Enhancing Autophagy with Drugs or Lung-directed Gene Therapy Reverses the Pathological Effects of Respiratory Epithelial Cell Proteinopathy
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Enhancing Autophagy with Drugs or Lung-directed Gene Therapy Reverses the Pathological Effects of Respiratory Epithelial Cell Proteinopathy
Authors
Keywords
-
Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 290, Issue 50, Pages 29742-29757
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2015-10-23
DOI
10.1074/jbc.m115.691253
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Induced pluripotent stem cells model personalized variations in liver disease resulting from α1-antitrypsin deficiency
- (2015) Edgar N. Tafaleng et al. HEPATOLOGY
- Fibrosis — A Common Pathway to Organ Injury and Failure
- (2015) Don C. Rockey et al. NEW ENGLAND JOURNAL OF MEDICINE
- A C. elegans model of human α1-antitrypsin deficiency links components of the RNAi pathway to misfolded protein turnover
- (2014) Olivia S. Long et al. HUMAN MOLECULAR GENETICS
- Fluphenazine Reduces Proteotoxicity in C. elegans and Mammalian Models of Alpha-1-Antitrypsin Deficiency
- (2014) Jie Li et al. PLoS One
- FAK-Related Nonkinase Is a Multifunctional Negative Regulator of Pulmonary Fibrosis
- (2013) Qiang Ding et al. AMERICAN JOURNAL OF PATHOLOGY
- IL-22 Is Essential for Lung Epithelial Repair following Influenza Infection
- (2013) Derek A. Pociask et al. AMERICAN JOURNAL OF PATHOLOGY
- Future Directions in Idiopathic Pulmonary Fibrosis Research. An NHLBI Workshop Report
- (2013) Timothy S. Blackwell et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Gene transfer of master autophagy regulator TFEB results in clearance of toxic protein and correction of hepatic disease in alpha-1-anti-trypsin deficiency
- (2013) Nunzia Pastore et al. EMBO Molecular Medicine
- Enhanced autophagy ameliorates cardiac proteinopathy
- (2013) Md. Shenuarin Bhuiyan et al. JOURNAL OF CLINICAL INVESTIGATION
- Autophagy-enhancing drug carbamazepine diminishes hepatocellular death in fibrinogen storage disease
- (2013) Florian Puls et al. JOURNAL OF HEPATOLOGY
- Outcomes for recipients of liver transplantation for alpha-1-antitrypsin deficiency-related cirrhosis
- (2013) Elizabeth J. Carey et al. LIVER TRANSPLANTATION
- The Alveolar Epithelium Determines Susceptibility to Lung Fibrosis in Hermansky-Pudlak Syndrome
- (2012) Lisa R. Young et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Efficient and rapid isolation and purification of mouse alveolar type II epithelial cells
- (2012) Elise M. Messier et al. EXPERIMENTAL LUNG RESEARCH
- The Registry of the International Society for Heart and Lung Transplantation: 29th Adult Lung and Heart-Lung Transplant Report—2012
- (2012) Jason D. Christie et al. JOURNAL OF HEART AND LUNG TRANSPLANTATION
- Prostaglandin E2 protects murine lungs from bleomycin-induced pulmonary fibrosis and lung dysfunction
- (2011) Ryan T. Dackor et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Alveolar Epithelial Cells Undergo Epithelial-to-Mesenchymal Transition in Response to Endoplasmic Reticulum Stress
- (2011) Harikrishna Tanjore et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Survival benefit of lung transplantation in individuals with severe α1-anti-trypsin deficiency (PiZZ) and emphysema
- (2011) Hanan A. Tanash et al. JOURNAL OF HEART AND LUNG TRANSPLANTATION
- Ligand-independent transforming growth factor-β type I receptor signalling mediates type I collagen-induced epithelial-mesenchymal transition
- (2011) Lucas DeMaio et al. JOURNAL OF PATHOLOGY
- Lung Volumes and Emphysema in Smokers with Interstitial Lung Abnormalities
- (2011) George R. Washko et al. NEW ENGLAND JOURNAL OF MEDICINE
- Smoking and Subclinical Interstitial Lung Disease
- (2011) Talmadge E. King NEW ENGLAND JOURNAL OF MEDICINE
- Endoplasmic reticulum stress enhances fibrotic remodeling in the lungs
- (2011) W. E. Lawson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TFEB Links Autophagy to Lysosomal Biogenesis
- (2011) C. Settembre et al. SCIENCE
- Impaired Autophagy in Sporadic Inclusion-Body Myositis and in Endoplasmic Reticulum Stress-Provoked Cultured Human Muscle Fibers
- (2010) Anna Nogalska et al. AMERICAN JOURNAL OF PATHOLOGY
- Role of Endoplasmic Reticulum Stress in Epithelial–Mesenchymal Transition of Alveolar Epithelial Cells
- (2010) Qian Zhong et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Alpha-1-Antitrypsin Deficiency: Importance of Proteasomal and Autophagic Degradative Pathways in Disposal of Liver Disease–Associated Protein Aggregates
- (2010) David H. Perlmutter Annual Review of Medicine
- An Autophagy-Enhancing Drug Promotes Degradation of Mutant 1-Antitrypsin Z and Reduces Hepatic Fibrosis
- (2010) T. Hidvegi et al. SCIENCE
- Exploring the role of CT densitometry: a randomised study of augmentation therapy in 1-antitrypsin deficiency
- (2009) A. Dirksen et al. EUROPEAN RESPIRATORY JOURNAL
- Large-Scale Production of High-Quality Helper-Dependent Adenoviral Vectors Using Adherent Cells in Cell Factories
- (2009) Masataka Suzuki et al. HUMAN GENE THERAPY
- Basement membrane remodelling and segmental fibrosis in sporadic inclusion body myositis
- (2009) K. Doppler et al. NEUROMUSCULAR DISORDERS
- Alpha1-Antitrypsin Deficiency
- (2009) Edwin K. Silverman et al. NEW ENGLAND JOURNAL OF MEDICINE
- Genetic Defects in Surfactant Protein A2 Are Associated with Pulmonary Fibrosis and Lung Cancer
- (2008) Yongyu Wang et al. AMERICAN JOURNAL OF HUMAN GENETICS
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now