Determination of cleavage site of Reelin between its sixth and seventh repeat and contribution of meprin metalloproteases to the cleavage

Importance of Reelin C-Terminal Region in the Development and Maintenance of the Postnatal Cerebral Cortex and Its Regulation by Specific Proteolysis

(2015) T. Kohno et al.   JOURNAL OF NEUROSCIENCE

Meprin α and meprin β: Procollagen proteinases in health and disease

(2015) Johannes Prox et al.   MATRIX BIOLOGY

Reelin Signaling Specifies the Molecular Identity of the Pyramidal Neuron Distal Dendritic Compartment

(2014) Justine V. Kupferman et al.   CELL

Meprin Metalloproteases Inactivate Interleukin 6

(2014) Timothy R. Keiffer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cleavage within Reelin Repeat 3 Regulates the Duration and Range of the Signaling Activity of Reelin Protein

(2014) Mari Koie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extracellular proteolysis of reelin by tissue plasminogen activator following synaptic potentiation

(2014) J.H. Trotter et al.   NEUROSCIENCE

Reelin delays amyloid-beta fibril formation and rescues cognitive deficits in a model of Alzheimer’s disease

(2014) Lluís Pujadas et al.   Nature Communications

The metalloproteases meprin α and meprin β: unique enzymes in inflammation, neurodegeneration, cancer and fibrosis

(2013) Claudia Broder et al.   BIOCHEMICAL JOURNAL

TIMP-1 inhibits the proteolytic processing of Reelin in experimental epilepsy

(2013) Stefanie Tinnes et al.   FASEB JOURNAL

Reduced Reelin Expression Accelerates Amyloid-  Plaque Formation and Tau Pathology in Transgenic Alzheimer's Disease Mice

(2013) S. Kocherhans et al.   JOURNAL OF NEUROSCIENCE

Decisive role of Reelin signaling during early stages of Alzheimer’s disease

(2013) D. Krstic et al.   NEUROSCIENCE

Metalloproteases meprin   and meprin   are C- and N-procollagen proteinases important for collagen assembly and tensile strength

(2013) C. Broder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS-4) cleaves Reelin in an isoform-dependent manner

(2012) Arisa Hisanaga et al.   FEBS LETTERS

The Metalloprotease Meprin β Generates Amino Terminal-truncated Amyloid β Peptide Species

(2012) Jessica Bien et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The involvement of Reelin in neurodevelopmental disorders

(2012) Timothy D. Folsom et al.   NEUROPHARMACOLOGY

Regulated Proteolytic Processing of Reelin through Interplay of Tissue Plasminogen Activator (tPA), ADAMTS-4, ADAMTS-5, and Their Modulators

(2012) Dimitrije Krstic et al.   PLoS One

Metalloprotease Meprin β Generates Nontoxic N-terminal Amyloid Precursor Protein Fragmentsin Vivo

(2011) Tamara Jefferson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Emerging topics in Reelin function

(2010) Eckart Förster et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Epileptiform activity interferes with proteolytic processing of Reelin required for dentate granule cell positioning

(2010) Stefanie Tinnes et al.   FASEB JOURNAL

Processing of Procollagen III by Meprins: New Players in Extracellular Matrix Assembly?

(2010) Daniel Kronenberg et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Migration, early axonogenesis, and Reelin-dependent layer-forming behavior of early/posterior-born Purkinje cells in the developing mouse lateral cerebellum

(2010) Takaki Miyata et al.   Neural Development

Mechanism and significance of specific proteolytic cleavage of Reelin

(2009) Shiori Kohno et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Downregulation of Functional Reelin Receptors in Projection Neurons Implies That Primary Reelin Action Occurs atEarly/Premigratory Stages

(2009) T. Uchida et al.   JOURNAL OF NEUROSCIENCE

C-terminal region-dependent change of antibody-binding to the Eighth Reelin repeat reflects the signaling activity of Reelin

(2009) Takao Kohno et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Splicing variations in the ligand-binding domain of ApoER2 results in functional differences in the binding properties to Reelin

(2009) Terumasa Hibi et al.   NEUROSCIENCE RESEARCH

Reelin signaling antagonizes  -amyloid at the synapse

(2009) M. S. Durakoglugil et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prointerleukin-18 Is Activated by Meprin βin Vitroandin Vivoin Intestinal Inflammation

(2008) Sanjita Banerjee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY