Polyamine production is downstream and upstream of oncogenic PI3K signalling and contributes to tumour cell growth

Phosphoproteomic Analysis of Leukemia Cells under Basal and Drug-treated Conditions Identifies Markers of Kinase Pathway Activation and Mechanisms of Resistance

(2012) Maria P. Alcolea et al.   MOLECULAR & CELLULAR PROTEOMICS

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Characterization of a TiO2 enrichment method for label-free quantitative phosphoproteomics

(2011) Alex Montoya et al.   METHODS

P21-activated kinase 1 stimulates colon cancer cell growth and migration/invasion via ERK- and AKT-dependent pathways

(2010) Nhi Huynh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Receptor Tyrosine Kinase Coactivation Networks in Cancer

(2010) A. M. Xu et al.   CANCER RESEARCH

The Role of Polyamines in Supporting Growth of Mammalian Cells Is Mediated through Their Requirement for Translation Initiation and Elongation

(2010) Guy Landau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The emerging mechanisms of isoform-specific PI3K signalling

(2010) Bart Vanhaesebroeck et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

mTOR: from growth signal integration to cancer, diabetes and ageing

(2010) Roberto Zoncu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Polar Anionic Metabolome Analysis by Nano-LC/MS with a Metal Chelating Agent

(2009) Khin Than Myint et al.   ANALYTICAL CHEMISTRY

The polyamines regulate endothelial cell survival during hypoxic stress through PI3K/AKT and MCL-1

(2009) Paulina Kucharzewska et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mice Heterozygous for Germ-line Mutations in Methylthioadenosine Phosphorylase (MTAP) Die Prematurely of T-Cell Lymphoma

(2009) Y. Kadariya et al.   CANCER RESEARCH

Targeting the PI3K signaling pathway in cancer

(2009) Kwok-Kin Wong et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

PAK signaling in oncogenesis

(2009) P R Molli et al.   ONCOGENE

Ornithine Decarboxylase Inhibition by  -Difluoromethylornithine Activates Opposing Signaling Pathways via Phosphorylation of Both Akt/Protein Kinase B and p27Kip1 in Neuroblastoma

(2008) D.-L. T. Koomoa et al.   CANCER RESEARCH

The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation

(2008) Ralph J. DeBerardinis et al.   Cell Metabolism

Molecular and Morphological Changes in Placenta and Embryo Development Associated with the Inhibition of Polyamine Synthesis during Midpregnancy in Mice

(2008) Carlos López-García et al.   ENDOCRINOLOGY

Angiogenesis selectively requires the p110α isoform of PI3K to control endothelial cell migration

(2008) Mariona Graupera et al.   NATURE

The role of PTEN signaling perturbations in cancer and in targeted therapy

(2008) M Keniry et al.   ONCOGENE