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Title
Uracil-DNA Glycosylase UNG Promotes Tet-mediated DNA Demethylation
Authors
Keywords
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Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 291, Issue 2, Pages 731-738
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2015-12-01
DOI
10.1074/jbc.m115.693861
References
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Related references
Note: Only part of the references are listed.- Gadd45a promotes DNA demethylation through TDG
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- Oxidative DNA demethylation mediated by Tet enzymes
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- Enzymatic DNA oxidation: mechanisms and biological significance
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- Tet and TDG Mediate DNA Demethylation Essential for Mesenchymal-to-Epithelial Transition in Somatic Cell Reprogramming
- (2014) Xiao Hu et al. Cell Stem Cell
- Active and Passive Demethylation of Male and Female Pronuclear DNA in the Mammalian Zygote
- (2014) Fan Guo et al. Cell Stem Cell
- Uracil-DNA Glycosylase Is Involved in DNA Demethylation and Required for Embryonic Development in the Zebrafish Embryo
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- TET-mediated oxidation of methylcytosine causes TDG or NEIL glycosylase dependent gene reactivation
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- Notes on the role of dynamic DNA methylation in mammalian development
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- Transient Accumulation of 5-Carboxylcytosine Indicates Involvement of Active Demethylation in Lineage Specification of Neural Stem Cells
- (2014) Lee M. Wheldon et al. Cell Reports
- Crystal Structure of TET2-DNA Complex: Insight into TET-Mediated 5mC Oxidation
- (2013) Lulu Hu et al. CELL
- Genome-wide Analysis Reveals TET- and TDG-Dependent 5-Methylcytosine Oxidation Dynamics
- (2013) Li Shen et al. CELL
- Genome-wide Profiling of 5-Formylcytosine Reveals Its Roles in Epigenetic Priming
- (2013) Chun-Xiao Song et al. CELL
- Tet1 Regulates Adult Hippocampal Neurogenesis and Cognition
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- DNA methylation: roles in mammalian development
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- Base Excision Repair
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- Active demethylation in mouse zygotes involves cytosine deamination and base excision repair
- (2013) Fátima Santos et al. Epigenetics & Chromatin
- AID/APOBEC deaminases disfavor modified cytosines implicated in DNA demethylation
- (2012) Christopher S Nabel et al. Nature Chemical Biology
- Reprogramming DNA methylation in the mammalian life cycle: building and breaking epigenetic barriers
- (2012) S. Seisenberger et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Genomic imprinting in mammals: its life cycle, molecular mechanisms and reprogramming
- (2011) Yufeng Li et al. CELL RESEARCH
- Thymine DNA Glycosylase Can Rapidly Excise 5-Formylcytosine and 5-Carboxylcytosine
- (2011) Atanu Maiti et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes
- (2011) Tian-Peng Gu et al. NATURE
- Deterministic and Stochastic Allele Specific Gene Expression in Single Mouse Blastomeres
- (2011) Fuchou Tang et al. PLoS One
- Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA
- (2011) Y.-F. He et al. SCIENCE
- Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine
- (2011) S. Ito et al. SCIENCE
- 5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming
- (2011) Mark Wossidlo et al. Nature Communications
- Dynamic link of DNA demethylation, DNA strand breaks and repair in mouse zygotes
- (2010) Mark Wossidlo et al. EMBO JOURNAL
- Genome-Wide Reprogramming in the Mouse Germ Line Entails the Base Excision Repair Pathway
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- (2009) M. Tahiliani et al. SCIENCE
- Expression and purification of NEIL3, a human DNA glycosylase homolog
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