Gambogic Acid as a Non-Competitive Inhibitor of ATP-Binding Cassette Transporter B1 Reverses the Multidrug Resistance of Human Epithelial Cancers by Promoting ATP-Binding Cassette Transporter B1 Protein Degradation

Mechanisms of Gambogic Acid-Induced Apoptosis in Non-Small Cell Lung Cancer Cells in Relation to Transferrin Receptors

(2014) Xiaoli Zhu et al.   JOURNAL OF CHEMOTHERAPY

Gambogic acid enhances proteasome inhibitor-induced anticancer activity

(2011) Hongbiao Huang et al.   CANCER LETTERS

20(S)-Protopanaxadiol, a metabolite of ginsenosides, induced cell apoptosis through endoplasmic reticulum stress in human hepatocarcinoma HepG2 cells

(2011) Guo-Yuan Zhu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Gambogic Acid, a Natural Product Inhibitor of Hsp90

(2011) Jason Davenport et al.   JOURNAL OF NATURAL PRODUCTS

Putative tumor suppressor miR-145 inhibits colon cancer cell growth by targeting oncogene friend leukemia virus integration 1 gene

(2010) Jianjun Zhang et al.   CANCER

Apatinib (YN968D1) Reverses Multidrug Resistance by Inhibiting the Efflux Function of Multiple ATP-Binding Cassette Transporters

(2010) Y.-j. Mi et al.   CANCER RESEARCH

The Role of Cerebral Vascular NFĸB in LPS-induced Inflammation: Differential Regulation of Efflux Transporter and Transporting Cytokine Receptors

(2010) Weihong Pan et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Chemistry and Biology of the CagedGarciniaXanthones

(2010) Oraphin Chantarasriwong et al.   CHEMISTRY-A EUROPEAN JOURNAL

Interaction of Tyrosine Kinase Inhibitors with the MDR-Related ABC Transporter Proteins

(2010) Xiao-Kun Wang et al.   CURRENT DRUG METABOLISM

Gambogic acid-induced degradation of mutant p53 is mediated by proteasome and related to CHIP

(2010) Jia Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Establishment and characterization of an HPV16 E6/E7-expressing oral squamous cell carcinoma cell line with enhanced tumorigenicity

(2010) Dongxia Ye et al.   MEDICAL ONCOLOGY

The NF-kappa B inhibitor, celastrol, could enhance the anti-cancer effect of gambogic acid on oral squamous cell carcinoma

(2009) Di He et al.   BMC CANCER

Influence of ABCB1 gene polymorphisms on the pharmacokinetics of verapamil among healthy Chinese Han ethnic subjects

(2009) Li-Mei Zhao et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Vascular endothelial growth factor (VEGF) enhances gastric carcinoma invasiveness via integrin alpha(v)beta6

(2009) Rui Zhao et al.   CANCER LETTERS

Reversal of P-glycoprotein-Mediated Multidrug Resistance by the Murine Double Minute 2 Antagonist Nutlin-3

(2009) M. Michaelis et al.   CANCER RESEARCH

Intracellular Trafficking of MDR Transporters and Relevance of SNPs

(2009) Letizia Porcelli et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Chemo-Enzymatic Transformation of Taxanes and their Reversal Activity towards MDR Tumor Cells

(2009) Jungui Dai   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Mechanisms of tumor resistance to EGFR-targeted therapies

(2009) Elizabeth A Hopper-Borge et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Reversal of P-glycoprotein-mediated multi-drug resistance by the E3 ubiquitin ligase Cbl-b in human gastric adenocarcinoma cells

(2009) Ye Zhang et al.   JOURNAL OF PATHOLOGY

ABC Transporters as Potential Targets for Modulation of Drug Resistance

(2009) L. Gatti et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Enhancement of Doxorubicin Cytotoxicity on Human Esophageal Squamous Cell Carcinoma Cells by Indomethacin and 4-[5-(4-Chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide (SC236) via Inhibiting P-Glycoprotein Activity

(2009) L. Yu et al.   MOLECULAR PHARMACOLOGY

ABC transporters: the power to change

(2009) Douglas C. Rees et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Inhibition of anticancer drug efflux transporter P-glycoprotein by rosemary phytochemicals

(2009) Tomohiro Nabekura et al.   PHARMACOLOGICAL RESEARCH

NSC23925, Identified in a High-Throughput Cell-Based Screen, Reverses Multidrug Resistance

(2009) Zhenfeng Duan et al.   PLoS One

Gambogic Acid Inhibits Angiogenesis and Prostate Tumor Growth by Suppressing Vascular Endothelial Growth Factor Receptor 2 Signaling

(2008) T. Yi et al.   CANCER RESEARCH

Hyaluronan-mediated CD44 Interaction with p300 and SIRT1 Regulates β-Catenin Signaling and NFκB-specific Transcription Activity Leading to MDR1 and Bcl-xLGene Expression and Chemoresistance in Breast Tumor Cells

(2008) Lilly Y. W. Bourguignon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gambogic acid is an antagonist of antiapoptotic Bcl-2 family proteins

(2008) Dayong Zhai et al.   MOLECULAR CANCER THERAPEUTICS

Synergistic effect of 5-fluorouracil with gambogic acid on BGC-823 human gastric carcinoma

(2008) Jun Wang et al.   TOXICOLOGY