Active demethylation in mouse zygotes involves cytosine deamination and base excision repair

FGF Signaling Inhibition in ESCs Drives Rapid Genome-wide Demethylation to the Epigenetic Ground State of Pluripotency

(2013) Gabriella Ficz et al.   Cell Stem Cell

Activation-induced cytidine deaminase auto-activates and triggers aberrant gene expression

(2013) Tomoyasu Isobe et al.   FEBS LETTERS

DNA 5-Methylcytosine Demethylation Activities of the Mammalian DNA Methyltransferases

(2013) Chun-Chang Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AID stabilizes stem-cell phenotype by removing epigenetic memory of pluripotency genes

(2013) Ritu Kumar et al.   NATURE

Mouse Oocyte Methylomes at Base Resolution Reveal Genome-Wide Accumulation of Non-CpG Methylation and Role of DNA Methyltransferases

(2013) Kenjiro Shirane et al.   PLoS Genetics

5-Methylcytosine DNA Demethylation: More Than Losing a Methyl Group

(2012) Don-Marc Franchini et al.   Annual Review of Genetics

A unique regulatory phase of DNA methylation in the early mammalian embryo

(2012) Zachary D. Smith et al.   NATURE

5-Methylcytosine and 5-Hydroxymethylcytosine Spatiotemporal Profiles in the Mouse Zygote

(2012) Juliette Salvaing et al.   PLoS One

Active DNA demethylation by Gadd45 and DNA repair

(2012) Christof Niehrs et al.   TRENDS IN CELL BIOLOGY

Negative Supercoiling Creates Single-Stranded Patches of DNA That Are Substrates for AID–Mediated Mutagenesis

(2012) Jahan-Yar Parsa et al.   PLoS Genetics

Contribution of Intragenic DNA Methylation in Mouse Gametic DNA Methylomes to Establish Oocyte-Specific Heritable Marks

(2012) Hisato Kobayashi et al.   PLoS Genetics

Tet1 and 5-hydroxymethylation

(2011) Hao Wu et al.   CELL CYCLE

AID and partners: for better and (not) for worse

(2011) Sébastien Storck et al.   CURRENT OPINION IN IMMUNOLOGY

Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability

(2011) Daniel Cortázar et al.   NATURE

The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes

(2011) Tian-Peng Gu et al.   NATURE

Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine

(2011) Khursheed Iqbal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetic reprogramming: is deamination key to active DNA demethylation?

(2011) Marta Teperek-Tkacz et al.   REPRODUCTION

Replication-Dependent Loss of 5-Hydroxymethylcytosine in Mouse Preimplantation Embryos

(2011) A. Inoue et al.   SCIENCE

The mechanisms regulating the subcellular localization of AID

(2011) Anne-Marie Patenaude et al.   Nucleus

Dynamic link of DNA demethylation, DNA strand breaks and repair in mouse zygotes

(2010) Mark Wossidlo et al.   EMBO JOURNAL

Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency

(2010) Christian Popp et al.   NATURE

Active DNA demethylation: many roads lead to Rome

(2010) Susan C. Wu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Genome-Wide Reprogramming in the Mouse Germ Line Entails the Base Excision Repair Pathway

(2010) P. Hajkova et al.   SCIENCE

Crosstalk between genetic and epigenetic information through cytosine deamination

(2010) Richard Chahwan et al.   TRENDS IN GENETICS

Active DNA Demethylation Mediated by DNA Glycosylases

(2009) Jian-Kang Zhu   Annual Review of Genetics

DNA Repair in Mammalian Cells

(2009) A. B. Robertson et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Reprogramming towards pluripotency requires AID-dependent DNA demethylation

(2009) Nidhi Bhutani et al.   NATURE

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

(2009) M. Tahiliani et al.   SCIENCE

DNA demethylation by DNA repair

(2009) Mary Gehring et al.   TRENDS IN GENETICS

The Colorful History of Active DNA Demethylation

(2008) Steen K.T. Ooi et al.   CELL

DNA Demethylation in Zebrafish Involves the Coupling of a Deaminase, a Glycosylase, and Gadd45

(2008) Kunal Rai et al.   CELL

DNA double-strand break repair in parental chromatin of mouse zygotes, the first cell cycle as an origin of de novo mutation

(2008) Alwin Derijck et al.   HUMAN MOLECULAR GENETICS

Cyclical DNA methylation of a transcriptionally active promoter

(2008) Raphaël Métivier et al.   NATURE

Transient cyclical methylation of promoter DNA

(2008) Sara Kangaspeska et al.   NATURE