Microglial Heparan Sulfate Proteoglycans Facilitate the Cluster-of-Differentiation 14 (CD14)/Toll-like Receptor 4 (TLR4)-Dependent Inflammatory Response

LPS and IL-1 differentially activate mouse and human astrocytes: Role of CD14

(2014) Leonid Tarassishin et al.   GLIA

Soluble Heparan Sulfate Fragments Generated by Heparanase Trigger the Release of Pro-Inflammatory Cytokines through TLR-4

(2014) Katharine J. Goodall et al.   PLoS One

Induction of heparanase by HPV E6 oncogene in head and neck squamous cell carcinoma

(2013) Nir Hirshoren et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Heparan Sulfate: A Ubiquitous Glycosaminoglycan with Multiple Roles in Immunity

(2013) David Anak Simon Davis et al.   Frontiers in Immunology

Role of TGF-β in Survival of Phagocytizing Microglia: Autocrine Suppression of TNF-α Production and Oxidative Stress

(2013) Keun-Young Ryu et al.   Experimental Neurobiology

Heparanase overexpression impairs inflammatory response and macrophage-mediated clearance of amyloid-β in murine brain

(2012) Xiao Zhang et al.   ACTA NEUROPATHOLOGICA

Macrophage Activation by Heparanase Is Mediated by TLR-2 and TLR-4 and Associates With Plaque Progression

(2012) Miry Blich et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Heparan sulfate, an endogenous TLR4 agonist, promotes acute GVHD after allogeneic stem cell transplantation

(2012) T. V. Brennan et al.   BLOOD

Regulation of inflammasome signaling

(2012) Vijay A K Rathinam et al.   NATURE IMMUNOLOGY

Heparanase powers a chronic inflammatory circuit that promotes colitis-associated tumorigenesis in mice

(2011) Immanuel Lerner et al.   JOURNAL OF CLINICAL INVESTIGATION

A chemotactic gradient sequestered on endothelial heparan sulfate induces directional intraluminal crawling of neutrophils

(2010) S. Massena et al.   BLOOD

Astrogliosis in CNS Pathologies: Is There A Role for Microglia?

(2010) Dan Zhang et al.   MOLECULAR NEUROBIOLOGY

Neurodegeneration and the neuroimmune system

(2010) Joseph El Khoury   NATURE MEDICINE

Microglial activation and chronic neurodegeneration

(2010) Melinda E. Lull et al.   Neurotherapeutics

Syndecan-1 shedding facilitates the resolution of neutrophilic inflammation by removing sequestered CXC chemokines

(2009) K. Hayashida et al.   BLOOD

Neuroglia in neurodegeneration

(2009) Michael T. Heneka et al.   BRAIN RESEARCH REVIEWS

Pro-interleukin (IL)-1β Shares a Core Region of Stability as Compared with Mature IL-1β While Maintaining a Distinctly Different Configurational Landscape

(2009) Kendra L. Hailey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The NF- B Family of Transcription Factors and Its Regulation

(2009) A. Oeckinghaus et al.   Cold Spring Harbor Perspectives in Biology

Binding and uptake of Aβ1-42 by primary human astrocytesin vitro

(2008) Henrietta M. Nielsen et al.   GLIA

Cathepsin L Is Responsible for Processing and Activation of Proheparanase through Multiple Cleavages of a Linker Segment

(2008) Ghada Abboud-Jarrous et al.   JOURNAL OF BIOLOGICAL CHEMISTRY