AMP-activated Protein Kinase Suppresses Arachidonate 15-Lipoxygenase Expression in Interleukin 4-polarized Human Macrophages

Mammalian lipoxygenases and their biological relevance

(2015) Hartmut Kuhn et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Metformin Inhibits Monocyte-to-Macrophage Differentiation via AMPK-Mediated Inhibition of STAT3 Activation: Potential Role in Atherosclerosis

(2015) Sathish Babu Vasamsetti et al.   DIABETES

Proresolving Lipid Mediators and Mechanisms in the Resolution of Acute Inflammation

(2014) Christopher D. Buckley et al.   IMMUNITY

Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation

(2014) Jia Xue et al.   IMMUNITY

12/15-Lipoxygenase Regulates the Inflammatory Response to Bacterial Products In Vivo

(2014) V. Dioszeghy et al.   JOURNAL OF IMMUNOLOGY

Adenosine 5'-Monophosphate-Activated Protein Kinase Promotes Macrophage Polarization to an Anti-Inflammatory Functional Phenotype

(2014) D. Sag et al.   JOURNAL OF IMMUNOLOGY

Interleukin-4- and Interleukin-13-Mediated Alternatively Activated Macrophages: Roles in Homeostasis and Disease

(2013) Steven J. Van Dyken et al.   Annual Review of Immunology

15-Lipoxygenase Promotes Chronic Hypoxia–Induced Pulmonary Artery Inflammation via Positive Interaction With Nuclear Factor-κB

(2013) Jing Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences

(2013) F. O. Martinez et al.   BLOOD

AICAR inhibits PPARγ during monocyte differentiation to attenuate inflammatory responses to atherogenic lipids

(2013) Dmitry Namgaladze et al.   CARDIOVASCULAR RESEARCH

AMPKα1 Regulates Macrophage Skewing at the Time of Resolution of Inflammation during Skeletal Muscle Regeneration

(2013) Rémi Mounier et al.   Cell Metabolism

12/15-Lipoxygenase Mediates High-fat Diet-induced Endothelial Tight Junction Disruption and Monocyte Transmigration

(2013) Venkatesh Kundumani-Sridharan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metabolism of inflammation limited by AMPK and pseudo-starvation

(2013) Luke A. J. O'Neill et al.   NATURE

AMPK Activation through Mitochondrial Regulation Results in Increased Substrate Oxidation and Improved Metabolic Parameters in Models of Diabetes

(2013) Yonchu Jenkins et al.   PLoS One

Expression and regulation of 12/15-lipoxygenases in human primary macrophages

(2012) Sophia J.A. Wuest et al.   ATHEROSCLEROSIS

IL-4 and IL-13 employ discrete signaling pathways for target gene expression in alternatively activated monocytes/macrophages

(2012) Ashish Bhattacharjee et al.   FREE RADICAL BIOLOGY AND MEDICINE

AMP-Activated Protein Kinase Restricts IFN-  Signaling

(2012) G. P. Meares et al.   JOURNAL OF IMMUNOLOGY

12/15-Lipoxygenase during the regulation of inflammation, immunity, and self-tolerance

(2012) Stefan Uderhardt et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

12- and 15-lipoxygenases in adipose tissue inflammation

(2012) Banumathi K. Cole et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

AMP-Activated Protein Kinase Suppresses Endothelial Cell Inflammation Through Phosphorylation of Transcriptional Coactivator p300

(2011) Yuan Zhang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

AMP-activated protein kinase--an energy sensor that regulates all aspects of cell function

(2011) D. G. Hardie   GENES & DEVELOPMENT

Hematopoietic AMPK β1 reduces mouse adipose tissue macrophage inflammation and insulin resistance in obesity

(2011) Sandra Galic et al.   JOURNAL OF CLINICAL INVESTIGATION

Molecular enzymology of lipoxygenases

(2010) Igor Ivanov et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

AMP-activated protein kinase inhibits IL-6-stimulated inflammatory response in human liver cells by suppressing phosphorylation of signal transducer and activator of transcription 3 (STAT3)

(2010) A. Nerstedt et al.   DIABETOLOGIA

Alternative Activation of Macrophages: Mechanism and Functions

(2010) Siamon Gordon et al.   IMMUNITY

STAT6 Transcription Factor Is a Facilitator of the Nuclear Receptor PPARγ-Regulated Gene Expression in Macrophages and Dendritic Cells

(2010) Attila Szanto et al.   IMMUNITY

Comprehensive analysis of TLR4-induced transcriptional responses in interleukin 4-primed mouse macrophages

(2010) Carol El Chartouni et al.   IMMUNOBIOLOGY

Macrophage α1 AMP-activated Protein Kinase (α1AMPK) Antagonizes Fatty Acid-induced Inflammation through SIRT1

(2010) Zhenggang Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

12/15-lipoxygenase-derived lipid peroxides control receptor tyrosine kinase signaling through oxidation of protein tyrosine phosphatases

(2010) M. Conrad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alternative activation of macrophages by IL-4 impairs phagocytosis of pathogens but potentiates microbial-induced signalling and cytokine secretion

(2009) A. Varin et al.   BLOOD

12/15-Lipoxygenase Counteracts Inflammation and Tissue Damage in Arthritis

(2009) G. Kronke et al.   JOURNAL OF IMMUNOLOGY

15-Hydroxyeicosatetraenoic Acid Is a Preferential Peroxisome Proliferator-Activated Receptor  /  Agonist

(2009) S. Naruhn et al.   MOLECULAR PHARMACOLOGY

15-Lipoxygenase-2 expression in human macrophages induces chemokine secretion and T cell migration

(2007) Kristina Norén Danielsson et al.   ATHEROSCLEROSIS