Article
Psychology
Maria V. Stuckenberg, Erich Schroeger, Andreas Widmann
Summary: Research has found that visual cues misleading auditory expectations can trigger incongruency response in auditory event-related brain potentials, possibly due to a mismatch between auditory sensory expectations activated by visual predictive information and actual sensory input. The incongruency effect is more likely to occur with asynchronous presentation of visual-auditory combinations, suggesting a potential bimodal feature mismatch when violation of the visual-auditory relationship occurs.
ATTENTION PERCEPTION & PSYCHOPHYSICS
(2021)
Article
Multidisciplinary Sciences
Jacques Pesnot Lerousseau, Cesare Parise, Marc O. Ernst, Virginie van Wassenhove
Summary: In this study, the authors demonstrate the existence of neural mechanisms in the human brain that mediate the integration and segregation of multisensory information. The Multisensory Correlation Detector model explains well the behavioral judgments of causal inference and temporal order. The results suggest the presence of multisensory correlation detectors in the brain, which strongly influence causal inference based on temporal correlation of multisensory signals.
NATURE COMMUNICATIONS
(2022)
Article
Neurosciences
Malgorzata Wislowska, Wolfgang Klimesch, Ole Jensen, Christine Blume, Manuel Schabus
Summary: Recent research has found that a wide range of cognitive operations are preserved during sleep in humans. This challenges scientists to understand the functions and mechanisms of these processes, which have mainly been studied in awake individuals. In this study, the focus is on the dynamic changes of brain oscillations and connectivity patterns in response to environmental stimulation during non-REM sleep. The results show that aurally presented names were processed and differentiated by neurons across the wake-sleep spectrum. EEG and MEG signals recorded simultaneously revealed two distinct clusters of oscillatory power increase in response to the stimuli. This study discusses the possible roles of different oscillations during non-REM sleep and aims to develop a unified theory of brain rhythms and their functions during sleep.
JOURNAL OF NEUROSCIENCE
(2022)
Article
Engineering, Biomedical
Alain de Cheveigne, Malcolm Slaney, Soren A. Fuglsang, Jens Hjortkjaer
Summary: This study focuses on analyzing brain responses evoked by auditory stimuli through model fitting, providing insights into perceptual processes and serving as references for devices like BCIs. By using a match-mismatch task, models of varying complexity were compared to methods in literature, showcasing state-of-the-art performance. The MM task allows evaluation of stimulus-response models at high accuracy limits, offering an attractive alternative to commonly used auditory attention detection tasks.
JOURNAL OF NEURAL ENGINEERING
(2021)
Article
Neurosciences
Sam van Bijnen, Lauri Parkkonen, Tiina Parviainen
Summary: Sensory processing during development is crucial for the cognitive functions in children. This study found that auditory cortical activity in children predicts performance in inhibition tasks and is correlated with the variability of behavioral response time. The brain mechanisms for auditory-based cognitive tasks differ between children and adults.
Article
Neurosciences
Sam van Bijnen, Joona Muotka, Tiina Parviainen
Summary: Adults and children have different cortical auditory activation, which is relevant for cognitive performance in children, specifically inhibitory control. However, it is uncertain whether these differences result in functional differences in response inhibition between adults and children. Using M/EEG, we recorded auditory responses and found divergent brain-behavior associations between adults and children. Adults show negative associations between auditory cortical responses and inhibitory performance, while these associations are not significant in children or stronger responses are beneficial. There are also differences in brain responses between adults and children, with adults showing a shift in peak activation to frontomedial areas and children displaying prolonged obligatory responses in the auditory cortex.
HUMAN BRAIN MAPPING
(2023)
Article
Food Science & Technology
Angelo Torrente, Laura Pilati, Salvatore Di Marco, Simona Maccora, Paolo Alonge, Lavinia Vassallo, Antonino Lupica, Serena Coppola, Cecilia Camarda, Nadia Bolognini, Filippo Brighina
Summary: This study found that multisensory integration is modified in chronic migraine, and onabotulinumtoxinA is effective in preventing chronic migraine and restoring multisensory processing.
Article
Computer Science, Artificial Intelligence
Huanqing Zhang, Jun Xie, Yi Xiao, Guiling Cui, Xinyu Zhu, Guanghua Xu, Qing Tao, Yuzhe Yang, Zhiyuan Ren, Min Li
Summary: This study analyzed the effects of steady-state auditory-visual motion stimuli on EEG and found that synchronous and asynchronous stimuli can enhance brain responses and activate areas involved in auditory and visual integration. Moreover, asynchronous stimuli activated the Anterior Cingulate region, indicating its involvement in conflicting processing of steady-state auditory-visual motion information.
EXPERT SYSTEMS WITH APPLICATIONS
(2024)
Article
Neurosciences
Xiao Han, Jinghong Xu, Song Chang, Les Keniston, Liping Yu
Summary: This study investigates how sensory processing in sensory cortices is modulated by cross-modal interaction during perceptual tasks. The researchers recorded neural responses in the primary auditory cortex of rats performing discrimination tasks with audiovisual or unisensory cues. They found that cross-modal representation in auditory cortices varies with task contexts, with a significant increase in visually evoked responses during tasks with an audiovisual cue associated with reward. Additionally, associative learning seemed to have a plastic effect on multisensory enhancement in the auditory cortex. These findings suggest that multisensory processing in sensory cortices is not static and can be substantially enhanced by cross-modal interaction.
Article
Radiology, Nuclear Medicine & Medical Imaging
Odile Feys, Pierre Corvilain, Alec Aeby, Claudine Sculier, Niall Holmes, Matthew Brookes, Serge Goldman, Vincent Wens, Xavier De Tiege, Florence Christiaens
Summary: This study compared the effectiveness of cryogenic and on-scalp MEG in detecting and localizing focal interictal epileptiform discharges (IEDs) in children with epilepsy. The results showed that on-scalp MEG had higher IED amplitudes and signal-to-noise ratios compared to cryogenic MEG, and the localization value was similar between the two modalities.
Article
Neurosciences
Diane Rekow, Jean-Yves Baudouin, Karine Durand, Arnaud Leleu
Summary: Visual categorization is the brain's ability to respond rapidly to certain category of inputs, and it might be influenced by odors. The experiment found that odor can enhance the response to ambiguous face-like objects, but it has no significant effect on other category-selective responses or general visual response. These findings suggest that the brain actively uses cues from different senses to categorize visual inputs, and olfaction can disambiguate visual information effectively.
Article
Neurosciences
Corrina Maguinness, Katharina von Kriegstein
Summary: Recognition of voice identity is supported by visual mechanisms, with a face-benefit increasing in noisy listening conditions. In high-noise situations, the right posterior superior temporal sulcus is involved in processing dynamic facial cues for recognition of face-learned speakers.
HUMAN BRAIN MAPPING
(2021)
Article
Neurosciences
Anna-Katharina R. Bauer, Freek van Ede, Andrew J. Quinn, Anna C. Nobre
Summary: This study used human EEG to investigate the cross-modal influences of continuous auditory FM sound on visual perception and cortical activity. The research found systematic fluctuations in perceptual discrimination of brief visual stimuli in line with the phase of the FM sound, and demonstrated a relationship between rhythmic modulation in visual perception and neural activity in visual areas.
JOURNAL OF NEUROSCIENCE
(2021)
Article
Psychology, Biological
Utku Kaya, Hulusi Kafaligonul
Summary: The integration of information from different senses, particularly audiovisual interactions, plays a crucial role in our perception. Previous studies have shown that even task-irrelevant information from a secondary modality can influence the detection and discrimination of a primary target, with changes in behavioral reaction times being significantly associated with the timing of auditory and visual stimuli. Additionally, modulations in evoked activities over specific brain regions within a specific time range were found to correlate with changes in reaction times, emphasizing the functional link between audiovisual interactions and early sensory processing.
Article
Multidisciplinary Sciences
Maryam Honari-Jahromi, Brea Chouinard, Esti Blanco-Elorrieta, Liina Pylkkanen, Alona Fyshe
Summary: Despite the maturity of neuroscience research on composition, the evolution of stored semantic representations during composition remains poorly understood. New decoding techniques have allowed researchers to train models to recognize representations in one context or time-point and assess their accuracy in another. The study found that noun representations were generally more decodable than adjective representations, with nouns maintaining consistency across trials and over time in phrases. Adjective representations, on the other hand, did not show similar consistency across isolated and phrasal contexts.
Article
Neurosciences
Moritz Herbert Albrecht Koehler, Nathan Weisz
Summary: This study provides evidence that attention can modulate the rhythmic activity of the auditory system by influencing the functioning of sensory receptors. It was found that intermodal and interaural attention have different effects on auditory processing, with intermodal attention modulating activity level and interaural attention modulating timing.
JOURNAL OF COGNITIVE NEUROSCIENCE
(2023)
Article
Endocrinology & Metabolism
Helge Jorn Zollner, Thomas A. A. Thiel, Nur-Deniz Fuellenbach, Markus S. Joerdens, Sinyeob Ahn, Lena M. M. Wilms, Alexandra Ljimani, Dieter Haeussinger, Markus Butz, Hans-Joerg Wittsack, Alfons Schnitzler, Georg Oeltzschner
Summary: Using GABA-edited MRS, this study investigates metabolic abnormalities in the cerebello-thalamo-cortical system of HE patients, finding changes in GABA+ levels in the cerebellum and motor cortex that are closely linked to disease severity, CFF, motor performance, and blood ammonia levels.
METABOLIC BRAIN DISEASE
(2023)
Article
Clinical Neurology
Serge Pinto, Adelheid Nebel, Jorn Rau, Robert Espesser, Pauline Maillochon, Oliver Niebuhr, Paul Krack, Tatiana Witjas, Alain Ghio, Marie-Charlotte Cuartero, Lars Timmermann, Alfons Schnitzler, Helke Hesekamp, Niklaus Meier, Julia Muellner, Thomas D. Haelbig, Bettina Moeller, Steffen Paschen, Laura Paschen, Jens Volkmann, Michael T. Barbe, Gereon R. Fink, Johannes Becker, Paul Reker, Andrea A. Kuehn, Gerd-Helge Schneider, Valerie Fraix, Eric Seigneuret, Andrea Kistner, Olivier Rascol, Christine Brefel-Courbon, Fabienne Ory-Magne, Christian J. Hartmann, Lars Wojtecki, Anne Fradet, David Maltete, Philippe Damier, Severine Le Dily, Friederike Sixel-Doering, Petra Benecke, Daniel Weiss, Tobias Waechter, Marcus O. Pinsker, Jean Regis, Stephane Thobois, Gustavo Polo, Jean-Luc Houeto, Andreas Hartmann, Karina Knudsen, Marie Vidailhet, Michael Schuepbach, Gunther Deuschl
Summary: This study compared speech intelligibility assessment and other outcomes between subthalamic nucleus deep brain stimulation (STN-DBS) and best medical treatment (BMT) in early-stage Parkinson's disease patients over a 2-year period. The results showed no significant differences in speech intelligibility and patient-reported outcomes between the STN-DBS and BMT groups, but there was a trend towards worsening in both groups.
MOVEMENT DISORDERS
(2023)
Article
Multidisciplinary Sciences
Carlos Trenado, Matthias Boschheidgen, Karim N'Diaye, Alfons Schnitzler, Luc Mallet, Lars Wojtecki
Summary: Deep brain stimulation of the subthalamic nucleus (STN-DBS) is effective in treating motor symptoms in Parkinson's disease (PD), but its impact on high cognitive processes such as metacognition remains unclear. This study found no significant effect of STN-DBS on reversal learning (RL) or metacognition.
SCIENTIFIC REPORTS
(2023)
Article
Neuroimaging
Matthias Sure, Sean Mertiens, Jan Vesper, Alfons Schnitzler, Esther Florin
Summary: The stun effect from deep brain stimulation (DBS) electrodes in Parkinson's disease (PD) patients can temporarily improve motor symptoms. However, the network changes induced by the stun effect have not been well characterized. This study investigated whether the DBS-related stun effect also modulated resting-state networks (RSNs) and found that it alters different functional RSNs throughout the brain.
NEUROIMAGE-CLINICAL
(2023)
Article
Neurosciences
Jannes Freiberg, Lukas Lang, Christian Kaernbach, Julian Keil
Summary: By using non-invasive surface electrodes, researchers have successfully measured the ongoing neural activity of living planarians, revealing a 1/f(x) power spectrum and its sensitivity to changes in lighting conditions. This study provides a foundation for further investigation into the cognitive abilities of simple nervous systems.
Editorial Material
Clinical Neurology
Bahne H. Bahners, Rachel K. Spooner, Christian J. Hartmann, Alfons Schnitzler, Esther Florin
Article
Psychology, Biological
Annekathrin Weise, Thomas Hartmann, Fabrice Parmentier, Nathan Weisz, Philipp Ruhnau
Summary: The study found that the sudden siren of an ambulance can interfere with people's attention and performance. The experiment showed that when the target and the distracting sound occurred on the same side, individuals responded faster, indicating a spatial shift of attention. The results of the brainwave data also supported this finding, suggesting that spatial attention bias influences the impact of distracting sounds.
Article
Neurosciences
Rachel K. Spooner, Bahne H. Bahners, Alfons Schnitzler, Esther Florin
Summary: Research shows that optimal contact orientations in subthalamic deep brain stimulation can lead to larger cortical responses and smoother hand movements in patients with Parkinson's disease. These findings have clinical implications for optimizing DBS parameter settings to alleviate motor symptoms.
NPJ PARKINSONS DISEASE
(2023)
Article
Psychology, Experimental
Julia Henkel, Christian Hartmann, Valentina Niccolai, Ruben van de Vijver, Alfons Schnitzler, Katja Biermann-Ruben
Summary: Parkinson's disease not only affects the motor system, but also language abilities, particularly syntactic subordination. This study found that patients with Parkinson's disease showed a significant reduction in subordinating structures compared to a healthy control group, while the number of non-embedding sentences remained unaffected. Additionally, the medication status of levodopa did not have a significant effect on language abilities. These results suggest a contribution of the basal ganglia to language processing, which is not dopamine dependent.
Article
Neurosciences
Frederick Benjamin Junker, Tobias Schmidt-Wilcke, Alfons Schnitzler, Joachim Lange
Summary: This study explores the nonlexical components of language decoding using Morse code as a model. Magnetoencephalography was employed to investigate the brain regions associated with Morse code decoding and word comprehension. The findings provide insights into the neural mechanisms underlying language decoding.
HUMAN BRAIN MAPPING
(2023)
Article
Psychology, Biological
Juliane Schubert, Nina Suess, Nathan Weisz
Summary: Predictive processing theories describe the brain as a prediction machine and explain various cognitive functions. It is known that abnormal prediction tendencies are important for psychiatric disorders. In this study, we quantified the generalization of individual prediction tendencies across modalities and found that the tendency to anticipate sensory features of high probability does not correlate between auditory and visual modalities. Our findings challenge the assumption of a unified trait for prediction tendency.
Article
Clinical Neurology
Barbara Ladisich, Stefan Rampp, Eugen Trinka, Nathan Weisz, Christoph Schwartz, Theo Kraus, Camillo Sherif, Franz Marhold, Gianpaolo Demarchi
Summary: By analyzing the network topology of neurooncological patients, it was found that the network topology in brain tumor patients is altered, but there is no consensus on the pattern of these changes and evidence on potential drivers is lacking.
THERAPEUTIC ADVANCES IN NEUROLOGICAL DISORDERS
(2023)
Review
Neurosciences
Lisa Reisinger, Gianpaolo Demarchi, Nathan Weisz
Summary: This review introduces the underlying causes and altered neural activity of tinnitus in different brain regions, and discusses the methods and limitations of using MEG for tinnitus research. The authors suggest novel approaches and frameworks to gain a more comprehensive understanding of tinnitus and its underlying processes.
JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY
(2023)
Article
Clinical Neurology
Marius Kroesche, Silja Kannenberg, Markus Butz, Christian J. Hartmann, Esther Florin, Alfons Schnitzler, Jan Hirschmann
Summary: This study identified spectral slowing, particularly affecting the frontal beta oscillations, in patients with atypical parkinsonian syndromes. This finding may serve as an electrophysiological marker for the differential diagnosis of Parkinson's disease in the future.
MOVEMENT DISORDERS
(2023)
Article
Behavioral Sciences
Radwa H. Lutfy, Sherine Abdel Salam, Haitham S. Mohammed, Marwa M. Shakweer, Amina E. Essawy
Summary: Insufficient sleep is associated with impaired hypothalamic activity and declined attentional performance. This study found that near-infrared (NIR) laser therapy can alleviate the effects of sleep deprivation on the hypothalamus, enhance antioxidant status, suppress neuroinflammation, and regulate cellular activity.
BEHAVIOURAL BRAIN RESEARCH
(2024)
Article
Behavioral Sciences
Durmus Ali Aslanlar, Emin Fatih Visneci, Mehmet Oz, K. Esra Nurullahoglu Atalik
Summary: Mood disorders caused by chemotherapy have become more important as cancer patients' survival increases. This study used methotrexate to induce mood disorders in rats and found that treatment with the antioxidant N-acetylcysteine (NAC) can alleviate anxiety and depression-like behaviors, increase antioxidant capacity, reduce oxidative stress and inflammatory response, and regulate brain chemistry. The findings suggest that NAC treatment could be an effective strategy in revising the treatment for individuals suffering from chemotherapy-induced mood disorders.
BEHAVIOURAL BRAIN RESEARCH
(2024)
Article
Behavioral Sciences
Yunfan Zhang, Yunbin Zhang, Zhuangfei Chen, Ping Ren, Yu Fu
Summary: This study systematically investigated the effects of extremely low intensity HF-rTMS on cognition in mice and found that 40 Hz rTMS significantly impaired exploratory behavior and spatial memory at both 10 mT and 1 mT conditions. Additionally, 40 Hz stimulation had remarkably different effects on exploratory behavior depending on intensity, compared to 10 Hz stimulation.
BEHAVIOURAL BRAIN RESEARCH
(2024)
Article
Behavioral Sciences
Xuan Xuan, Guangling Zheng, Wenjia Zhu, Qionghua Sun, Yawei Zeng, Juan Du, Xusheng Huang
Summary: This study examines the functional characteristics of the cerebellum in individuals with sALS and their correlation with clinical data. The results show changes in both local and global functional connectivity in the cerebellum of sALS patients, suggesting a pathophysiological role of the cerebellum in sALS.
BEHAVIOURAL BRAIN RESEARCH
(2024)
Article
Behavioral Sciences
Mehdi Rezaei, Mohammad Mahdi Shariat Bagheri
Summary: This study examined the efficacy of tDCS for PTSD and related symptoms, as well as the factors that may predict response to tDCS. The results showed that tDCS had a positive effect in reducing symptoms of PTSD, depression, anxiety, and anhedonia. The severity of symptoms at baseline may also predict the response to tDCS.
BEHAVIOURAL BRAIN RESEARCH
(2024)
Article
Behavioral Sciences
Huimin Wu, Yiqun Guo, Yaoyao Zhang, Le Zhao, Cheng Guo
Summary: Aggression can have serious consequences, but little is known about its personality and neurological origins in children. This study investigated the relationship between self-esteem, aggression, and brain structure in healthy children, and found that self-esteem was negatively associated with aggression. The study also revealed that increased cortical thickness in certain brain areas may be a potential mechanism linking low self-esteem to aggression in children.
BEHAVIOURAL BRAIN RESEARCH
(2024)
Article
Behavioral Sciences
Xinmei Deng, Kexin Chen, Xiaoming Chen, Lin Zhang, Mingping Lin, Xiaoqing Li, Qiufeng Gao
Summary: Parental involvement affects the relationship and communication between parents and adolescents. This study found that high parental involvement is associated with stronger brain-to-brain synchrony during shared positive emotional experiences, while low parental involvement is associated with stronger synchrony during shared negative emotional experiences.
BEHAVIOURAL BRAIN RESEARCH
(2024)
Article
Behavioral Sciences
Xin Deng, I. -Shuo Huang, Kourtlin Williams, Marcy L. Wainwright, Paul Zimba, Riccardo Mozzachiodi
Summary: Food deprivation can lead to neurological dysfunctions, including memory impairment. This study used Aplysia as an animal model to investigate the memory deficits caused by prolonged food deprivation. The results showed that 14 days of food deprivation decreased the level of 5-HT in the hemolymph, which contributed to the lack of sensitization and its cellular correlates. However, exogenous application of 5-HT partially induced sensitization in the food deprived animals.
BEHAVIOURAL BRAIN RESEARCH
(2024)
Article
Behavioral Sciences
Ihori Kobayashi, Patrick A. Forcelli
Summary: The study found that intervention with the dual orexin receptor antagonist suvorexant did not have the expected effects on extinction memory and sleep. Higher percentages of REM sleep were associated with poorer extinction memory recall and stronger fear responses. Additionally, the fear extinction training protocol used in this study did not lead to complete fear extinction.
BEHAVIOURAL BRAIN RESEARCH
(2024)
Article
Behavioral Sciences
Jiyan Xu, Xinlu Chen, Shuai Liu, Ziqi Wei, Minhui Xu, Linhao Jiang, Xue Han, Liangyu Peng, Xiaoping Gu, Tianjiao Xia
Summary: This study investigated the effects of nicotinamide mononucleotide (NMN) on oxidative stress and cognitive function in postoperative cognitive dysfunction (POCD) mice. The results showed that NMN pretreatment reduced oxidative stress damage and alleviated cognitive impairment in POCD mice.
BEHAVIOURAL BRAIN RESEARCH
(2024)
Article
Behavioral Sciences
Song Liu, Qiang Wu, Liyue Wang, Cong Xing, Junrui Guo, Baicao Li, Hongpeng Ma, Hao Zhong, Mi Zhou, Shibo Zhu, Rusen Zhu, Guangzhi Ning
Summary: In this study, a systematic assessment indicator was developed to objectively evaluate hindlimb motor function recovery in rats after thoracic contusion SCI. By screening CatWalk XT gait parameters and using exploratory factor analysis, 38 suitable parameters for assessing motor function were identified. A reliable Coordinated Function Index (CFI) was proposed based on these parameters and simplified for improved assessment efficacy.
BEHAVIOURAL BRAIN RESEARCH
(2024)
Article
Behavioral Sciences
Kyosuke Shiga, Shota Miyaguchi, Yasuto Inukai, Naofumi Otsuru, Hideaki Onishi
Summary: This study aimed to investigate the effects of transcranial alternating current stimulation (tACS) on microscale learning in implicit motor tasks. Contrary to expectations, the results showed that the stimulation protocol had no significant effects on microscale learning, revealing a novel aspect of microscale learning in implicit motor tasks.
BEHAVIOURAL BRAIN RESEARCH
(2024)
Article
Behavioral Sciences
Cahide Aslan, Rahime Aslankoc, Ozlem Ozmen, Buse Nur Suluk, Oguzhan Kavrik, Nurhan Gumral
Summary: This study examined the negative effects of high fructose corn syrup on prefrontal cortex damage in adolescent rats, as well as the protective role of vitamin D.
BEHAVIOURAL BRAIN RESEARCH
(2024)
Article
Behavioral Sciences
Matin Baghani, Arad Bolouri-Roudsari, Reyhaneh Askari, Abbas Haghparast
Summary: The study suggests that the orexinergic system in the dentate gyrus region of the brain may act as an endogenous pain control system and a potential target for treating stress-related disorders.
BEHAVIOURAL BRAIN RESEARCH
(2024)
Article
Behavioral Sciences
Sen Zhou, Yang Liu, Binbin Xue, Peigen Yuan
Summary: This study confirmed that low-dose Esketamine alleviates LPS-induced depressive symptoms by regulating the GSK-3 beta/NLRP3 pathway. Appropriate doses of Esketamine are essential for the treatment of depression in the clinical setting.
BEHAVIOURAL BRAIN RESEARCH
(2024)
