Histone Deacetylase Inhibitors Target the Leukemic Microenvironment by Enhancing a Nherf1-Protein Phosphatase 1α-TAZ Signaling Pathway in Osteoblasts
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Title
Histone Deacetylase Inhibitors Target the Leukemic Microenvironment by Enhancing a Nherf1-Protein Phosphatase 1α-TAZ Signaling Pathway in Osteoblasts
Authors
Keywords
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Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 290, Issue 49, Pages 29478-29492
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2015-10-22
DOI
10.1074/jbc.m115.668160
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Note: Only part of the references are listed.- Advances in understanding the leukaemia microenvironment
- (2014) Yoko Tabe et al. BRITISH JOURNAL OF HAEMATOLOGY
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- (2014) Mark Kirschbaum et al. BRITISH JOURNAL OF HAEMATOLOGY
- Canonical Wnt signalling activates TAZ through PP1A during osteogenic differentiation
- (2014) M R Byun et al. CELL DEATH AND DIFFERENTIATION
- The Hippo pathway effectors TAZ and YAP in development, homeostasis and disease
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- (−)-Epicatechin Gallate (ECG) Stimulates Osteoblast Differentiation via Runt-related Transcription Factor 2 (RUNX2) and Transcriptional Coactivator with PDZ-binding Motif (TAZ)-mediated Transcriptional Activation
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- Histone Deacetylase Inhibition Destabilizes the Multi-Potent State of Uncommitted Adipose-Derived Mesenchymal Stromal Cells
- (2014) Amel Dudakovic et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Leukaemogenesis induced by an activating β-catenin mutation in osteoblasts
- (2014) Aruna Kode et al. NATURE
- The Biology of YAP/TAZ: Hippo Signaling and Beyond
- (2014) Stefano Piccolo et al. PHYSIOLOGICAL REVIEWS
- Translational Phase I Trial of Vorinostat (Suberoylanilide Hydroxamic Acid) Combined with Cytarabine and Etoposide in Patients with Relapsed, Refractory, or High-Risk Acute Myeloid Leukemia
- (2013) I. Gojo et al. CLINICAL CANCER RESEARCH
- CXCR4 Chemokine Receptor Signaling Induces Apoptosis in Acute Myeloid Leukemia Cells via Regulation of the Bcl-2 Family Members Bcl-XL, Noxa, and Bak
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- (2013) Amel Dudakovic et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Osteoblasts Protect AML Cells From SDF-1-Induced Apoptosis
- (2013) Kimberly N. Kremer et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Differential regulation of myeloid leukemias by the bone marrow microenvironment
- (2013) Daniela S Krause et al. NATURE MEDICINE
- The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment
- (2013) Randy Johnson et al. NATURE REVIEWS DRUG DISCOVERY
- Vorinostat Induces Apoptosis and Differentiation in Myeloid Malignancies: Genetic and Molecular Mechanisms
- (2013) Gabriela Silva et al. PLoS One
- Ajuba Family Proteins Link JNK to Hippo Signaling
- (2013) G. Sun et al. Science Signaling
- Can we improve outcomes in patients with acute myelogenous leukemia? Incorporating HDAC inhibitors into front-line therapy
- (2012) Guillermo Garcia-Manero BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY
- Regulation of protein phosphatase 1 by intrinsically disordered proteins
- (2012) Meng S. Choy et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Osteopontin is a prognostic factor for survival of acute myeloid leukemia patients
- (2012) R. Liersch et al. BLOOD
- Human extramedullary bone marrow in mice: a novel in vivo model of genetically controlled hematopoietic microenvironment
- (2012) Y. Chen et al. BLOOD
- NHERF1 regulation of PTH-dependent bimodal Pi transport in osteoblasts
- (2012) Bin Wang et al. BONE
- Na+/H+Exchanger Regulatory Factor 1 (NHERF1) Directly Regulates Osteogenesis
- (2012) Li Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phase II Trial of Vorinostat With Idarubicin and Cytarabine for Patients With Newly Diagnosed Acute Myelogenous Leukemia or Myelodysplastic Syndrome
- (2012) Guillermo Garcia-Manero et al. JOURNAL OF CLINICAL ONCOLOGY
- p53 activation of mesenchymal stromal cells partially abrogates microenvironment-mediated resistance to FLT3 inhibition in AML through HIF-1 -mediated down-regulation of CXCL12
- (2011) K. Kojima et al. BLOOD
- Suberoylanilide hydroxamic acid (SAHA; vorinostat) causes bone loss by inhibiting immature osteoblasts
- (2011) Meghan E. McGee-Lawrence et al. BONE
- TAZ is required for the osteogenic and anti-adipogenic activities of kaempferol
- (2011) Mi Ran Byun et al. BONE
- Vorinostat Induces Reactive Oxygen Species and DNA Damage in Acute Myeloid Leukemia Cells
- (2011) Luca A. Petruccelli et al. PLoS One
- Vorinostat in acute myeloid leukemia and myelodysplastic syndromes
- (2010) Thomas Prebet et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- PP1 Cooperates with ASPP2 to Dephosphorylate and Activate TAZ
- (2010) Chen-Ying Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia
- (2010) Marc H. G. P. Raaijmakers et al. NATURE
- Therapeutic targeting of microenvironmental interactions in leukemia: Mechanisms and approaches
- (2009) Marina Konopleva et al. DRUG RESISTANCE UPDATES
- Ephrin B1 Regulates Bone Marrow Stromal Cell Differentiation and Bone Formation by Influencing TAZ Transactivation via Complex Formation with NHERF1
- (2009) W. Xing et al. MOLECULAR AND CELLULAR BIOLOGY
- Phase 1 study of the oral isotype specific histone deacetylase inhibitor MGCD0103 in leukemia
- (2008) G. Garcia-Manero et al. BLOOD
- Histone deacetylase inhibitors: Mechanisms of cell death and promise in combination cancer therapy
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- (2008) Q.-Y. Lei et al. MOLECULAR AND CELLULAR BIOLOGY
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