synthase in muscle with different glycogen contents

(2010) Yu-Chiang Lai et al.   JOURNAL OF APPLIED PHYSIOLOGY

Whole Body Deletion of AMP-activated Protein Kinase β2 Reduces Muscle AMPK Activity and Exercise Capacity

(2010) Gregory R. Steinberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin-stimulated glycogen synthesis and glycogen synthase activation after electrical stimulation of epitrochlearis muscles with different initial glycogen contents

(2010) Yu-Chiang Lai et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Glycogen content regulates insulin- but not contraction-mediated glycogen synthase activation in the rat slow-twitch soleus muscles

(2009) Y.-C. Lai et al.   Acta Physiologica

A-769662 activates AMPK β1-containing complexes but induces glucose uptake through a PI3-kinase-dependent pathway in mouse skeletal muscle

(2009) Jonas T. Treebak et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Blunting of AICAR-induced human skeletal muscle glucose uptake in type 2 diabetes is dependent on age rather than diabetic status

(2009) John Andree Babraj et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Inhibition of Contraction-Stimulated AMP-Activated Protein Kinase Inhibits Contraction-Stimulated Increases in PAS-TBC1D1 and Glucose Transport Without Altering PAS-AS160 in Rat Skeletal Muscle

(2009) K. Funai et al.   DIABETES

Skeletal Muscle AMP-activated Protein Kinase Is Essential for the Metabolic Response to Exercisein Vivo

(2009) Robert S. Lee-Young et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Ca2+-calmodulin-eEF2K-eEF2 signalling cascade, but not AMPK, contributes to the suppression of skeletal muscle protein synthesis during contractions

(2009) Adam J. Rose et al.   JOURNAL OF PHYSIOLOGY-LONDON

AMPK in Health and Disease

(2009) Gregory R. Steinberg et al.   PHYSIOLOGICAL REVIEWS

Thienopyridone Drugs Are Selective Activators of AMP-Activated Protein Kinase β1-Containing Complexes

(2008) John W. Scott et al.   CHEMISTRY & BIOLOGY

Discovery of TBC1D1 as an Insulin-, AICAR-, and Contraction-stimulated Signaling Nexus in Mouse Skeletal Muscle

(2008) Eric B. Taylor et al.   JOURNAL OF BIOLOGICAL CHEMISTRY