Molecular and cellular mechanisms of macrophage survival in atherosclerosis

Everolimus Triggers Cytokine Release by Macrophages

(2012) Wim Martinet et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Fractalkine: A Survivor's Guide

(2012) Gemma E. White et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Bcl-x Inactivation in Macrophages Accelerates Progression of Advanced Atherosclerotic Lesions in Apoe −/− Mice

(2012) Andrew I.U. Shearn et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Toll-like receptor 7 stimulation by imiquimod induces macrophage autophagy and inflammation in atherosclerotic plaques

(2012) Inge Meyer et al.   BASIC RESEARCH IN CARDIOLOGY

Therapeutic strategies to deplete macrophages in atherosclerotic plaques

(2012) Inge De Meyer et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Autophagy Links Inflammasomes to Atherosclerotic Progression

(2012) Babak Razani et al.   Cell Metabolism

Macrophage Autophagy Plays a Protective Role in Advanced Atherosclerosis

(2012) Xianghai Liao et al.   Cell Metabolism

Autophagy genes function sequentially to promote apoptotic cell corpse degradation in the engulfing cell

(2012) Wei Li et al.   JOURNAL OF CELL BIOLOGY

Co-Stimulation of PAFR and CD36 Is Required for oxLDL-Induced Human Macrophages Activation

(2012) Francisco J. O. Rios et al.   PLoS One

Phenotypic and Functional Heterogeneity of Macrophages and Dendritic Cell Subsets in the Healthy and Atherosclerosis-Prone Aorta

(2012) Matthew J. Butcher et al.   Frontiers in Physiology

Autophagy in Atherosclerosis

(2011) Dorien M. Schrijvers et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Monocyte and Macrophage Dynamics During Atherogenesis

(2011) Klaus Ley et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

OxLDL and macrophage survival: essential and oxygen-independent involvement of the Hif-pathway

(2011) David M. Poitz et al.   BASIC RESEARCH IN CARDIOLOGY

Necrotic cell death in atherosclerosis

(2011) Wim Martinet et al.   BASIC RESEARCH IN CARDIOLOGY

Requirement for non-regulated, constitutive calcium influx in macrophage survival signaling

(2011) Jean-Yves Tano et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

OxLDL-mediated survival of macrophages does not require LDL internalization or signalling by major pattern recognition receptors

(2011) Maziar Riazy et al.   Biochemistry and Cell Biology

Toso regulates the balance between apoptotic and nonapoptotic death receptor signaling by facilitating RIP1 ubiquitination

(2011) X.-H. Nguyen et al.   BLOOD

Pharmacological modulation of cell death in atherosclerosis: a promising approach towards plaque stabilization?

(2011) Wim Martinet et al.   BRITISH JOURNAL OF PHARMACOLOGY

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

Macrophages in the Pathogenesis of Atherosclerosis

(2011) Kathryn J. Moore et al.   CELL

Autophagy Regulates Cholesterol Efflux from Macrophage Foam Cells via Lysosomal Acid Lipase

(2011) Mireille Ouimet et al.   Cell Metabolism

Pivotal Role for Platelet-Activating Factor Receptor in CD36 Expression and oxLDL Uptake by Human Monocytes/Macrophages

(2011) Francisco J.O. Rios et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Reversal of Hyperlipidemia With a Genetic Switch Favorably Affects the Content and Inflammatory State of Macrophages in Atherosclerotic Plaques

(2011) Jonathan E. Feig et al.   CIRCULATION

Effect of overexpression of human SR-AI on oxLDL uptake and apoptosis in 293T cells

(2011) Hong Yang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Suppressed monocyte recruitment drives macrophage removal from atherosclerotic plaques of Apoe–/– mice during disease regression

(2011) Stephane Potteaux et al.   JOURNAL OF CLINICAL INVESTIGATION

Continued clearance of apoptotic cells critically depends on the phagocyte Ucp2 protein

(2011) Daeho Park et al.   NATURE

Atherosclerosis: current pathogenesis and therapeutic options

(2011) Christian Weber et al.   NATURE MEDICINE

HDL promotes rapid atherosclerosis regression in mice and alters inflammatory properties of plaque monocyte-derived cells

(2011) J. E. Feig et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxidant Production, oxLDL Uptake, and CD36 Levels in Human Monocyte–Derived Macrophages Are Downregulated by the Macrophage-Generated Antioxidant 7,8-Dihydroneopterin

(2010) Steven P. Gieseg et al.   ANTIOXIDANTS & REDOX SIGNALING

Antagonistic regulation of macrophage phenotype by M-CSF and GM-CSF: Implication in atherosclerosis

(2010) Isabelle Brochériou et al.   ATHEROSCLEROSIS

Expression of IL-17A in human atherosclerotic lesions is associated with increased inflammation and plaque vulnerability

(2010) Christian Erbel et al.   BASIC RESEARCH IN CARDIOLOGY

Adipocyte-derived lipids increase angiotensin-converting enzyme (ACE) expression and modulate macrophage phenotype

(2010) Karin Kohlstedt et al.   BASIC RESEARCH IN CARDIOLOGY

Identification of a Novel Macrophage Phenotype That Develops in Response to Atherogenic Phospholipids via Nrf2

(2010) Alexandra Kadl et al.   CIRCULATION RESEARCH

The Role of Endoplasmic Reticulum Stress in the Progression of Atherosclerosis

(2010) Ira Tabas   CIRCULATION RESEARCH

Sphingosine-1-Phosphate Receptor 3 Promotes Recruitment of Monocyte/Macrophages in Inflammation and Atherosclerosis

(2010) Petra Keul et al.   CIRCULATION RESEARCH

Induction of the unfolded protein response after monocyte to macrophage differentiation augments cell survival in early atherosclerotic lesions

(2010) Jeffrey G. Dickhout et al.   FASEB JOURNAL

Acyl-coenzyme A:cholesterol acyltransferases

(2009) Ta-Yuan Chang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Macrophage Diversity and Polarization in Atherosclerosis

(2009) Alberto Mantovani et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Multi-slice computed tomography with N1177 identifies ruptured atherosclerotic plaques in rabbits

(2009) Jozef Leo Herck et al.   BASIC RESEARCH IN CARDIOLOGY

Proteasome inhibitor bortezomib promotes a rupture-prone plaque phenotype in ApoE-deficient mice

(2009) Jozef Leo Herck et al.   BASIC RESEARCH IN CARDIOLOGY

Long-term treatment with the AT1-receptor antagonist telmisartan inhibits biglycan accumulation in murine atherosclerosis

(2009) Nadine Nagy et al.   BASIC RESEARCH IN CARDIOLOGY

Reduced Apoptosis and Plaque Necrosis in Advanced Atherosclerotic Lesions of Apoe−/− and Ldlr−/− Mice Lacking CHOP

(2009) Edward Thorp et al.   Cell Metabolism

Autophagy in Atherosclerosis

(2009) Wim Martinet et al.   CIRCULATION RESEARCH

Macrophage antioxidant protection within atherosclerotic plaques

(2009) Steven et al.   Frontiers in Bioscience-Landmark

Hypoxia Prolongs Monocyte/Macrophage Survival and Enhanced Glycolysis Is Associated with Their Maturation under Aerobic Conditions

(2009) J. Roiniotis et al.   JOURNAL OF IMMUNOLOGY

Mer tyrosine kinase (MerTK) promotes macrophage survival following exposure to oxidative stress

(2009) Adil Anwar et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The Protein Synthesis Inhibitor Anisomycin Induces Macrophage Apoptosis in Rabbit Atherosclerotic Plaques through p38 Mitogen-Activated Protein Kinase

(2009) V. Croons et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Orally delivered siRNA targeting macrophage Map4k4 suppresses systemic inflammation

(2009) Myriam Aouadi et al.   NATURE

Oxidized LDL-Mediated Macrophage Survival Involves Elongation Factor-2 Kinase

(2008) Johnny H. Chen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Brief Report: Increased Apoptosis in Advanced Atherosclerotic Lesions of Apoe −/− Mice Lacking Macrophage Bcl-2

(2008) Edward Thorp et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

CX3CR1 is required for monocyte homeostasis and atherogenesis by promoting cell survival

(2008) L. Landsman et al.   BLOOD

Macrophage EP4 Deficiency Increases Apoptosis and Suppresses Early Atherosclerosis

(2008) Vladimir R. Babaev et al.   Cell Metabolism

MAPK signalling in cardiovascular health and disease: molecular mechanisms and therapeutic targets

(2008) Anthony J. Muslin   CLINICAL SCIENCE

A moderate reduction in extracellular pH protects macrophages against apoptosis induced by oxidized low density lipoprotein

(2008) Andrew B. Gerry et al.   JOURNAL OF LIPID RESEARCH

Hypoxia, Hypoxia-Inducible Transcription Factor, and Macrophages in Human Atherosclerotic Plaques Are Correlated With Intraplaque Angiogenesis

(2008) Judith C. Sluimer et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Macrophages: An elusive yet emerging therapeutic target of atherosclerosis

(2007) R.L. Tiwari et al.   MEDICINAL RESEARCH REVIEWS