Dehydroepiandrosterone Activation of G-protein-coupled Estrogen Receptor Rapidly Stimulates MicroRNA-21 Transcription in Human Hepatocellular Carcinoma Cells

Decrease expression of microRNA-744 promotes cell proliferation by targeting c-Myc in human hepatocellular carcinoma

(2014) Feng Lin et al.   Cancer Cell International

Regulation of the Extrinsic Apoptotic Pathway by MicroRNA-21 in Alcoholic Liver Injury

(2014) Heather Francis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNAs and SerpinB3 in hepatocellular carcinoma

(2014) Cristian Turato et al.   LIFE SCIENCES

Dehydroepiandrosterone-induces miR-21 transcription in HepG2 cells through estrogen receptor β and androgen receptor

(2014) Yun Teng et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Estrogen biology: New insights into GPER function and clinical opportunities

(2014) Eric R. Prossnitz et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

ER-α36-Mediated Rapid Estrogen Signaling Positively Regulates ER-Positive Breast Cancer Stem/Progenitor Cells

(2014) Hao Deng et al.   PLoS One

Thyroid Hormone Regulation of miR-21 Enhances Migration and Invasion of Hepatoma

(2013) Y.-H. Huang et al.   CANCER RESEARCH

Differential Effects of Dehydroepiandrosterone and Testosterone in Prostate and Colon Cancer Cell Apoptosis: The Role of Nerve Growth Factor (NGF) Receptors

(2013) Vasileia Anagnostopoulou et al.   ENDOCRINOLOGY

Loss of 5α-Reductase Type 1 Accelerates the Development of Hepatic Steatosis but Protects Against Hepatocellular Carcinoma in Male Mice

(2013) Joanna K. Dowman et al.   ENDOCRINOLOGY

Liquid Chromatography–Tandem Mass Spectrometry Analysis of Human Adrenal Vein 19-Carbon Steroids Before and After ACTH Stimulation

(2013) Juilee Rege et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Insight into the mechanisms of action of estrogen receptor β in the breast, prostate, colon, and CNS

(2013) Prasenjit Dey et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Acetylcholine Acts on Androgen Receptor to Promote the Migration and Invasion but Inhibit the Apoptosis of Human Hepatocarcinoma

(2013) Huizhen Nie et al.   PLoS One

Stimulation of the Sigma-1 Receptor by DHEA Enhances Synaptic Efficacy and Neurogenesis in the Hippocampal Dentate Gyrus of Olfactory Bulbectomized Mice

(2013) Shigeki Moriguchi et al.   PLoS One

A Review of Age-Related Dehydroepiandrosterone Decline and Its Association with Well-Known Geriatric Syndromes: Is Treatment Beneficial?

(2013) Nikolaos Samaras et al.   REJUVENATION RESEARCH

Inactivation of GPR30 reduces growth of triple-negative breast cancer cells: possible application in targeted therapy

(2012) Rainer Girgert et al.   BREAST CANCER RESEARCH AND TREATMENT

Foxa1 and Foxa2 Are Essential for Sexual Dimorphism in Liver Cancer

(2012) Zhaoyu Li et al.   CELL

Minireview: G Protein-Coupled Estrogen Receptor-1, GPER-1: Its Mechanism of Action and Role in Female Reproductive Cancer, Renal and Vascular Physiology

(2012) Edward J. Filardo et al.   ENDOCRINOLOGY

Membrane Estrogen Signaling Enhances Tumorigenesis and Metastatic Potential of Breast Cancer Cells via Estrogen Receptor-α36 (ERα36)

(2012) Reyhaan A. Chaudhri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Estrogen Represses Hepatocellular Carcinoma (HCC) Growth via Inhibiting Alternative Activation of Tumor-associated Macrophages (TAMs)

(2012) Weiwei Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

G Protein-coupled Estrogen Receptor Mediates the Up-regulation of Fatty Acid Synthase Induced by 17β-Estradiol in Cancer Cells and Cancer-associated Fibroblasts

(2012) Maria Francesca Santolla et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Diagnostic and therapeutic potential of miRNA signatures in patients with hepatocellular carcinoma

(2012) Florie Borel et al.   JOURNAL OF HEPATOLOGY

Estrogen Regulates Hepcidin Expression via GPR30-BMP6-Dependent Signaling in Hepatocytes

(2012) Yasumasa Ikeda et al.   PLoS One

Disease-linked microRNA-21 exhibits drastically reduced mRNA binding and silencing activity in healthy mouse liver

(2012) J. R. Androsavich et al.   RNA

The DHEA metabolite 7β-hydroxy-epiandrosterone exerts anti-estrogenic effects on breast cancer cell lines

(2012) Sandra Niro et al.   STEROIDS

Gender Differences in Cancer Susceptibility: An Inadequately Addressed Issue

(2012) M. Tevfik Dorak et al.   Frontiers in Genetics

miR-22 Promotes HBV-Related Hepatocellular Carcinoma Development in Males

(2011) R. Jiang et al.   CLINICAL CANCER RESEARCH

Circulating MicroRNAs as Biomarkers for Hepatocellular Carcinoma

(2011) Kevin Z. Qu et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Dehydroepiandrosterone (DHEA)—A Precursor Steroid or an Active Hormone in Human Physiology (CME)

(2011) Abdulmaged M. Traish et al.   Journal of Sexual Medicine

Estrogens promote proliferation of the seminoma-like TCam-2 cell line through a GPER-dependent ERα36 induction

(2011) Angelina Wallacides et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The G-protein-coupled estrogen receptor GPER in health and disease

(2011) Eric R. Prossnitz et al.   Nature Reviews Endocrinology

Hepatocellular Carcinoma

(2011) Hashem B. El-Serag   NEW ENGLAND JOURNAL OF MEDICINE

Expression of Wild-Type and Variant Estrogen Receptor Alpha in Liver Carcinogenesis and Tumor Progression

(2011) Vitale Miceli et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Circulating MicroRNAs in Patients with Chronic Hepatitis C and Non-Alcoholic Fatty Liver Disease

(2011) Silvia Cermelli et al.   PLoS One

Interplay of estrogen receptors and GPR30 for the regulation of early membrane initiated transcriptional effects: A pharmacological approach

(2011) George Notas et al.   STEROIDS

FRET analysis of protein tyrosine kinase c-Src activation mediated via aryl hydrocarbon receptor

(2010) Bin Dong et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Curcumin regulates miR-21 expression and inhibits invasion and metastasis in colorectal cancer

(2010) Giridhar Mudduluru et al.   BIOSCIENCE REPORTS

Nuclear Alternate Estrogen Receptor GPR30 Mediates 17 -Estradiol-Induced Gene Expression and Migration in Breast Cancer-Associated Fibroblasts

(2010) A. Madeo et al.   CANCER RESEARCH

Activation of GPR30 inhibits the growth of prostate cancer cells through sustained activation of Erk1/2, c-jun/c-fos-dependent upregulation of p21 and induction of G2 cell-cycle arrest

(2010) Q K Y Chan et al.   CELL DEATH AND DIFFERENTIATION

Induction of miR-21 by Retinoic Acid in Estrogen Receptor-positive Breast Carcinoma Cells

(2010) Mineko Terao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Estrogen Receptor β Binds to and Regulates Three Distinct Classes of Target Genes

(2010) Omar I. Vivar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Involvement of Estrogen Receptor Variant ER-α36, Not GPR30, in Nongenomic Estrogen Signaling

(2010) Lianguo Kang et al.   MOLECULAR ENDOCRINOLOGY

Androgen Receptor Promotes Hepatitis B Virus-Induced Hepatocarcinogenesis Through Modulation of Hepatitis B Virus RNA Transcription

(2010) M. H. Wu et al.   Science Translational Medicine

Gonadotropin-Releasing Hormone-Mediated Phosphorylation of Estrogen Receptor-α Contributes tofosBExpression in Mouse Gonadotrophs

(2009) Junling Chen et al.   ENDOCRINOLOGY

Estrogen receptor-alpha (ER-α) suppresses expression of its variant ER-α36

(2009) Yi Zou et al.   FEBS LETTERS

Mechanisms of estrogen signaling and gene expression via GPR30

(2009) Eric R. Prossnitz et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

In vivo effects of a GPR30 antagonist

(2009) Megan K Dennis et al.   Nature Chemical Biology

Methyl-β-cyclodextrin, a specific cholesterol-binding agent, inhibits melanogenesis in human melanocytes through activation of ERK

(2008) Sun Hee Jin et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

miR-21 Gene Expression Triggered by AP-1 Is Sustained through a Double-Negative Feedback Mechanism

(2008) Shuji Fujita et al.   JOURNAL OF MOLECULAR BIOLOGY

Signal Transducer and Activator of Transcription 5b, c-Src, and Epidermal Growth Factor Receptor Signaling Play Integral Roles in Estrogen-Stimulated Proliferation of Estrogen Receptor-Positive Breast Cancer Cells

(2008) Emily M. Fox et al.   MOLECULAR ENDOCRINOLOGY

MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene

(2008) Z Lu et al.   ONCOGENE

Estradiol Stimulates Transcription of Nuclear Respiratory Factor-1 and Increases Mitochondrial Biogenesis

(2007) Kathleen A. Mattingly et al.   MOLECULAR ENDOCRINOLOGY