KYP-2047 Penetrates Mouse Brain and Effectively Inhibits Mouse Prolyl Oligopeptidase

A Novel Proteolytic Cascade Generates an Extracellular Matrix-Derived Chemoattractant in Chronic Neutrophilic Inflammation

(2014) A. Gaggar et al.   JOURNAL OF IMMUNOLOGY

AcSDKP Regulates Cell Proliferation through the PI3KCA/Akt Signaling Pathway

(2013) Ping Hu et al.   PLoS One

A prolyl oligopeptidase inhibitor, KYP-2047, reduces α-synuclein protein levels and aggregates in cellular and animal models of Parkinson's disease

(2012) TT Myöhänen et al.   BRITISH JOURNAL OF PHARMACOLOGY

Different Interactions of Prolyl Oligopeptidase and Neurotensin in Dopaminergic Function of the Rat Nigrostriatal and Mesolimbic Pathways

(2012) I. Peltonen et al.   NEUROCHEMICAL RESEARCH

Brain Pharmacokinetics of Two Prolyl Oligopeptidase Inhibitors, JTP-4819 and KYP-2047, in the Rat

(2011) Aaro J. Jalkanen et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Interaction of Prolyl Oligopeptidase with α-Synuclein

(2011) Anne-Marie Lambeir   CNS & Neurological Disorders-Drug Targets

The effect of prolyl oligopeptidase inhibition on extracellular acetylcholine and dopamine levels in the rat striatum

(2011) Aaro J. Jalkanen et al.   NEUROCHEMISTRY INTERNATIONAL

Prolyl oligopeptidase induces angiogenesis bothin vitroandin vivoin a novel regulatory manner

(2010) TT Myöhänen et al.   BRITISH JOURNAL OF PHARMACOLOGY

Different Effects of Scopolamine and Inhibition of Prolyl Oligopeptidase on Mnemonic and Motility Functions of Young and 8- to 9-Month-Old Rats in the Radial-Arm Maze

(2009) Iida Peltonen et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Neutrophils contain prolyl endopeptidase and generate the chemotactic peptide, PGP, from collagen

(2009) Philip J. O'Reilly et al.   JOURNAL OF NEUROIMMUNOLOGY

Prolyl oligopeptidase binds to GAP-43 and functions without its peptidase activity

(2009) Elena Di Daniel et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Prolyl oligopeptidase stimulates the aggregation of α-synuclein

(2008) Inger Brandt et al.   PEPTIDES