The Transitional Endoplasmic Reticulum ATPase p97 Regulates the Alternative Nuclear Factor NF-κB Signaling via Partial Degradation of the NF-κB Subunit p100

The kinase MST4 limits inflammatory responses through direct phosphorylation of the adaptor TRAF6

(2015) Shi Jiao et al.   NATURE IMMUNOLOGY

Enhanced Protein Degradation by Branched Ubiquitin Chains

(2014) Hermann-Josef Meyer et al.   CELL

Striatins Contain a Noncanonical Coiled Coil That Binds Protein Phosphatase 2A A Subunit to Form a 2:2 Heterotetrameric Core of Striatin-interacting Phosphatase and Kinase (STRIPAK) Complex

(2014) Cuicui Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quantitative Dissection and Modeling of the NF-κB p100-p105 Module Reveals Interdependent Precursor Proteolysis

(2014) Zekiye Buket Yılmaz et al.   Cell Reports

Ter94 ATPase Complex Targets K11-Linked Ubiquitinated Ci to Proteasomes for Partial Degradation

(2013) Zhao Zhang et al.   DEVELOPMENTAL CELL

A unique IBMPFD-related P97/VCP mutation with differential binding pattern and subcellular localization

(2013) Yalcin Erzurumlu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Altered Intersubunit Communication Is the Molecular Basis for Functional Defects of Pathogenic p97 Mutants

(2013) Wai Kwan Tang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The p97-UFD1L-NPL4 Protein Complex Mediates Cytokine-Induced I B  Proteolysis

(2013) J.-M. Li et al.   MOLECULAR AND CELLULAR BIOLOGY

p97 complexes as signal integration hubs

(2012) Hemmo Meyer   BMC BIOLOGY

Balance between NF- B p100 and p52 Regulates T Cell Costimulation Dependence

(2012) M. L. Giardino Torchia et al.   JOURNAL OF IMMUNOLOGY

SCFFbw7 Modulates the NFκB Signaling Pathway by Targeting NFκB2 for Ubiquitination and Destruction

(2012) Hidefumi Fukushima et al.   Cell Reports

Cdc48/p97 Mediates UV-Dependent Turnover of RNA Pol II

(2011) Rati Verma et al.   MOLECULAR CELL

CDC-48/p97 Coordinates CDT-1 Degradation with GINS Chromatin Dissociation to Ensure Faithful DNA Replication

(2011) André Franz et al.   MOLECULAR CELL

The AAA-ATPase VCP/p97 promotes 53BP1 recruitment by removing L3MBTL1 from DNA double-strand breaks

(2011) Klara Acs et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Inclusion body myopathy, Paget's disease of the bone and fronto-temporal dementia: a disorder of autophagy

(2010) J. S. Ju et al.   HUMAN MOLECULAR GENETICS

Two Australian families with inclusion-body myopathy, Paget’s disease of bone and frontotemporal dementia: Novel clinical and genetic findings

(2010) Kishore R. Kumar et al.   NEUROMUSCULAR DISORDERS

Multilayered Mechanism of CD4 Downregulation by HIV-1 Vpu Involving Distinct ER Retention and ERAD Targeting Steps

(2010) Javier G. Magadán et al.   PLoS Pathogens

Clinical outcome in 19 French and Spanish patients with valosin-containing protein myopathy associated with Paget’s disease of bone and frontotemporal dementia

(2009) Tanya Stojkovic et al.   NEUROMUSCULAR DISORDERS

UBXD7 Binds Multiple Ubiquitin Ligases and Implicates p97 in HIF1α Turnover

(2008) Gabriela Alexandru et al.   CELL