Differential Recognition Preferences of the Three Src Homology 3 (SH3) Domains from the Adaptor CD2-associated Protein (CD2AP) and Direct Association with Ras and Rab Interactor 3 (RIN3)

Targeted sequencing of the Paget's disease associated 14q32 locus identifies several missense coding variants in RIN3 that predispose to Paget's disease of bone

(2015) Mahéva Vallet et al.   HUMAN MOLECULAR GENETICS

Regulation of p130Cas/BCAR1 Expression in Tamoxifen-Sensitive and Tamoxifen-Resistant Breast Cancer Cells by EGR1 and NAB2

(2015) Joerg Kumbrink et al.   NEOPLASIA

Conformational Recognition of an Intrinsically Disordered Protein

(2014) James M. Krieger et al.   BIOPHYSICAL JOURNAL

CD2-associated Protein (CD2AP) Enhances Casitas B Lineage Lymphoma-3/c (Cbl-3/c)-mediated Ret Isoform-specific Ubiquitination and Degradation via Its Amino-terminal Src Homology 3 Domains

(2014) Gina N. Calco et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of the Kidney Slit Diaphragm Adapter Protein CD2-Associated Protein as Determined with Electron Microscopy

(2014) B. D. Adair et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Whole-Exome Sequencing for the Identification of Susceptibility Genes of Kashin–Beck Disease

(2014) Zhenxing Yang et al.   PLoS One

Phenotypic Dissection of Bone Mineral Density Reveals Skeletal Site Specificity and Facilitates the Identification of Novel Loci in the Genetic Regulation of Bone Mass Attainment

(2014) John P. Kemp et al.   PLoS Genetics

Multimeric and differential binding of CIN85/CD2AP with two atypical proline-rich sequences from CD2 and Cbl-b*

(2013) M. Angeles Ceregido et al.   FEBS Journal

FSGS3/CD2AP is a barbed-end capping protein that stabilizes actin and strengthens adherens junctions

(2013) Vivian W. Tang et al.   JOURNAL OF CELL BIOLOGY

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

Distinct Ubiquitin Binding Modes Exhibited by SH3 Domains: Molecular Determinants and Functional Implications

(2013) Jose L. Ortega Roldan et al.   PLoS One

Bridging integrator 1 (BIN1): form, function, and Alzheimer's disease

(2013) Meng-Shan Tan et al.   TRENDS IN MOLECULAR MEDICINE

Novel inhibitors of a Grb2 SH3C domain interaction identified by a virtual screen

(2012) Philip C. Simister et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Adaptor protein complex of FRS2β and CIN85/CD2AP provides a novel mechanism for ErbB2/HER2 protein downregulation

(2012) Yuriko Minegishi et al.   CANCER SCIENCE

Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family

(2012) Panagis Filippakopoulos et al.   CELL

CD2AP/SHIP1 Complex Positively Regulates Plasmacytoid Dendritic Cell Receptor Signaling by Inhibiting the E3 Ubiquitin Ligase Cbl

(2012) M. Bao et al.   JOURNAL OF IMMUNOLOGY

CD2AP Links Cortactin and Capping Protein at the Cell Periphery To Facilitate Formation of Lamellipodia

(2012) J. Zhao et al.   MOLECULAR AND CELLULAR BIOLOGY

Podocyte culture: Tricks of the trade

(2012) LAN NI et al.   NEPHROLOGY

RIN3 Is a Negative Regulator of Mast Cell Responses to SCF

(2012) Christine Janson et al.   PLoS One

Differential Dynamic Engagement within 24 SH3 Domain: Peptide Complexes Revealed by Co-Linear Chemical Shift Perturbation Analysis

(2012) Elliott J. Stollar et al.   PLoS One

Making Ends Meet: The Importance of the N- and C-Termini for the Structure, Stability, and Function of the Third SH3 Domain of CIN85

(2011) D. Philippe et al.   BIOCHEMISTRY

The B-cell antigen receptor signals through a preformed transducer module of SLP65 and CIN85

(2011) Thomas Oellerich et al.   EMBO JOURNAL

Characterization of RIN3 as a Guanine Nucleotide Exchange Factor for the Rab5 Subfamily GTPase Rab31

(2011) Hiroaki Kajiho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Solution structure, dynamics and thermodynamics of the three SH3 domains of CD2AP

(2011) Jose L. Ortega Roldan et al.   JOURNAL OF BIOMOLECULAR NMR

Genome-wide association identifies three new susceptibility loci for Paget's disease of bone

(2011) Omar M E Albagha et al.   NATURE GENETICS

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

(2011) Adam C Naj et al.   NATURE GENETICS

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

(2011) Paul Hollingworth et al.   NATURE GENETICS

Self-Organization and Regulation of Intrinsically Disordered Proteins with Folded N-Termini

(2011) Philip C. Simister et al.   PLOS BIOLOGY

SH3 Domain-Mediated Recruitment of Host Cell Amphiphysins by Alphavirus nsP3 Promotes Viral RNA Replication

(2011) Maarit Neuvonen et al.   PLoS Pathogens

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Novel Insights into the Mechanisms of CIN85 SH3 Domains Binding to Cbl Proteins: Solution-Based Investigations and In Vivo Implications

(2009) Abdessamad Ababou et al.   JOURNAL OF MOLECULAR BIOLOGY

CD2AP mutations are associated with sporadic nephrotic syndrome and focal segmental glomerulosclerosis (FSGS)

(2009) M. Gigante et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Accurate characterization of weak macromolecular interactions by titration of NMR residual dipolar couplings: application to the CD2AP SH3-C:ubiquitin complex

(2009) Jose Luis Ortega-Roldan et al.   NUCLEIC ACIDS RESEARCH

Eukaryotic Protein Domains as Functional Units of Cellular Evolution

(2009) J. Jin et al.   Science Signaling

Distinct Binding Modes of Two Epitopes in Gab2 that Interact with the SH3C Domain of Grb2

(2009) Maria Harkiolaki et al.   STRUCTURE

Bayesian Modeling of the Yeast SH3 Domain Interactome Predicts Spatiotemporal Dynamics of Endocytosis Proteins

(2009) Raffi Tonikian et al.   PLOS BIOLOGY

CD2AP and Cbl-3/Cbl-c Constitute a Critical Checkpoint in the Regulation of Ret Signal Transduction

(2008) C. C. Tsui et al.   JOURNAL OF NEUROSCIENCE

Cell growth, global phosphotyrosine elevation, and c-Met phosphorylation through Src family kinases in colorectal cancer cells

(2008) M. Emaduddin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA