Novel regulation of PLCζ activity via its XY-linker

Male infertility-linked point mutation disrupts the Ca2+oscillation-inducing and PIP2hydrolysis activity of sperm PLCζ

(2011) Michail Nomikos et al.   BIOCHEMICAL JOURNAL

Phospholipase C  binding to PtdIns(4,5)P2 requires the XY-linker region

(2011) M. Nomikos et al.   JOURNAL OF CELL SCIENCE

Mechanism of Phosphorylation-induced Activation of Phospholipase C-γ Isozymes

(2010) Aurelie Gresset et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PLC regulation: emerging pictures for molecular mechanisms

(2010) Tom D. Bunney et al.   TRENDS IN BIOCHEMICAL SCIENCES

Human sperm devoid of PLC, zeta 1 fail to induce Ca2+ release and are unable to initiate the first step of embryo development

(2008) Sook-Young Yoon et al.   JOURNAL OF CLINICAL INVESTIGATION

General and Versatile Autoinhibition of PLC Isozymes

(2008) Stephanie N. Hicks et al.   MOLECULAR CELL