Adaptor protein complex of FRS2β and CIN85/CD2AP provides a novel mechanism for ErbB2/HER2 protein downregulation

Increased levels of the HER1 adaptor protein Ruk l /CIN85 contribute to breast cancer malignancy

(2012) Anatoliy Samoylenko et al.   CARCINOGENESIS

Cell Signaling by Receptor Tyrosine Kinases

(2010) Mark A. Lemmon et al.   CELL

A Dyn2–CIN85 complex mediates degradative traffic of the EGFR by regulation of late endosomal budding

(2010) Barbara Schroeder et al.   EMBO JOURNAL

FRS2β, a potential prognostic gene for non-small cell lung cancer, encodes a feedback inhibitor of EGF receptor family members by ERK binding

(2010) D Iejima et al.   ONCOGENE

FRS2α Regulates Erk Levels to Control a Self-Renewal Target Hes1 and Proliferation of FGF-Responsive Neural Stem/Progenitor Cells

(2010) Takuya Sato et al.   STEM CELLS

Emerging Roles of Ruk/CIN85 in Vesicle-Mediated Transport, Adhesion, Migration and Malignancy

(2010) Serhiy Havrylov et al.   TRAFFIC

The FRS2 family of docking/scaffolding adaptor proteins as therapeutic targets of cancer treatment

(2009) Takuya Sato et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Prominent expression of FRS2β protein in neural cells and its association with intracellular vesicles

(2009) Yuriko Minegishi et al.   FEBS LETTERS

Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS

(2009) Serhiy Havrylov et al.   Proteome Science

Regulation of growth factor signaling by FRS2 family docking/scaffold adaptor proteins

(2008) Noriko Gotoh   CANCER SCIENCE

Visualizing Spatiotemporal Dynamics of Multicellular Cell-Cycle Progression

(2008) Asako Sakaue-Sawano et al.   CELL

Feedback inhibitors of the epidermal growth factor receptor signaling pathways

(2008) Noriko Gotoh   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY