Integrins Influence the Size and Dynamics of Signaling Microclusters in a Pyk2-dependent Manner

Integrin receptors on tumor cells facilitate NK cell-mediated antibody-dependent cytotoxicity

(2014) Nadia Anikeeva et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Protein Kinase C  Regulates Stability of the Peripheral Adhesion Ring Junction and Contributes to the Sensitivity of Target Cell Lysis by CTL

(2014) A. M. Beal et al.   JOURNAL OF IMMUNOLOGY

A signaling network stimulated by  2 integrin promotes the polarization of lytic granules in cytotoxic cells

(2014) M. Zhang et al.   Science Signaling

Distinct structural and catalytic roles for Zap70 in formation of the immunological synapse in CTL

(2014) Misty R Jenkins et al.   eLife

Modulation of T cell signaling by the actin cytoskeleton

(2013) Y. Yu et al.   JOURNAL OF CELL SCIENCE

Integrin inside-out signaling and the immunological synapse

(2011) Timothy A Springer et al.   CURRENT OPINION IN CELL BIOLOGY

Mechanisms controlling granule-mediated cytolytic activity of cytotoxic T lymphocytes

(2011) Nadia Anikeeva et al.   IMMUNOLOGIC RESEARCH

 2 Integrin Induces TCR -Syk-Phospholipase C-  Phosphorylation and Paxillin-Dependent Granule Polarization in Human NK Cells

(2011) M. E. March et al.   JOURNAL OF IMMUNOLOGY

Natural Killer Cell Lytic Granule Secretion Occurs through a Pervasive Actin Network at the Immune Synapse

(2011) Gregory D. Rak et al.   PLOS BIOLOGY

Integrin-linked kinase: a Scaffold protein unique among its ilk

(2011) Lina Dagnino   Journal of Cell Communication and Signaling

Cytotoxic immunological synapses

(2010) Michael L. Dustin et al.   IMMUNOLOGICAL REVIEWS

Diversity in immunological synapse structure

(2010) Timothy J. Thauland et al.   IMMUNOLOGY

T Cell Receptor Signaling Kinetics Takes the Stage

(2010) Y. Sykulev   Science Signaling

Microsignalosomes: spatially resolved receptor signalling

(2009) Bebhinn Treanor et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Integrin-Dependent Organization and Bidirectional Vesicular Traffic at Cytotoxic Immune Synapses

(2009) Dongfang Liu et al.   IMMUNITY

Kinetics of Early T Cell Receptor Signaling Regulate the Pathway of Lytic Granule Delivery to the Secretory Domain

(2009) Allison M. Beal et al.   IMMUNITY

Structural Characterization of Proline-rich Tyrosine Kinase 2 (PYK2) Reveals a Unique (DFG-out) Conformation and Enables Inhibitor Design

(2009) Seungil Han et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Adapter Protein SLP-76 Mediates "Outside-In" Integrin Signaling and Function in T Cells

(2009) R. G. Baker et al.   MOLECULAR AND CELLULAR BIOLOGY

T Cell Costimulation via the Integrin VLA-4 Inhibits the Actin-Dependent Centralization of Signaling Microclusters Containing the Adaptor SLP-76

(2008) Ken Nguyen et al.   IMMUNITY

Signal initiation in T-cell receptor microclusters

(2008) Maria-Cristina Seminario et al.   IMMUNOLOGICAL REVIEWS

Increased Mobility of Major Histocompatibility Complex I-Peptide Complexes Decreases the Sensitivity of Antigen Recognition

(2008) Jean-Manuel Segura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY