ER stress modulates cellular metabolism

ER stress negatively regulates AKT/TSC/mTOR pathway to enhance autophagy

(2010) Liang Qin et al.   Autophagy

Actinomycin D synergistically enhances the efficacy of the BH3 mimetic ABT-737 by downregulating Mcl-1 expression

(2010) Kristen E. Olberding et al.   CANCER BIOLOGY & THERAPY

The ER UDPase ENTPD5 Promotes Protein N-Glycosylation, the Warburg Effect, and Proliferation in the PTEN Pathway

(2010) Min Fang et al.   CELL

Bcl-2 proteins regulate ER membrane permeability to luminal proteins during ER stress-induced apoptosis

(2010) X Wang et al.   CELL DEATH AND DIFFERENTIATION

The critical role of GRP78 in physiologic and pathologic stress

(2010) Kyle T Pfaffenbach et al.   CURRENT OPINION IN CELL BIOLOGY

Akt is the downstream target of GRP78 in mediating cisplatin resistance in ER stress-tolerant human lung cancer cells

(2010) Yidan Lin et al.   LUNG CANCER

Regulation Mechanisms and Signaling Pathways of Autophagy

(2009) Congcong He et al.   Annual Review of Genetics

Altered regulation of metabolic pathways in human lung cancer discerned by 13C stable isotope-resolved metabolomics (SIRM)

(2009) Teresa WM Fan et al.   Molecular Cancer

An essential role for the Glut1 PDZ-binding motif in growth factor regulation of Glut1 degradation and trafficking

(2008) Heather L. Wieman et al.   BIOCHEMICAL JOURNAL

The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells

(2008) J Li et al.   CELL DEATH AND DIFFERENTIATION

Stable isotope-assisted metabolomics in cancer research

(2008) Andrew N. Lane et al.   IUBMB LIFE

Glucose metabolism in lymphocytes is a regulated process with significant effects on immune cell function and survival

(2008) Nancie J. MacIver et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Autophagy Provides Nutrients but Can Lead to Chop-dependent Induction of Bim to Sensitize Growth Factor–deprived Cells to Apoptosis

(2008) Brian J. Altman et al.   MOLECULAR BIOLOGY OF THE CELL

Rhabdomyosarcoma cells show an energy producing anabolic metabolic phenotype compared with primary myocytes

(2008) Teresa WM Fan et al.   Molecular Cancer

Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities

(2008) Inki Kim et al.   NATURE REVIEWS DRUG DISCOVERY

The endoplasmic reticulum in apoptosis and autophagy: role of the BCL-2 protein family

(2008) H M Heath-Engel et al.   ONCOGENE