Synthetic retinoid Am80 up-regulates apelin expression by promoting interaction of RARα with KLF5 and Sp1 in vascular smooth muscle cells

TGF-β1 Downregulates AT1 Receptor Expression via PKC-δ-Mediated Sp1 Dissociation From KLF4 and Smad-Mediated PPAR-γ Association With KLF4

(2012) Xin-hua Zhang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Retinoic Acid Receptor α Mediates All-trans-retinoic Acid-inducedKlf4Gene Expression by RegulatingKlf4Promoter Activity in Vascular Smooth Muscle Cells

(2012) Jian-hong Shi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

KLF5 and hhLIM cooperatively promote proliferation of vascular smooth muscle cells

(2012) Hui-jing Shi et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Cardiovascular effects of a PEGylated apelin

(2012) Z.Q. Jia et al.   PEPTIDES

Overexpression of Angiopoietin-1 Increases CD133+/c-kit+ Cells and Reduces Myocardial Apoptosis in db/db Mouse Infarcted Hearts

(2012) Heng Zeng et al.   PLoS One

Disruption of the Apelin-APJ System Worsens Hypoxia-Induced Pulmonary Hypertension

(2011) Suparna M. Chandra et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

ATRA activates and PDGF-BB represses the SM22α promoter through KLF4 binding to, or dissociating from, its cis-DNA elements

(2011) Kun Yu et al.   CARDIOVASCULAR RESEARCH

HDAC2 phosphorylation-dependent Klf5 deacetylation and RARα acetylation induced by RAR agonist switch the transcription regulatory programs of p21 in VSMCs

(2011) Bin Zheng et al.   CELL RESEARCH

Apelin induces enlarged and nonleaky blood vessels for functional recovery from ischemia

(2010) H. Kidoya et al.   BLOOD

Upregulation of the apelin–APJ pathway promotes neointima formation in the carotid ligation model in mouse

(2010) Yoko Kojima et al.   CARDIOVASCULAR RESEARCH

Interactive Roles of Ets-1, Sp1, and Acetylated Histones in the Retinoic Acid-dependent Activation of Guanylyl Cyclase/Atrial Natriuretic Peptide Receptor-A Gene Transcription

(2010) Prerna Kumar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Krüppel-like Factor 4 Promotes Differentiation by Transforming Growth Factor-β Receptor-mediated Smad and p38 MAPK Signaling in Vascular Smooth Muscle Cells

(2010) Hui-xuan Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Apelin decreases myocardial injury and improves right ventricular function in monocrotaline-induced pulmonary hypertension

(2009) Inês Falcão-Pires et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

All-trans retinoic acid increases KLF4 acetylation by inducing HDAC2 phosphorylation and its dissociation from KLF4 in vascular smooth muscle cells

(2009) Fang Meng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Synthetic retinoid Am80 inhibits interaction of KLF5 with RARα through inducing KLF5 dephosphorylation mediated by the PI3K/Akt signaling in vascular smooth muscle cells

(2009) Xin-hua Zhang et al.   FEBS LETTERS

[Pyr 1 ]Apelin-13 Identified as the Predominant Apelin Isoform in the Human Heart

(2009) Janet J. Maguire et al.   HYPERTENSION

Angiotensin II Stimulates KLF5 Phosphorylation and its Interaction with c-Jun Leading to Suppression of p21 Expression in Vascular Smooth Muscle Cells

(2009) M. He et al.   JOURNAL OF BIOCHEMISTRY

Regulation of the Hyaluronan Synthase 2 Gene by Convergence in Cyclic AMP Response Element-binding Protein and Retinoid Acid Receptor Signaling

(2009) Katri M. Makkonen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Retardation of Retinal Vascular Development in Apelin-Deficient Mice

(2008) Atsushi Kasai et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Hypoxia-Induced Apelin Expression Regulates Endothelial Cell Proliferation and Regenerative Angiogenesis

(2008) Mélanie Eyries et al.   CIRCULATION RESEARCH

Kruppel-like Factor 4 is Required for the Expression of Vascular Smooth Muscle Cell Differentiation Marker Genes Induced by All-Trans Retinoic Acid

(2008) C. Wang et al.   JOURNAL OF BIOCHEMISTRY