Activity of any class IA PI3K isoform can sustain cell proliferation and survival
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Title
Activity of any class IA PI3K isoform can sustain cell proliferation and survival
Authors
Keywords
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 107, Issue 25, Pages 11381-11386
Publisher
Proceedings of the National Academy of Sciences
Online
2010-06-08
DOI
10.1073/pnas.0906461107
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Note: Only part of the references are listed.- Molecular pharmacology of phosphatidylinositol 3-kinase inhibition in human glioma
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- Targeting the Phosphoinositide 3-Kinase Isoform p110 Impairs Growth and Survival in Neuroblastoma Cells
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- Enhanced anti-cancer effect of a phosphatidylinositol-3 kinase inhibitor and doxorubicin on human breast epithelial cell lines with different p53 and oestrogen receptor status
- (2008) Yan A. Wang et al. INTERNATIONAL JOURNAL OF CANCER
- Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents
- (2008) Michael Degtyarev et al. JOURNAL OF CELL BIOLOGY
- Distinct roles of class IA PI3K isoforms in primary and immortalised macrophages
- (2008) E. A. Papakonstanti et al. JOURNAL OF CELL SCIENCE
- Phosphoinositide 3-Kinases p110 and p110 Regulate Cell Cycle Entry, Exhibiting Distinct Activation Kinetics in G1 Phase
- (2008) M. Marques et al. MOLECULAR AND CELLULAR BIOLOGY
- Angiogenesis selectively requires the p110α isoform of PI3K to control endothelial cell migration
- (2008) Mariona Graupera et al. NATURE
- Of lineage and legacy: the development of mammalian hematopoietic stem cells
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- Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers
- (2008) Jeffrey A Engelman et al. NATURE MEDICINE
- Phosphoinositide 3-OH kinase p85α and p110β are essential for androgen receptor transactivation and tumor progression in prostate cancers
- (2008) Q Zhu et al. ONCOGENE
- PI3K pathway alterations in cancer: variations on a theme
- (2008) T L Yuan et al. ONCOGENE
- The p110 isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110
- (2008) J. Guillermet-Guibert et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2008) S. Wee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phosphoinositide 3-Kinase p110 Activity: Key Role in Metabolism and Mammary Gland Cancer but Not Development
- (2008) E. Ciraolo et al. Science Signaling
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