cGMP/Protein Kinase G Signaling Suppresses Inositol 1,4,5-Trisphosphate Receptor Phosphorylation and Promotes Endoplasmic Reticulum Stress in Photoreceptors of Cyclic Nucleotide-gated Channel-deficient Mice

Mutations in the unfolded protein response regulator ATF6 cause the cone dysfunction disorder achromatopsia

(2015) Susanne Kohl et al.   NATURE GENETICS

Receptor-interacting protein 140 attenuates endoplasmic reticulum stress in neurons and protects against cell death

(2014) Xudong Feng et al.   Nature Communications

Loss of cone cyclic nucleotide-gated channel leads to alterations in light response modulating system and cellular stress response pathways: a gene expression profiling study

(2013) Hongwei Ma et al.   HUMAN MOLECULAR GENETICS

cGMP Accumulation Causes Photoreceptor Degeneration in CNG Channel Deficiency: Evidence of cGMP Cytotoxicity Independently of Enhanced CNG Channel Function

(2013) J. Xu et al.   JOURNAL OF NEUROSCIENCE

Endoplasmic Reticulum Stress-associated Cone Photoreceptor Degeneration in Cyclic Nucleotide-gated Channel Deficiency

(2012) Arjun Thapa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective modulation of subtype III IP3R by Akt regulates ER Ca2+ release and apoptosis

(2012) S Marchi et al.   Cell Death & Disease

Cyclic GMP induced apoptosis via protein kinase G in oestrogen receptor-positive and -negative breast cancer cell lines

(2011) Faranak Fallahian et al.   FEBS Journal

Long-term and age-dependent restoration of visual function in a mouse model of CNGB3-associated achromatopsia following gene therapy

(2011) L. S. Carvalho et al.   HUMAN MOLECULAR GENETICS

Ca2+ store depletion and endoplasmic reticulum stress are involved in P2X7 receptor-mediated neurotoxicity in differentiated NG108-15 cells

(2011) Chia-Chia Chao et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

PKG-mediated MAPK signaling is necessary for long-term operant memory in Aplysia

(2011) M. Michel et al.   LEARNING & MEMORY

Endoplasmic-Reticulum Calcium Depletion and Disease

(2011) D. Mekahli et al.   Cold Spring Harbor Perspectives in Biology

The Disease-Causing Mutations in the Carboxyl Terminus of the Cone Cyclic Nucleotide-Gated Channel CNGA3 Subunit Alter the Local Secondary Structure and Interfere with the Channel Active Conformational Change

(2010) Alexander V. Matveev et al.   BIOCHEMISTRY

A key role for cyclic nucleotide gated (CNG) channels in cGMP-related retinitis pigmentosa

(2010) François Paquet-Durand et al.   HUMAN MOLECULAR GENETICS

shRNA knockdown of guanylate cyclase 2e or cyclic nucleotide gated channel alpha 1 increases photoreceptor survival in a cGMP phosphodiesterase mouse model of retinitis pigmentosa

(2010) Joaquin Tosi et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Restoration of Cone Vision in the CNGA3−/− Mouse Model of Congenital Complete Lack of Cone Photoreceptor Function

(2010) Stylianos Michalakis et al.   MOLECULAR THERAPY

Impaired cone function and cone degeneration resulting from CNGB3 deficiency: down-regulation of CNGA3 biosynthesis as a potential mechanism

(2009) X.-Q. Ding et al.   HUMAN MOLECULAR GENETICS

Roles of IP3R and RyR Ca2+ Channels in Endoplasmic Reticulum Stress and  -Cell Death

(2008) D. S. Luciani et al.   DIABETES

PKG activity causes photoreceptor cell death in two retinitis pigmentosa models

(2008) François Paquet-Durand et al.   JOURNAL OF NEUROCHEMISTRY

Depletion of calcium stores regulates calcium influx and signal transmission in rod photoreceptors

(2008) Tamas Szikra et al.   JOURNAL OF PHYSIOLOGY-LONDON

Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities

(2008) Inki Kim et al.   NATURE REVIEWS DRUG DISCOVERY

Phosphorylation of inositol 1,4,5-trisphosphate receptors by protein kinase B/Akt inhibits Ca2+ release and apoptosis

(2008) T. Szado et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA