The Fab1/PIKfyve Phosphoinositide Phosphate Kinase Is Not Necessary to Maintain the pH of Lysosomes and of the Yeast Vacuole

Approaches for detecting lysosomal alkalinization and impaired degradation in fresh and cultured RPE cells: Evidence for a role in retinal degenerations

(2014) Sonia Guha et al.   EXPERIMENTAL EYE RESEARCH

SLC17A9 Protein Functions as a Lysosomal ATP Transporter and Regulates Cell Viability

(2014) Qi Cao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PIKfyve, a Class III Lipid Kinase, Is Required for TLR-Induced Type I IFN Production via Modulation of ATF3

(2014) X. Cai et al.   JOURNAL OF IMMUNOLOGY

The signaling lipid PI(3,5)P2 stabilizes V1–Vo sector interactions and activates the V-ATPase

(2014) Sheena Claire Li et al.   MOLECULAR BIOLOGY OF THE CELL

PIKfyve Inhibition Interferes with Phagosome and Endosome Maturation in Macrophages

(2014) Grace H.E. Kim et al.   TRAFFIC

Phosphatidylinositol 3,5-bisphosphate: Low abundance, high significance

(2013) Amber J. McCartney et al.   BIOESSAYS

PIKfyve, a Class III PI Kinase, Is the Target of the Small Molecular IL-12/IL-23 Inhibitor Apilimod and a Player in Toll-like Receptor Signaling

(2013) Xinming Cai et al.   CHEMISTRY & BIOLOGY

The biophysical and molecular basis of intracellular pH sensing by Na+/H+ exchanger-3

(2013) Victor Babich et al.   FASEB JOURNAL

Vac14 Protein Multimerization Is a Prerequisite Step for Fab1 Protein Complex Assembly and Function

(2013) Tamadher A. Alghamdi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PIKfyve Regulates the Endosomal Localization of CpG Oligodeoxynucleotides to Elicit TLR9-Dependent Cellular Responses

(2013) Kaoru Hazeki et al.   PLoS One

Membrane Protein Rim21 Plays a Central Role in Sensing Ambient pH inSaccharomyces cerevisiae

(2012) Keisuke Obara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TRPML: Transporters of metals in lysosomes essential for cell survival?

(2011) Kirill Kiselyov et al.   CELL CALCIUM

Phosphatidylinositol-3,5-Bisphosphate: No Longer the Poor PIP2

(2011) Cheuk Y. Ho et al.   TRAFFIC

A cation counterflux supports lysosomal acidification

(2010) Benjamin E. Steinberg et al.   JOURNAL OF CELL BIOLOGY

Extensive proteomic screening identifies the obesity-related NYGGF4 protein as a novel LRP-interactor, showing reduced expression in early Alzheimer's disease

(2010) Yuji Kajiwara et al.   Molecular Neurodegeneration

Quantitative Analysis of Endocytosis with Cytoplasmic pHluorin Chimeras

(2010) Derek C. Prosser et al.   TRAFFIC

PI(3,5)P2 controls membrane trafficking by direct activation of mucolipin Ca2+ release channels in the endolysosome

(2010) Xian-ping Dong et al.   Nature Communications

Chloroquine and its analogs: A new promise of an old drug for effective and safe cancer therapies

(2009) V. Raja Solomon et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

PIKfyve Regulation of Endosome-Linked Pathways

(2009) Jane de Lartigue et al.   TRAFFIC

The yeast lysosome-like vacuole: Endpoint and crossroads

(2008) Sheena Claire Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Molecular and cellular basis of lysosomal transmembrane protein dysfunction

(2008) Raquel Ruivo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Autophagy: A lysosomal degradation pathway with a central role in health and disease

(2008) Eeva-Liisa Eskelinen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

A selective PIKfyve inhibitor blocks PtdIns(3,5)P2 production and disrupts endomembrane transport and retroviral budding

(2008) Harold B J Jefferies et al.   EMBO REPORTS

Assembly of a Fab1 Phosphoinositide Kinase Signaling Complex Requires the Fig4 Phosphoinositide Phosphatase

(2008) Roberto J. Botelho et al.   MOLECULAR BIOLOGY OF THE CELL