Carrageenan Inhibits Insulin Signaling through GRB10-mediated Decrease in Tyr(P)-IRS1 and through Inflammation-induced Increase in Ser(P)307-IRS1

Insulin and Metabolic Stress Stimulate Multisite Serine/Threonine Phosphorylation of Insulin Receptor Substrate 1 and Inhibit Tyrosine Phosphorylation

(2014) Nancy J. Hançer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Central Role for GRB10 in Regulation of Islet Function in Man

(2014) Inga Prokopenko et al.   PLoS Genetics

Arylsulfatase B regulates versican expression by galectin-3 and AP-1 mediated transcriptional effects

(2013) S Bhattacharyya et al.   ONCOGENE

Mechanisms for Insulin Resistance: Common Threads and Missing Links

(2012) Varman T. Samuel et al.   CELL

Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2

(2012) K. D. Copps et al.   DIABETOLOGIA

Atlas of Genetics and Cytogenetics in Oncology and Haematology in 2013

(2012) Jean-Loup Huret et al.   NUCLEIC ACIDS RESEARCH

Exposure to the common food additive carrageenan leads to glucose intolerance, insulin resistance and inhibition of insulin signalling in HepG2 cells and C57BL/6J mice

(2011) S. Bhattacharyya et al.   DIABETOLOGIA

Distinct physiological and behavioural functions for parental alleles of imprinted Grb10

(2011) Alastair S. Garfield et al.   NATURE

Reciprocal imprinting of human GRB10 in placental trophoblast and brain: evolutionary conservation of reversed allelic expression

(2009) David Monk et al.   HUMAN MOLECULAR GENETICS

B-cell CLL/Lymphoma 10 (BCL10) Is Required for NF-κB Production by Both Canonical and Noncanonical Pathways and for NF-κB-inducing Kinase (NIK) Phosphorylation

(2009) Sumit Bhattacharyya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GRB10 gene and type 2 diabetes in Whites

(2009) R. Di Paola et al.   JOURNAL OF INTERNAL MEDICINE

Carrageenan-induced innate immune response is modified by enzymes that hydrolyze distinct galactosidic bonds

(2009) Sumit Bhattacharyya et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Structural and functional studies of the Ras-associating and pleckstrin-homology domains of Grb10 and Grb14

(2009) Rafael S Depetris et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Phosphorylation of IRS proteins, insulin action, and insulin resistance

(2008) Sigalit Boura-Halfon et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Carrageenan-induced NFκB activation depends on distinct pathways mediated by reactive oxygen species and Hsp27 or by Bcl10

(2008) S BHATTACHARYYA et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Type 2 Diabetes Mellitus in a Non-Obese Mouse Model Induced by Meg1/Grb10 Overexpression

(2008) Yoshie YAMAMOTO et al.   EXPERIMENTAL ANIMALS

Toll-like Receptor 4 Mediates Induction of the Bcl10-NFκB-Interleukin-8 Inflammatory Pathway by Carrageenan in Human Intestinal Epithelial Cells

(2008) Sumit Bhattacharyya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Galα1,3Galβ1,4GlcNAc-R (α-Gal) epitope: A carbohydrate of unique evolution and clinical relevance

(2007) Bruce A. Macher et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS