Both p110α and p110β isoforms of PI3K can modulate the impact of loss-of-function of the PTEN tumour suppressor
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Title
Both p110α and p110β isoforms of PI3K can modulate the impact of loss-of-function of the PTEN tumour suppressor
Authors
Keywords
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Journal
BIOCHEMICAL JOURNAL
Volume 442, Issue 1, Pages 151-159
Publisher
Portland Press Ltd.
Online
2011-12-08
DOI
10.1042/bj20111741
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Related references
Note: Only part of the references are listed.- PDK1 Attenuation Fails to Prevent Tumor Formation in PTEN-Deficient Transgenic Mouse Models
- (2011) K. Ellwood-Yen et al. CANCER RESEARCH
- Nuclear PTEN Regulates the APC-CDH1 Tumor-Suppressive Complex in a Phosphatase-Independent Manner
- (2011) Min Sup Song et al. CELL
- Quantification of PtdInsP3 molecular species in cells and tissues by mass spectrometry
- (2011) Jonathan Clark et al. NATURE METHODS
- Phosphoinositide 3-Kinase Pathway Activation in Phosphate and Tensin Homolog (PTEN)-deficient Prostate Cancer Cells Is Independent of Receptor Tyrosine Kinases and Mediated by the p110β and p110δ Catalytic Subunits
- (2010) Xinnong Jiang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The emerging mechanisms of isoform-specific PI3K signalling
- (2010) Bart Vanhaesebroeck et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Activity of any class IA PI3K isoform can sustain cell proliferation and survival
- (2010) L. C. Foukas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- mTOR Complex 2 Is Required for the Development of Prostate Cancer Induced by Pten Loss in Mice
- (2009) David A. Guertin et al. CANCER CELL
- AKT-Independent Signaling Downstream of Oncogenic PIK3CA Mutations in Human Cancer
- (2009) Krishna M. Vasudevan et al. CANCER CELL
- A chemical screen in diverse breast cancer cell lines reveals genetic enhancers and suppressors of sensitivity to PI3K isoform-selective inhibition
- (2008) Neil E. Torbett et al. BIOCHEMICAL JOURNAL
- Important role of the LKB1–AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice
- (2008) Xu Huang et al. BIOCHEMICAL JOURNAL
- The Protein Phosphatase Activity of PTEN Regulates Src Family Kinases and Controls Glioma Migration
- (2008) N. Dey et al. CANCER RESEARCH
- PIK3CA Cooperates with Other Phosphatidylinositol 3'-Kinase Pathway Mutations to Effect Oncogenic Transformation
- (2008) K. Oda et al. CANCER RESEARCH
- Distinct roles of class IA PI3K isoforms in primary and immortalised macrophages
- (2008) E. A. Papakonstanti et al. JOURNAL OF CELL SCIENCE
- The p110 isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110
- (2008) J. Guillermet-Guibert et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PTEN-deficient cancers depend on PIK3CB
- (2008) S. Wee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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