Urotensin-II Receptor Stimulation of Cardiac L-type Ca2+Channels Requires the βγ Subunits of Gi/o-protein and Phosphatidylinositol 3-Kinase-dependent Protein Kinase C β1 Isoform

Identification of transmembrane domain 1 & 2 residues that contribute to the formation of the ligand-binding pocket of the urotensin-II receptor

(2014) Xavier Sainsily et al.   BIOCHEMICAL PHARMACOLOGY

Interleukin-1β Reduces L-type Ca2+Current through Protein Kinase Cϵ Activation in Mouse Heart

(2014) Nabil El Khoury et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

L-Type CaV1.2 Calcium Channels: From In Vitro Findings to In Vivo Function

(2014) Franz Hofmann et al.   PHYSIOLOGICAL REVIEWS

The Bcl-2 Homolog Nrz Inhibits Binding of IP3 to Its Receptor to Control Calcium Signaling During Zebrafish Epiboly

(2014) B. Bonneau et al.   Science Signaling

Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNF  in glioblastoma

(2014) Y. Kusne et al.   Science Signaling

AKAP150-dependent cooperative TRPV4 channel gating is central to endothelium-dependent vasodilation and is disrupted in hypertension

(2014) S. K. Sonkusare et al.   Science Signaling

Antagonism of EGFR and HER3 Enhances the Response to Inhibitors of the PI3K-Akt Pathway in Triple-Negative Breast Cancer

(2014) J. J. Tao et al.   Science Signaling

Tumor-Induced STAT3 Signaling in Myeloid Cells Impairs Dendritic Cell Generation by Decreasing PKC II Abundance

(2014) M. R. Farren et al.   Science Signaling

Calmodulin and PI(3,4,5)P3 cooperatively bind to the Itk pleckstrin homology domain to promote efficient calcium signaling and IL-17A production

(2014) X. Wang et al.   Science Signaling

Mechanochemotransduction During Cardiomyocyte Contraction Is Mediated by Localized Nitric Oxide Signaling

(2014) Z. Jian et al.   Science Signaling

L-type calcium channel targeting and local signalling in cardiac myocytes

(2013) Robin M. Shaw et al.   CARDIOVASCULAR RESEARCH

Insulin-Like Growth Factor-1 Receptor-Mediated Inhibition of A-type K+Current Induces Sensory Neuronal Hyperexcitability Through the Phosphatidylinositol 3-Kinase and Extracellular Signal-Regulated Kinase 1/2 Pathways, Independently of Akt

(2013) Hua Wang et al.   ENDOCRINOLOGY

PLC-  and PI3K Link Cytokines to ERK Activation in Hematopoietic Cells with Normal and Oncogenic Kras

(2013) E. Diaz-Flores et al.   Science Signaling

Bypass Mechanisms of Resistance to Receptor Tyrosine Kinase Inhibition in Lung Cancer

(2013) M. J. Niederst et al.   Science Signaling

Phosphoinositide 3-Kinase   Inhibits Cardiac GSK-3 Independently of Akt

(2013) M. L. Mohan et al.   Science Signaling

Profiles of Basal and Stimulated Receptor Signaling Networks Predict Drug Response in Breast Cancer Lines

(2013) M. Niepel et al.   Science Signaling

AKT Facilitates EGFR Trafficking and Degradation by Phosphorylating and Activating PIKfyve

(2013) E. E. Er et al.   Science Signaling

Ca2+-Dependent Phosphorylation of Ca2+ Cycling Proteins Generates Robust Rhythmic Local Ca2+ Releases in Cardiac Pacemaker Cells

(2013) S. Sirenko et al.   Science Signaling

Cytokinins Secreted by Agrobacterium Promote Transformation by Repressing a Plant Myb Transcription Factor

(2013) N. Sardesai et al.   Science Signaling

Tyrosine Kinase BMX Phosphorylates Phosphotyrosine-Primed Motif Mediating the Activation of Multiple Receptor Tyrosine Kinases

(2013) S. Chen et al.   Science Signaling

The Transcription Factor CREB Enhances Interleukin-17A Production and Inflammation in a Mouse Model of Atherosclerosis

(2013) S. Kotla et al.   Science Signaling

Neuromedin U Type 1 Receptor Stimulation of A-type K+Current Requires the βγ Subunits of GoProtein, Protein Kinase A, and Extracellular Signal-regulated Kinase 1/2 (ERK1/2) in Sensory Neurons

(2012) Yiming Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of dendritic Ca2+spikes by GABABreceptors in cortical pyramidal neurons is mediated by a direct Gi/o-βγ-subunit interaction with Cav1 channels

(2012) Enrique Pérez-Garci et al.   JOURNAL OF PHYSIOLOGY-LONDON

Altered sarcoplasmic reticulum calcium cycling—targets for heart failure therapy

(2012) Changwon Kho et al.   Nature Reviews Cardiology

Protein Quality Control Disruption by PKCβII in Heart Failure; Rescue by the Selective PKCβII Inhibitor, βIIV5-3

(2012) Julio C. B. Ferreira et al.   PLoS One

Urotensin II, from fish to human

(2010) Hubert Vaudry et al.   Annals of the New York Academy of Sciences

Alternative splicing modulates diltiazem sensitivity of cardiac and vascular smooth muscle Cav1.2 calcium channels

(2010) Heng Yu Zhang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Activation of neuromedin U type 1 receptor inhibits L-type Ca2+ channel currents via phosphatidylinositol 3-kinase-dependent protein kinase C epsilon pathway in mouse hippocampal neurons

(2010) Yuan Zhang et al.   CELLULAR SIGNALLING

L-type channel inhibition by CB1 cannabinoid receptors is mediated by PTX-sensitive G proteins and cAMP/PKA in GT1-7 hypothalamic neurons

(2009) Hanaa Hoddah et al.   CELL CALCIUM

Protein Kinase A Activity Controls the Regulation of T-type CaV3.2 Channels by Gβγ Dimers

(2009) Changlong Hu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of voltage-gated L-type calcium channels by labedipinedilol-A involves protein kinase C in rat cerebrovascular smooth muscle cells

(2009) Bin-Nan Wu et al.   VASCULAR PHARMACOLOGY

New Determinant for the CaVβ2Subunit Modulation of the CaV1.2 Calcium Channel

(2008) Qi Zong Lao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of Corticotropin-Releasing Factor Receptor 1 Selectively Inhibits CaV3.2 T-Type Calcium Channels

(2008) J. Tao et al.   MOLECULAR PHARMACOLOGY

Calcium Cycling and Signaling in Cardiac Myocytes

(2007) Donald M. Bers   Annual Review of Physiology