The Transcription Factor Bach2 Is Phosphorylated at Multiple Sites in Murine B Cells but a Single Site Prevents Its Nuclear Localization

Heme binds to an intrinsically disordered region of Bach2 and alters its conformation

(2015) Miki Watanabe-Matsui et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Crosstalk between Signaling Pathways Provided by Single and Multiple Protein Phosphorylation Sites

(2015) Hafumi Nishi et al.   JOURNAL OF MOLECULAR BIOLOGY

Super-enhancers delineate disease-associated regulatory nodes in T cells

(2015) Golnaz Vahedi et al.   NATURE

Innate immune regulation by STAT-mediated transcriptional mechanisms

(2014) Haiyan S. Li et al.   IMMUNOLOGICAL REVIEWS

Orchestration of plasma cell differentiation by Bach2 and its gene regulatory network

(2014) Kazuhiko Igarashi et al.   IMMUNOLOGICAL REVIEWS

The transcription repressors Bach2 and Bach1 promote B cell development by repressing the myeloid program

(2014) Ari Itoh-Nakadai et al.   NATURE IMMUNOLOGY

The structural basis for mTOR function

(2014) Domagoj Baretić et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The Menin–Bach2 axis is critical for regulating CD4 T-cell senescence and cytokine homeostasis

(2014) Makoto Kuwahara et al.   Nature Communications

Identification of Novel Genetic Loci Associated with Thyroid Peroxidase Antibodies and Clinical Thyroid Disease

(2014) Marco Medici et al.   PLoS Genetics

Signaling by the Phosphoinositide 3-Kinase Family in Immune Cells

(2013) Klaus Okkenhaug   Annual Review of Immunology

Brief Report: Identification ofBACH2andRAD51Bas Rheumatoid Arthritis Susceptibility Loci in a Meta-Analysis of Genome-Wide Data

(2013) Kate McAllister et al.   ARTHRITIS AND RHEUMATISM

Repression of the Transcription Factor Bach2 Contributes to Predisposition of IgG1 Memory B Cells toward Plasma Cell Differentiation

(2013) Kohei Kometani et al.   IMMUNITY

Transcription repressor Bach2 is required for pulmonary surfactant homeostasis and alveolar macrophage function

(2013) Atsushi Nakamura et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Bach2 Regulates Homeostasis of Foxp3+ Regulatory T Cells and Protects against Fatal Lung Disease in Mice

(2013) E. H. Kim et al.   JOURNAL OF IMMUNOLOGY

BACH2 represses effector programs to stabilize Treg-mediated immune homeostasis

(2013) Rahul Roychoudhuri et al.   NATURE

BACH2 mediates negative selection and p53-dependent tumor suppression at the pre-B cell receptor checkpoint

(2013) Srividya Swaminathan et al.   NATURE MEDICINE

Bach2 maintains T cells in a naive state by suppressing effector memory-related genes

(2013) S.-i. Tsukumo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A genome-wide regulatory network identifies key transcription factors for memory CD8+ T-cell development

(2013) Guangan Hu et al.   Nature Communications

Systematic Functional Prioritization of Protein Posttranslational Modifications

(2012) Pedro Beltrao et al.   CELL

NF- B, the first quarter-century: remarkable progress and outstanding questions

(2012) M. S. Hayden et al.   GENES & DEVELOPMENT

Genome-wide association analyses identify 13 new susceptibility loci for generalized vitiligo

(2012) Ying Jin et al.   NATURE GENETICS

A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation

(2012) Kyoko Ochiai et al.   NATURE IMMUNOLOGY

Heme regulates B-cell differentiation, antibody class switch, and heme oxygenase-1 expression in B cells as a ligand of Bach2

(2011) M. Watanabe-Matsui et al.   BLOOD

Identification of IL6R and chromosome 11q13.5 as risk loci for asthma

(2011) Manuel AR Ferreira et al.   LANCET

The mTOR-Regulated Phosphoproteome Reveals a Mechanism of mTORC1-Mediated Inhibition of Growth Factor Signaling

(2011) P. P. Hsu et al.   SCIENCE

Genome-Wide Association Analysis of Autoantibody Positivity in Type 1 Diabetes Cases

(2011) Vincent Plagnol et al.   PLoS Genetics

Regulation of immunity and oncogenesis by the IRF transcription factor family

(2010) David Savitsky et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Bach2 represses plasma cell gene regulatory network in B cells to promote antibody class switch

(2010) Akihiko Muto et al.   EMBO JOURNAL

Multiple common variants for celiac disease influencing immune gene expression

(2010) Patrick C A Dubois et al.   NATURE GENETICS

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate

(2010) Yin C Lin et al.   NATURE IMMUNOLOGY

Phosphoproteomic Analysis Reveals Interconnected System-Wide Responses to Perturbations of Kinases and Phosphatases in Yeast

(2010) B. Bodenmiller et al.   Science Signaling

An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1

(2009) Carson C. Thoreen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of the plasma cell transcription factor Blimp-1 gene by Bach2 and Bcl6

(2008) K. Ochiai et al.   INTERNATIONAL IMMUNOLOGY

Isolation of Hyperactive Mutants of Mammalian Target of Rapamycin

(2008) Yoichiro Ohne et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci

(2008) Jason D Cooper et al.   NATURE GENETICS