Short Term Exposure of Beta Cells to Low Concentrations of Interleukin-1β Improves Insulin Secretion through Focal Adhesion and Actin Remodeling and Regulation of Gene Expression

Targeting inflammation in the treatment of type 2 diabetes: time to start

(2014) Marc Y. Donath   NATURE REVIEWS DRUG DISCOVERY

Non-muscle myosin IIA is involved in focal adhesion and actin remodelling controlling glucose-stimulated insulin secretion

(2013) C. Arous et al.   DIABETOLOGIA

Interleukin-1 antagonism in type 1 diabetes of recent onset: two multicentre, randomised, double-blind, placebo-controlled trials

(2013) Antoinette Moran et al.   LANCET

IL-1β enhances cell adhesion to degraded fibronectin

(2012) Dhaarmini Rajshankar et al.   FASEB JOURNAL

Differential analysis of gene regulation at transcript resolution with RNA-seq

(2012) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

The GEM mapper: fast, accurate and versatile alignment by filtration

(2012) Santiago Marco-Sola et al.   NATURE METHODS

Focal Adhesion Remodeling Is Crucial for Glucose-Stimulated Insulin Secretion and Involves Activation of Focal Adhesion Kinase and Paxillin

(2011) D. Rondas et al.   DIABETES

Focal adhesions and Ras are functionally and spatially integrated to mediate IL-1 activation of ERK

(2011) Qin Wang et al.   FASEB JOURNAL

High-Resolution Quantification of Focal Adhesion Spatiotemporal Dynamics in Living Cells

(2011) Mathew E. Berginski et al.   PLoS One

Actin Cytoskeleton Participation in the Onset of IL-1β Induction of an Invasive Mesenchymal-like Phenotype in Epithelial MCF-7 Cells

(2010) Janusz Franco-Barraza et al.   ARCHIVES OF MEDICAL RESEARCH

Crosstalk of reactive oxygen species and NF-κB signaling

(2010) Michael J Morgan et al.   CELL RESEARCH

STAT1 Is a Master Regulator of Pancreatic β-Cell Apoptosis and Islet Inflammation

(2010) Fabrice Moore et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Blockade of interleukin 1 in type 1 diabetes mellitus

(2010) Thomas Mandrup-Poulsen et al.   Nature Reviews Endocrinology

Interleukin-1 (IL-1) Pathway

(2010) A. Weber et al.   Science Signaling

Cytokine production by islets in health and diabetes: cellular origin, regulation and function

(2010) Marc Y. Donath et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Paxillin-Y118 phosphorylation contributes to the control of Src-induced anchorage-independent growth by FAK and adhesion

(2009) Sanjay Sachdev et al.   BMC CANCER

Sustained Effects of Interleukin-1 Receptor Antagonist Treatment in Type 2 Diabetes

(2009) C. M. Larsen et al.   DIABETES CARE

The NF- B Family of Transcription Factors and Its Regulation

(2009) A. Oeckinghaus et al.   Cold Spring Harbor Perspectives in Biology

JNK regulates cell migration through promotion of tyrosine phosphorylation of paxillin

(2008) Zhi Huang et al.   CELLULAR SIGNALLING

Role of actin cytoskeleton in LPS-induced NF-κB activation and nitric oxide production in murine macrophages

(2008) Sandeepa M. Eswarappa et al.   Innate Immunity

Increased Interleukin (IL)-1β Messenger Ribonucleic Acid Expression in β-Cells of Individuals with Type 2 Diabetes and Regulation of IL-1β in Human Islets by Glucose and Autostimulation

(2008) Marianne Böni-Schnetzler et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Disruption of c-Jun Reduces Cellular Migration and Invasion through Inhibition of c-Src and Hyperactivation of ROCK II Kinase

(2008) Xuanmao Jiao et al.   MOLECULAR BIOLOGY OF THE CELL