The Natural ProductN-Palmitoyl-l-leucine Selectively Inhibits Late Assembly of Human Spliceosomes

Identification of Small Molecule Inhibitors of Pre-mRNA Splicing

(2014) Andrea Pawellek et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

“Function-First” Lead Discovery: Mode of Action Profiling of Natural Product Libraries Using Image-Based Screening

(2013) Christopher J. Schulze et al.   CHEMISTRY & BIOLOGY

Coherence between Cellular Responses andin VitroSplicing Inhibition for the Anti-tumor Drug Pladienolide B and Its Analogs

(2013) Kerstin A. Effenberger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Large-scale cytological profiling for functional analysis of bioactive compounds

(2013) Marcos H. Woehrmann et al.   Molecular BioSystems

Psoromic Acid Derivatives: A New Family of Small-Molecule Pre-mRNA Splicing Inhibitors Discovered by a Stage-Specific High-Throughput in Vitro Splicing Assay

(2012) Timur R. Samatov et al.   CHEMBIOCHEM

A Quantitative High-Throughput In Vitro Splicing Assay Identifies Inhibitors of Spliceosome Catalysis

(2012) M. G. Berg et al.   MOLECULAR AND CELLULAR BIOLOGY

Reduced fidelity of branch point recognition and alternative splicing induced by the anti-tumor drug spliceostatin A

(2011) A. Corrionero et al.   GENES & DEVELOPMENT

The anti-tumor drug E7107 reveals an essential role for SF3b in remodeling U2 snRNP to expose the branch point-binding region

(2011) E. G. Folco et al.   GENES & DEVELOPMENT

Spliceostatin A inhibits spliceosome assembly subsequent to prespliceosome formation

(2010) Gabriel A. Roybal et al.   NUCLEIC ACIDS RESEARCH

The A–Z of bacterial translation inhibitors

(2009) Daniel N. Wilson   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Identification of endogenous acyl amino acids based on a targeted lipidomics approach

(2009) Bo Tan et al.   JOURNAL OF LIPID RESEARCH

The Biflavonoid Isoginkgetin Is a General Inhibitor of Pre-mRNA Splicing

(2008) Kristine O'Brien et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Searching for a wrench to throw into the splicing machine

(2007) Melissa S Jurica   Nature Chemical Biology