12/15-Lipoxygenase during the regulation of inflammation, immunity, and self-tolerance

12/15-Lipoxygenase Regulates the Inflammatory Response to Bacterial Products In Vivo

(2014) V. Dioszeghy et al.   JOURNAL OF IMMUNOLOGY

The 12/15-lipoxygenase pathway counteracts fibroblast activation and experimental fibrosis

(2012) Gerhard Krönke et al.   ANNALS OF THE RHEUMATIC DISEASES

Development of myeloproliferative disease in 12/15-lipoxygenase deficiency

(2012) P. R. Taylor et al.   BLOOD

Oxidized phospholipid signaling in immune cells

(2012) Christopher P Thomas et al.   CURRENT OPINION IN PHARMACOLOGY

12/15-Lipoxygenase Orchestrates the Clearance of Apoptotic Cells and Maintains Immunologic Tolerance

(2012) Stefan Uderhardt et al.   IMMUNITY

Macrophage 12/15 lipoxygenase expression increases plasma and hepatic lipid levels and exacerbates atherosclerosis

(2012) Shunxing Rong et al.   JOURNAL OF LIPID RESEARCH

Cholesteryl ester acyl oxidation and remodeling in murine macrophages: formation of oxidized phosphatidylcholine

(2012) Patrick M. Hutchins et al.   JOURNAL OF LIPID RESEARCH

Esterified eicosanoids: Generation, characterization and function

(2011) Victoria J. Hammond et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Transcriptomic analyses of murine resolution-phase macrophages

(2011) M. J. Stables et al.   BLOOD

Identification of the Orphan G Protein-coupled Receptor GPR31 as a Receptor for 12-(S)-Hydroxyeicosatetraenoic Acid

(2011) Yande Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

15-lipoxygenase-1 exerts its tumor suppressive role by inhibiting nuclear factor-kappa B via activation of PPAR gamma

(2011) I. Cimen et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Nutrigenetic Disruption of Inflammation-Resolution Homeostasis and Atherogenesis

(2011) Aksam J. Merched et al.   Journal of Nutrigenetics and Nutrigenomics

Novel Lipid Mediators and Resolution Mechanisms in Acute Inflammation

(2010) Charles N. Serhan   AMERICAN JOURNAL OF PATHOLOGY

Differential expression and localization of 12/15 lipoxygenases in adipose tissue in human obese subjects

(2010) Anca D. Dobrian et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Identification of a Novel Macrophage Phenotype That Develops in Response to Atherogenic Phospholipids via Nrf2

(2010) Alexandra Kadl et al.   CIRCULATION RESEARCH

Saturated-efferocytosis generates pro-resolving CD11blow macrophages: Modulation by resolvins and glucocorticoids

(2010) Sagie Schif-Zuck et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Increased Nuclear Apoptosis-Inducing Factor after Transient Focal Ischemia: A 12/15-Lipoxygenase-dependent Organelle Damage Pathway

(2010) Stefanie Pallast et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Anti-Inflammatory Role of the Murine Formyl-Peptide Receptor 2: Ligand-Specific Effects on Leukocyte Responses and Experimental Inflammation

(2010) Neil Dufton et al.   JOURNAL OF IMMUNOLOGY

Resolution of Inflammation in Murine Autoimmune Arthritis Is Disrupted by Cyclooxygenase-2 Inhibition and Restored by Prostaglandin E2-Mediated Lipoxin A4 Production

(2010) M. M. Y. Chan et al.   JOURNAL OF IMMUNOLOGY

The role of defective clearance of apoptotic cells in systemic autoimmunity

(2010) Luis E. Muñoz et al.   Nature Reviews Rheumatology

Old and new generation lipid mediators in acute inflammation and resolution

(2010) Melanie J. Stables et al.   PROGRESS IN LIPID RESEARCH

Functional and pathological roles of the 12- and 15-lipoxygenases

(2010) Anca D. Dobrian et al.   PROGRESS IN LIPID RESEARCH

Generation and Biological Activities of Oxidized Phospholipids

(2009) Valery N. Bochkov et al.   ANTIOXIDANTS & REDOX SIGNALING

Epigenetic regulation of dendritic cell differentiation and function by oxidized phospholipids

(2009) S. Bluml et al.   BLOOD

Lipoprotein Accumulation in Macrophages via Toll-Like Receptor-4–Dependent Fluid Phase Uptake

(2009) Soo-Ho Choi et al.   CIRCULATION RESEARCH

Phosphatidylethanolamine-esterified Eicosanoids in the Mouse

(2009) Alwena H. Morgan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cardiac 12/15 lipoxygenase–induced inflammation is involved in heart failure

(2009) Yosuke Kayama et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Improved Survival and Reduced Vascular Permeability by Eliminating or Blocking 12/15-Lipoxygenase in Mouse Models of Acute Lung Injury (ALI)

(2009) A. Zarbock et al.   JOURNAL OF IMMUNOLOGY

12/15-Lipoxygenase Counteracts Inflammation and Tissue Damage in Arthritis

(2009) G. Kronke et al.   JOURNAL OF IMMUNOLOGY

12/15-Lipoxygenase targets neuronal mitochondria under oxidative stress

(2009) Stefanie Pallast et al.   JOURNAL OF NEUROCHEMISTRY

12/15-Lipoxygenase Is Required for the Early Onset of High Fat Diet-Induced Adipose Tissue Inflammation and Insulin Resistance in Mice

(2009) Dorothy D. Sears et al.   PLoS One

Targeted lipidomics reveals mPGES-1-PGE2 as a therapeutic target for multiple sclerosis

(2009) Y. Kihara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

12-Lipoxygenase-knockout mice are resistant to inflammatory effects of obesity induced by western diet

(2008) Craig S. Nunemaker et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Mice Lacking 12/15-Lipoxygenase Have Attenuated Airway Allergic Inflammation and Remodeling

(2008) Cecilia K. Andersson et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Multi-Hit Inhibition of Circulating and Cell-Associated Components of the Toll-Like Receptor 4 Pathway by Oxidized Phospholipids

(2008) Elena von Schlieffen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Atherosclerosis: evidence for impairment of resolution of vascular inflammation governed by specific lipid mediators

(2008) Aksam J. Merched et al.   FASEB JOURNAL

Cholesteryl Ester Hydroperoxides Are Biologically Active Components of Minimally Oxidized Low Density Lipoprotein

(2008) Richard Harkewicz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protecting Against Cerebrovascular Injury

(2008) Guang Jin et al.   STROKE