Global Kinetic Analysis of Mammalian E3 Reveals pH-dependent NAD+/NADH Regulation, Physiological Kinetic Reversibility, and Catalytic Optimum

The role of Pyruvate Dehydrogenase Complex in cardiovascular diseases

(2015) Wanqing Sun et al.   LIFE SCIENCES

A pH-Dependent Kinetic Model of Dihydrolipoamide Dehydrogenase from Multiple Organisms

(2014) Michael A. Moxley et al.   BIOPHYSICAL JOURNAL

The Pyruvate Dehydrogenase Complexes: Structure-based Function and Regulation

(2014) Mulchand S. Patel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic activation of pyruvate dehydrogenase alters oxidative substrate selection to induce skeletal muscle insulin resistance

(2014) Yasmeen Rahimi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipoamide Channel-Binding Sulfonamides Selectively Inhibit Mycobacterial Lipoamide Dehydrogenase

(2013) Ruslana Bryk et al.   BIOCHEMISTRY

Analysis of the Kinetics and Bistability of Ubiquinol:Cytochrome c Oxidoreductase

(2013) Jason N. Bazil et al.   BIOPHYSICAL JOURNAL

A century of enzyme kinetic analysis, 1913 to 2013

(2013) Kenneth A. Johnson   FEBS LETTERS

Uncovering the beginning of diabetes: the cellular redox status and oxidative stress as starting players in hyperglycemic damage

(2013) João Soeiro Teodoro et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Regulation of Muscle Pyruvate Dehydrogenase Complex in Insulin Resistance: Effects of Exercise and Dichloroacetate

(2013) Dumitru Constantin-Teodosiu   Diabetes & Metabolism Journal

Targeting mitochondrial oxidative metabolism as an approach to treat heart failure

(2012) Natasha Fillmore et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Pyridine Nucleotide Regulation of Cardiac Intermediary Metabolism

(2012) John R. Ussher et al.   CIRCULATION RESEARCH

The dynamic regulation of NAD metabolism in mitochondria

(2012) Liana Roberts Stein et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Flicking the Warburg Switch—Tyrosine Phosphorylation of Pyruvate Dehydrogenase Kinase Regulates Mitochondrial Activity in Cancer Cells

(2011) Almut Schulze et al.   MOLECULAR CELL

Myocardial Fatty Acid Metabolism in Health and Disease

(2010) Gary D. Lopaschuk et al.   PHYSIOLOGICAL REVIEWS

Pyruvate into lactate and back: From the Warburg effect to symbiotic energy fuel exchange in cancer cells

(2009) Olivier Feron   RADIOTHERAPY AND ONCOLOGY

Tissue-specific pyruvate dehydrogenase complex deficiency causes cardiac hypertrophy and sudden death of weaned male mice

(2008) Sukhdeep Sidhu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Structural and Functional Insights into the Molecular Mechanisms Responsible for the Regulation of Pyruvate Dehydrogenase Kinase 2

(2008) Todd Green et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pyruvate Dehydrogenase Complex Activity Controls Metabolic and Malignant Phenotype in Cancer Cells

(2008) Thomas McFate et al.   JOURNAL OF BIOLOGICAL CHEMISTRY