The Predominant Molecular State of Bound Enzyme Determines the Strength and Type of Product Inhibition in the Hydrolysis of Recalcitrant Polysaccharides by Processive Enzymes

Fungal Cellulases

(2015) Christina M. Payne et al.   CHEMICAL REVIEWS

Chitosan-sheath and chitin-core nanowhiskers

(2014) Antonio G.B. Pereira et al.   CARBOHYDRATE POLYMERS

Towards a molecular-level theory of carbohydrate processivity in glycoside hydrolases

(2014) Gregg T Beckham et al.   CURRENT OPINION IN BIOTECHNOLOGY

Enzyme processivity changes with the extent of recalcitrant polysaccharide degradation

(2014) Anne Grethe Hamre et al.   FEBS LETTERS

Single-molecule Imaging Analysis of Elementary Reaction Steps ofTrichoderma reeseiCellobiohydrolase I (Cel7A) Hydrolyzing Crystalline Cellulose Iαand IIII

(2014) Yusuke Shibafuji et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Kinetics of Cellobiohydrolase (Cel7A) Variants with Lowered Substrate Affinity

(2014) Jeppe Kari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Probing Substrate Interactions in the Active Tunnel of a Catalytically Deficient Cellobiohydrolase (Cel7)

(2014) Francieli Colussi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fully Deacetylated Chitooligosaccharides Act as Efficient Glycoside Hydrolase Family 18 Chitinase Inhibitors

(2014) Lei Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Carbohydrate–Protein Interactions That Drive Processive Polysaccharide Translocation in Enzymes Revealed from a Computational Study of Cellobiohydrolase Processivity

(2014) Brandon C. Knott et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Trade-off between Processivity and Hydrolytic Velocity of Cellobiohydrolases at the Surface of Crystalline Cellulose

(2014) Akihiko Nakamura et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Multi-Mode Binding of Cellobiohydrolase Cel7A from Trichoderma reesei to Cellulose

(2014) Jürgen Jalak et al.   PLoS One

Two-way traffic of glycoside hydrolase family 18 processive chitinases on crystalline chitin

(2014) Kiyohiko Igarashi et al.   Nature Communications

Kinetic Modeling at Single-Molecule Resolution Elucidates the Mechanisms of Cellulase Synergy

(2014) Barry Z. Shang et al.   ACS Catalysis

A graphene screen-printed carbon electrode for real-time measurements of unoccupied active sites in a cellulase

(2013) Nicolaj Cruys-Bagger et al.   ANALYTICAL BIOCHEMISTRY

Transient Kinetics and Rate-Limiting Steps for the Processive Cellobiohydrolase Cel7A: Effects of Substrate Structure and Carbohydrate Binding Domain

(2013) Nicolaj Cruys-Bagger et al.   BIOCHEMISTRY

Two-Parameter Kinetic Model Based on a Time-Dependent Activity Coefficient Accurately Describes Enzymatic Cellulose Digestion

(2013) Maxim Kostylev et al.   BIOCHEMISTRY

Product inhibition of cellulases studied with 14C-labeled cellulose substrates

(2013) Hele Teugjas et al.   Biotechnology for Biofuels

Strong cellulase inhibitors from the hydrothermal pretreatment of wheat straw

(2013) Riin Kont et al.   Biotechnology for Biofuels

Product inhibition of five Hypocrea jecorina cellulases

(2013) Leigh Murphy et al.   ENZYME AND MICROBIAL TECHNOLOGY

The chitinolytic machinery ofSerratia marcescens- a model system for enzymatic degradation of recalcitrant polysaccharides

(2013) Gustav Vaaje-Kolstad et al.   FEBS Journal

Systems-level Modeling with Molecular Resolution Elucidates the Rate-limiting Mechanisms of Cellulose Decomposition by Cellobiohydrolases

(2013) Barry Z. Shang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Binding and Movement of Individual Cel7A Cellobiohydrolases on Crystalline Cellulose Surfaces Revealed by Single-molecule Fluorescence Imaging

(2013) Jaemyeong Jung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Mechanism of Cellulose Hydrolysis by a Two-Step, Retaining Cellobiohydrolase Elucidated by Structural and Transition Path Sampling Studies

(2013) Brandon C. Knott et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Glycoside Hydrolase Processivity Is Directly Related to Oligosaccharide Binding Free Energy

(2013) Christina M. Payne et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Increased enzyme binding to substrate is not necessary for more efficient cellulose hydrolysis

(2013) D. Gao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Xylan oligosaccharides and cellobiohydrolase I (TrCel7A) interaction and effect on activity

(2012) Martin J Baumann et al.   Biotechnology for Biofuels

Product Binding Varies Dramatically between Processive and Nonprocessive Cellulase Enzymes

(2012) Lintao Bu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pre-steady-state Kinetics for Hydrolysis of Insoluble Cellulose by Cellobiohydrolase Cel7A

(2012) Nicolaj Cruys-Bagger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endo-exo Synergism in Cellulose Hydrolysis Revisited

(2012) Jürgen Jalak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cellulase Linkers Are Optimized Based on Domain Type and Function: Insights from Sequence Analysis, Biophysical Measurements, and Molecular Simulation

(2012) Deanne W. Sammond et al.   PLoS One

Analysis of Noncovalent Chitinase-Chito-Oligosaccharide Complexes by Infrared-Matrix Assisted Laser Desorption Ionization and Nanoelectrospray Ionization Mass Spectrometry

(2011) Anette I. Dybvik et al.   ANALYTICAL CHEMISTRY

Initial- and Processive-Cut Products Reveal Cellobiohydrolase Rate Limitations and the Role of Companion Enzymes

(2011) Jerome M. Fox et al.   BIOCHEMISTRY

Determination of the molecular states of the processive endocellulase Thermobifida fusca Cel9A during crystalline cellulose depolymerization

(2011) Maxim Kostylev et al.   BIOTECHNOLOGY AND BIOENGINEERING

A kinetic model for the burst phase of processive cellulases

(2011) Eigil Praestgaard et al.   FEBS Journal

Substrate positioning in chitinase A, a processive chito-biohydrolase fromSerratia marcescens

(2011) Anne Line Norberg et al.   FEBS LETTERS

Origin of Initial Burst in Activity forTrichoderma reesei endo-Glucanases Hydrolyzing Insoluble Cellulose

(2011) Leigh Murphy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Restructuring the Crystalline Cellulose Hydrogen Bond Network Enhances Its Depolymerization Rate

(2011) Shishir P. S. Chundawat et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Traffic Jams Reduce Hydrolytic Efficiency of Cellulase on Cellulose Surface

(2011) K. Igarashi et al.   SCIENCE

Chitinase Inhibition by Chitobiose and Chitotriose Thiazolines

(2010) James M. Macdonald et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mechanism of initial rapid rate retardation in cellobiohydrolase catalyzed cellulose hydrolysis

(2010) Jürgen Jalak et al.   BIOTECHNOLOGY AND BIOENGINEERING

Signatures of activation parameters reveal substrate-dependent rate determining steps in polysaccharide turnover by a family 18 chitinase

(2010) Henrik Zakariassen et al.   CARBOHYDRATE POLYMERS

Effect of enzyme processivity on the efficacy of a competitive chitinase inhibitor

(2010) Henrik Zakariassen et al.   CARBOHYDRATE POLYMERS

Processivity of Cellobiohydrolases Is Limited by the Substrate

(2010) Mihhail Kurašin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterisation of Specific Activities and Hydrolytic Properties of Cell-Wall-Degrading Enzymes Produced by Trichoderma reesei Rut C30 on Different Carbon Sources

(2009) Bálint Sipos et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Modeling cellulase kinetics on lignocellulosic substrates

(2009) Prabuddha Bansal et al.   BIOTECHNOLOGY ADVANCES

Generating rate equations for complex enzyme systems by a computer-assisted systematic method

(2009) Feng Qi et al.   BMC BIOINFORMATICS

Reducing end-specific fluorescence labeled celluloses for cellulase mode of action

(2009) Riin Velleste et al.   CELLULOSE

Aromatic Residues in the Catalytic Center of Chitinase A fromSerratia marcescensAffect Processivity, Enzyme Activity, and Biomass Converting Efficiency

(2009) Henrik Zakariassen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cloning, expression, and characterization of novel thermostable family 7 cellobiohydrolases

(2008) Sanni P. Voutilainen et al.   BIOTECHNOLOGY AND BIOENGINEERING