Entamoeba histolytica: identification of thioredoxin-targeted proteins and analysis of serine acetyltransferase-1 as a prototype example

Down-regulation of flavin reductase and alcohol dehydrogenase-1 (ADH1) in metronidazole-resistant isolates of Trichomonas vaginalis

(2012) David Leitsch et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

A high-throughput drug screen for Entamoeba histolytica identifies a new lead and target

(2012) Anjan Debnath et al.   NATURE MEDICINE

Disrupted intracellular redox balance of the diplomonad fish parasite Spironucleus vortens by 5-nitroimidazoles and garlic-derived compounds

(2012) C.F. Williams et al.   VETERINARY PARASITOLOGY

Study of the Thiol/Disulfide Redox Systems of the AnaerobeDesulfovibrio vulgarisPoints Out Pyruvate:Ferredoxin Oxidoreductase as a New Target for Thioredoxin 1

(2011) Laetitia Pieulle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural and Biochemical Studies of Serine Acetyltransferase Reveal Why the ParasiteEntamoeba histolyticaCannot Form a Cysteine Synthase Complex

(2011) Sudhir Kumar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of plant cytosolic aldolase functions by redox-modifications

(2011) Karina van der Linde et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Pyruvate:ferredoxin oxidoreductase and bifunctional aldehyde-alcohol dehydrogenase are essential for energy metabolism under oxidative stress in Entamoeba histolytica

(2010) Erika Pineda et al.   FEBS Journal

Metabolome Analysis Revealed Increase inS-Methylcysteine and Phosphatidylisopropanolamine Synthesis upon l-Cysteine Deprivation in the Anaerobic Protozoan ParasiteEntamoeba histolytica

(2010) Afzal Husain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Two Atypical l-Cysteine-regulated NADPH-dependent Oxidoreductases Involved in Redox Maintenance, l-Cystine and Iron Reduction, and Metronidazole Activation in the Enteric ProtozoanEntamoeba histolytica

(2010) Ghulam Jeelani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bacterial-type oxygen detoxification and iron-sulfur cluster assembly in amoebal relict mitochondria

(2009) Barbora Maralikova et al.   CELLULAR MICROBIOLOGY

Regulation of Translation by the Redox State of Elongation Factor G in the CyanobacteriumSynechocystissp. PCC 6803

(2009) Kouji Kojima et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Trichomonas vaginalis: metronidazole and other nitroimidazole drugs are reduced by the flavin enzyme thioredoxin reductase and disrupt the cellular redox system. Implications for nitroimidazole toxicity and resistance

(2009) David Leitsch et al.   MOLECULAR MICROBIOLOGY

Identification of Proteins Targeted by the Thioredoxin Superfamily in Plasmodium falciparum

(2009) Nicole Sturm et al.   PLoS Pathogens

Entamoeba histolytica: Response of the parasite to metronidazole challenge on the levels of mRNA and protein expression

(2008) Margit Tazreiter et al.   EXPERIMENTAL PARASITOLOGY

Immunolocalization and enzymatic functional characterization of the thioredoxin system in Entamoeba histolytica

(2008) Diego G. Arias et al.   FREE RADICAL BIOLOGY AND MEDICINE

Isoform-dependent feedback regulation of serine O-acetyltransferase isoenzymes involved in l-cysteine biosynthesis of Entamoeba histolytica

(2008) Sarwar Hussain et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Crystal structure of native O-acetyl-serine sulfhydrylase from Entamoeba histolytica and its complex with cysteine: Structural evidence for cysteine binding and lack of interactions with serine acetyl transferase

(2008) Krishna Chinthalapudi et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

In silico identification of the protein disulfide isomerase family from a protozoan parasite

(2007) Marco A. Ramos et al.   COMPUTATIONAL BIOLOGY AND CHEMISTRY