Kinetic Investigations of the Role of Factor Inhibiting Hypoxia-inducible Factor (FIH) as an Oxygen Sensor
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Kinetic Investigations of the Role of Factor Inhibiting Hypoxia-inducible Factor (FIH) as an Oxygen Sensor
Authors
Keywords
-
Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 290, Issue 32, Pages 19726-19742
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2015-06-26
DOI
10.1074/jbc.m115.653014
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Investigating the contribution of the active site environment to the slow reaction of hypoxia-inducible factor prolyl hydroxylase domain 2 with oxygen
- (2014) Hanna Tarhonskaya et al. BIOCHEMICAL JOURNAL
- Studies on Deacetoxycephalosporin C Synthase Support a Consensus Mechanism for 2-Oxoglutarate Dependent Oxygenases
- (2014) Hanna Tarhonskaya et al. BIOCHEMISTRY
- Oxygen-dependent hydroxylation by FIH regulates the TRPV3 ion channel
- (2014) S. Karttunen et al. JOURNAL OF CELL SCIENCE
- Oxygen sensing and metabolic homeostasis
- (2014) Biff F. Palmer et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Human oxygen sensing may have origins in prokaryotic elongation factor Tu prolyl-hydroxylation
- (2014) John S. Scotti et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Non-enzymatic chemistry enables 2-hydroxyglutarate-mediated activation of 2-oxoglutarate oxygenases
- (2014) Hanna Tarhonskaya et al. Nature Communications
- Substrate Selectivity Analyses of Factor Inhibiting Hypoxia-Inducible Factor
- (2013) Ming Yang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Overexpression of gankyrin in mouse hepatocytes induces hemangioma by suppressing factor inhibiting hypoxia-inducible factor-1 (FIH-1) and activating hypoxia-inducible factor-1
- (2013) Yu Liu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Inverse Solvent Isotope Effects Arising from Substrate Triggering in the Factor Inhibiting Hypoxia Inducible Factor
- (2013) John A. Hangasky et al. BIOCHEMISTRY
- Substrate preference of the HIF-prolyl hydroxylase-2 (PHD2) and substrate-induced conformational change
- (2013) Serap Pektas et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Inverse Solvent Isotope Effects Demonstrate Slow Aquo Release from Hypoxia Inducible Factor-Prolyl Hydroxylase (PHD2)
- (2012) Shannon C. Flagg et al. BIOCHEMISTRY
- Factor Inhibiting HIF (FIH) Recognizes Distinct Molecular Features within Hypoxia-inducible Factor-α (HIF-α)versusAnkyrin Repeat Substrates
- (2012) Sarah E. Wilkins et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- HIF-1 versus HIF-2 — Is one more important than the other?
- (2012) Agnieszka Loboda et al. VASCULAR PHARMACOLOGY
- Hypoxia. Cross talk between oxygen sensing and the cell cycle machinery
- (2011) Gregg L. Semenza AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Factor-inhibiting hypoxia-inducible factor (FIH) catalyses the post-translational hydroxylation of histidinyl residues within ankyrin repeat domains
- (2011) Ming Yang et al. FEBS Journal
- Differential Sensitivity of Hypoxia Inducible Factor Hydroxylation Sites to Hypoxia and Hydroxylase Inhibitors
- (2011) Ya-Min Tian et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hypoxia-dependent sequestration of an oxygen sensor by a widespread structural motif can shape the hypoxic response - a predictive kinetic model
- (2010) Bernhard Schmierer et al. BMC Systems Biology
- Evidence for the slow reaction of hypoxia-inducible factor prolyl hydroxylase 2 with oxygen
- (2010) Emily Flashman et al. FEBS Journal
- Physiological and biochemical aspects of hydroxylations and demethylations catalyzed by human 2-oxoglutarate oxygenases
- (2010) Christoph Loenarz et al. TRENDS IN BIOCHEMICAL SCIENCES
- Evidence for a Stereoelectronic Effect in Human Oxygen Sensing
- (2009) Christoph Loenarz et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- FIH-Dependent Asparaginyl Hydroxylation of Ankyrin Repeat Domain-Containing Proteins
- (2009) Matthew E. Cockman et al. Annals of the New York Academy of Sciences
- MYPT1, the targeting subunit of smooth-muscle myosin phosphatase, is a substrate for the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH)
- (2009) James D. Webb et al. BIOCHEMICAL JOURNAL
- Substrate-Triggered Formation and Remarkable Stability of the C−H Bond-Cleaving Chloroferryl Intermediate in the Aliphatic Halogenase, SyrB2
- (2009) Megan L. Matthews et al. BIOCHEMISTRY
- Hypoxia, hypoxia-inducible factors (HIF), HIF hydroxylases and oxygen sensing
- (2009) James D. Webb et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Differences in hydroxylation and binding of Notch and HIF-1α demonstrate substrate selectivity for factor inhibiting HIF-1 (FIH-1)
- (2009) Sarah E. Wilkins et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Asparaginyl β-Hydroxylation of Proteins Containing Ankyrin Repeat Domains Influences Their Stability and Function
- (2009) Adam P. Hardy et al. JOURNAL OF MOLECULAR BIOLOGY
- Structural Basis for Binding of Hypoxia-Inducible Factor to the Oxygen-Sensing Prolyl Hydroxylases
- (2009) Rasheduzzaman Chowdhury et al. STRUCTURE
- Kinetic characterization and identification of a novel inhibitor of hypoxia-inducible factor prolyl hydroxylase 2 using a time-resolved fluorescence resonance energy transfer-based assay technology
- (2008) Jennifer H. Dao et al. ANALYTICAL BIOCHEMISTRY
- Asparagine β-hydroxylation stabilizes the ankyrin repeat domain fold
- (2008) Leanne Kelly et al. Molecular BioSystems
- Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
- (2008) William G. Kaelin et al. MOLECULAR CELL
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started