Processing by Convertases Is Required for Glypican-3-induced Inhibition of Hedgehog Signaling

Demystifying Heparan Sulfate–Protein Interactions

(2014) Ding Xu et al.   Annual Review of Biochemistry

Inactivation of Wnt signaling by a human antibody that recognizes the heparan sulfate chains of glypican-3 for liver cancer therapy

(2014) Wei Gao et al.   HEPATOLOGY

Glypican-3 binds to Frizzled and plays a direct role in the stimulation of canonical Wnt signaling

(2014) M. Capurro et al.   JOURNAL OF CELL SCIENCE

The role of glypicans in Hedgehog signaling

(2014) Jorge Filmus et al.   MATRIX BIOLOGY

LRP1 mediates Hedgehog-induced endocytosis of the GPC3-Hedgehog complex

(2012) M. I. Capurro et al.   JOURNAL OF CELL SCIENCE

Heparan Sulfate Biosynthesis

(2012) Johan Kreuger et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Novel Contact-dependent Bone Morphogenetic Protein (BMP) Signaling Mediated by Heparan Sulfate Proteoglycans

(2011) Katsufumi Dejima et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glypican-5 stimulates rhabdomyosarcoma cell proliferation by activating Hedgehog signaling

(2011) Fuchuan Li et al.   JOURNAL OF CELL BIOLOGY

The cell-surface proteins Dally-like and Ihog differentially regulate Hedgehog signaling strength and range during development

(2010) D. Yan et al.   DEVELOPMENT

A Novel Mechanism of Sequestering Fibroblast Growth Factor 2 by Glypican in Lipid Rafts, Allowing Skeletal Muscle Differentiation

(2010) J. Gutierrez et al.   MOLECULAR AND CELLULAR BIOLOGY

Dally-like core protein and its mammalian homologues mediate stimulatory and inhibitory effects on Hedgehog signal response

(2010) E. H. Williams et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Core Protein of Glypican Dally-Like Determines Its Biphasic Activity in Wingless Morphogen Signaling

(2009) Dong Yan et al.   DEVELOPMENTAL CELL

Overgrowth of a mouse model of Simpson– Golabi–Behmel syndrome is partly mediated by Indian Hedgehog

(2009) Mariana I Capurro et al.   EMBO REPORTS

Investigating the Elusive Mechanism of Glycosaminoglycan Biosynthesis

(2009) Xylophone V. Victor et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glypican-3 Inhibits Hedgehog Signaling during Development by Competing with Patched for Hedgehog Binding

(2008) Mariana I. Capurro et al.   DEVELOPMENTAL CELL

Glypicans

(2008) Jorge Filmus et al.   GENOME BIOLOGY

Dally regulates Dpp morphogen gradient formation by stabilizing Dpp on the cell surface

(2007) Takuya Akiyama et al.   DEVELOPMENTAL BIOLOGY