Evidence for the slow reaction of hypoxia-inducible factor prolyl hydroxylase 2 with oxygen

Investigating the dependence of the hypoxia-inducible factor hydroxylases (factor inhibiting HIF and prolyl hydroxylase domain 2) on ascorbate and other reducing agents

(2010) Emily Flashman et al.   BIOCHEMICAL JOURNAL

Substrate-Triggered Formation and Remarkable Stability of the C−H Bond-Cleaving Chloroferryl Intermediate in the Aliphatic Halogenase, SyrB2

(2009) Megan L. Matthews et al.   BIOCHEMISTRY

Using NMR Solvent Water Relaxation to Investigate Metalloenzyme−Ligand Binding Interactions

(2009) Ivanhoe K. H. Leung et al.   JOURNAL OF MEDICINAL CHEMISTRY

Substrate positioning controls the partition between halogenation and hydroxylation in the aliphatic halogenase, SyrB2

(2009) M. L. Matthews et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis for Binding of Hypoxia-Inducible Factor to the Oxygen-Sensing Prolyl Hydroxylases

(2009) Rasheduzzaman Chowdhury et al.   STRUCTURE

Kinetic characterization and identification of a novel inhibitor of hypoxia-inducible factor prolyl hydroxylase 2 using a time-resolved fluorescence resonance energy transfer-based assay technology

(2008) Jennifer H. Dao et al.   ANALYTICAL BIOCHEMISTRY

The human oxygen sensing machinery and its manipulation

(2008) Rasheduzzaman Chowdhury et al.   CHEMICAL SOCIETY REVIEWS

Dynamic states of the DNA repair enzyme AlkB regulate product release

(2008) Boris Bleijlevens et al.   EMBO REPORTS

Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway

(2008) William G. Kaelin et al.   MOLECULAR CELL