Selective autophagy against membranous compartments

Noncanonical Autophagy Promotes the Visual Cycle

(2013) Ji-Young Kim et al.   CELL

Up-to-date membrane biogenesis in the autophagosome formation

(2013) Maho Hamasaki et al.   CURRENT OPINION IN CELL BIOLOGY

TMEM59 defines a novel ATG16L1-binding motif that promotes local activation of LC3

(2013) Emilio Boada-Romero et al.   EMBO JOURNAL

Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury

(2013) Ikuko Maejima et al.   EMBO JOURNAL

Non-autophagic roles of autophagy-related proteins

(2013) Suresh Subramani et al.   EMBO REPORTS

Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization

(2013) Shireen A. Sarraf et al.   NATURE

Autophagosomes form at ER–mitochondria contact sites

(2013) Maho Hamasaki et al.   NATURE

Autophagy in Human Health and Disease

(2013) Augustine M.K. Choi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Nondegradative Role of Atg5-Atg12/ Atg16L1 Autophagy Protein Complex in Antiviral Activity of Interferon Gamma

(2012) Seungmin Hwang et al.   Cell Host & Microbe

Selective Subversion of Autophagy Complexes Facilitates Completion of the Brucella Intracellular Cycle

(2012) Tregei Starr et al.   Cell Host & Microbe

Mechanisms of Autophagosome Biogenesis

(2012) David C. Rubinsztein et al.   CURRENT BIOLOGY

Noncanonical Autophagy Is Required for Type I Interferon Secretion in Response to DNA-Immune Complexes

(2012) Jill Henault et al.   IMMUNITY

Atg16L1, an essential factor for canonical autophagy, participates in hormone secretion from PC12 cells independently of autophagic activity

(2012) Koutaro Ishibashi et al.   MOLECULAR BIOLOGY OF THE CELL

LC3C, Bound Selectively by a Noncanonical LIR Motif in NDP52, Is Required for Antibacterial Autophagy

(2012) Natalia von Muhlinen et al.   MOLECULAR CELL

Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion

(2012) Teresa L. M. Thurston et al.   NATURE

Autophagy modulation as a potential therapeutic target for diverse diseases

(2012) David C. Rubinsztein et al.   NATURE REVIEWS DRUG DISCOVERY

Autophagy intersections with conventional and unconventional secretion in tissue development, remodeling and inflammation

(2012) Vojo Deretic et al.   TRENDS IN CELL BIOLOGY

Autophagy proteins in macroendocytic engulfment

(2012) Oliver Florey et al.   TRENDS IN CELL BIOLOGY

The Role of Atg Proteins in Autophagosome Formation

(2011) Noboru Mizushima et al.   Annual Review of Cell and Developmental Biology

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

Autophagy in the Cellular Energetic Balance

(2011) Rajat Singh et al.   Cell Metabolism

Autophagy Proteins Regulate the Secretory Component of Osteoclastic Bone Resorption

(2011) Carl J. DeSelm et al.   DEVELOPMENTAL CELL

Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β

(2011) Nicolas Dupont et al.   EMBO JOURNAL

Autophagy in immunity and cell-autonomous defense against intracellular microbes

(2011) Vojo Deretic   IMMUNOLOGICAL REVIEWS

The LC3 recruitment mechanism is separate from Atg9L1-dependent membrane formation in the autophagic response against Salmonella

(2011) Shun Kageyama et al.   MOLECULAR BIOLOGY OF THE CELL

Autophagy machinery mediates macroendocytic processing and entotic cell death by targeting single membranes

(2011) Oliver Florey et al.   NATURE CELL BIOLOGY

Control of autophagy as a therapy for neurodegenerative disease

(2011) Harry Harris et al.   Nature Reviews Neurology

The Burkholderia pseudomallei Type III Secretion System and BopA Are Required for Evasion of LC3-Associated Phagocytosis

(2011) Lan Gong et al.   PLoS One

Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells

(2011) J. Martinez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of the Autophagy Receptor Optineurin Restricts Salmonella Growth

(2011) P. Wild et al.   SCIENCE

Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins

(2010) Eisuke Itakura et al.   Autophagy

Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation

(2010) Hannah E.J. Polson et al.   Autophagy

Virus-Plus-Susceptibility Gene Interaction Determines Crohn's Disease Gene Atg16L1 Phenotypes in Intestine

(2010) Ken Cadwell et al.   CELL

Mitochondria Supply Membranes for Autophagosome Biogenesis during Starvation

(2010) Dale W. Hailey et al.   CELL

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

Coronaviruses Hijack the LC3-I-Positive EDEMosomes, ER-Derived Vesicles Exporting Short-Lived ERAD Regulators, for Replication

(2010) Fulvio Reggiori et al.   Cell Host & Microbe

Autophagosomes can support Yersinia pseudotuberculosis replication in macrophages

(2010) Kevin Moreau et al.   CELLULAR MICROBIOLOGY

Role of autophagy in suppression of inflammation and cancer

(2010) Eileen White et al.   CURRENT OPINION IN CELL BIOLOGY

Mechanisms and consequences of bacterial targeting by the autophagy pathway

(2010) Shahab Shahnazari et al.   CURRENT OPINION IN MICROBIOLOGY

LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis

(2010) Hilla Weidberg et al.   EMBO JOURNAL

Atg8-family interacting motif crucial for selective autophagy

(2010) Nobuo N. Noda et al.   FEBS LETTERS

MBSJ MCC Young Scientist Award 2009
REVIEW: Selective autophagy regulates various cellular functions

(2010) Masaaki Komatsu et al.   GENES TO CELLS

In Vivo Requirement for Atg5 in Antigen Presentation by Dendritic Cells

(2010) Heung Kyu Lee et al.   IMMUNITY

Unconventional secretion of Acb1 is mediated by autophagosomes

(2010) Juan M. Duran et al.   JOURNAL OF CELL BIOLOGY

Unconventional secretion ofPichia pastorisAcb1 is dependent on GRASP protein, peroxisomal functions, and autophagosome formation

(2010) Ravi Manjithaya et al.   JOURNAL OF CELL BIOLOGY

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

(2010) Noriyuki Matsuda et al.   JOURNAL OF CELL BIOLOGY

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Autophagy in mammalian development and differentiation

(2010) Noboru Mizushima et al.   NATURE CELL BIOLOGY

Plasma membrane contributes to the formation of pre-autophagosomal structures

(2010) Brinda Ravikumar et al.   NATURE CELL BIOLOGY

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

(2010) Sven Geisler et al.   NATURE CELL BIOLOGY

Autophagy and Metabolism

(2010) J. D. Rabinowitz et al.   SCIENCE

Regulation of macroautophagy in Saccharomyces cerevisiae

(2010) Yuko Inoue et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

(2010) Derek P. Narendra et al.   PLOS BIOLOGY

Autophagy Suppresses Tumorigenesis through Elimination of p62

(2009) Robin Mathew et al.   CELL

The late stages of autophagy: how does the end begin?

(2009) T Noda et al.   CELL DEATH AND DIFFERENTIATION

Coxiella burnetii modulates Beclin 1 and Bcl-2, preventing host cell apoptosis to generate a persistent bacterial infection

(2009) C L Vázquez et al.   CELL DEATH AND DIFFERENTIATION

Autophagy, Immunity, and Microbial Adaptations

(2009) Vojo Deretic et al.   Cell Host & Microbe

Mammalian autophagy: core molecular machinery and signaling regulation

(2009) Zhifen Yang et al.   CURRENT OPINION IN CELL BIOLOGY

Nix is a selective autophagy receptor for mitochondrial clearance

(2009) Ivana Novak et al.   EMBO REPORTS

Yersinia pestis Can Reside in Autophagosomes and Avoid Xenophagy in Murine Macrophages by Preventing Vacuole Acidification

(2009) C. Pujol et al.   INFECTION AND IMMUNITY

Differential Involvement of Atg16L1 in Crohn Disease and Canonical Autophagy

(2009) Naonobu Fujita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Role for Ubiquitin in Selective Autophagy

(2009) Vladimir Kirkin et al.   MOLECULAR CELL

A Role for NBR1 in Autophagosomal Degradation of Ubiquitinated Substrates

(2009) Vladimir Kirkin et al.   MOLECULAR CELL

A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation

(2009) Mitsuko Hayashi-Nishino et al.   NATURE CELL BIOLOGY

Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

(2009) Leonardo H Travassos et al.   NATURE IMMUNOLOGY

The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria

(2009) Teresa L M Thurston et al.   NATURE IMMUNOLOGY

Dynamics and diversity in autophagy mechanisms: lessons from yeast

(2009) Hitoshi Nakatogawa et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Activation of antibacterial autophagy by NADPH oxidases

(2009) J. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

(2009) C. Vives-Bauza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

The Role of Autophagy in Mammalian Development: Cell Makeover Rather than Cell Death

(2008) Francesco Cecconi et al.   DEVELOPMENTAL CELL

Toll-like receptors control autophagy

(2008) Mónica A Delgado et al.   EMBO JOURNAL

Toll-like receptor signaling in the lysosomal pathways

(2008) Miguel A. Sanjuan et al.   IMMUNOLOGICAL REVIEWS

Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum

(2008) Elizabeth L. Axe et al.   JOURNAL OF CELL BIOLOGY

The Atg8 Conjugation System Is Indispensable for Proper Development of Autophagic Isolation Membranes in Mice

(2008) Yu-shin Sou et al.   MOLECULAR BIOLOGY OF THE CELL

An Atg4B Mutant Hampers the Lipidation of LC3 Paralogues and Causes Defects in Autophagosome Closure

(2008) Naonobu Fujita et al.   MOLECULAR BIOLOGY OF THE CELL

The Atg16L Complex Specifies the Site of LC3 Lipidation for Membrane Biogenesis in Autophagy

(2008) Naonobu Fujita et al.   MOLECULAR BIOLOGY OF THE CELL

Listeriolysin O allows Listeria monocytogenes replication in macrophage vacuoles

(2008) Cheryl L. Birmingham et al.   NATURE

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

(2008) Ken Cadwell et al.   NATURE

Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production

(2008) Tatsuya Saitoh et al.   NATURE

Impaired Autophagy of an Intracellular Pathogen Induced by a Crohn's Disease Associated ATG16L1 Variant

(2008) Petric Kuballa et al.   PLoS One

Membrane proteomics of phagosomes suggests a connection to autophagy

(2008) W. Shui et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-Wide siRNA-Based Functional Genomics of Pigmentation Identifies Novel Genes and Pathways That Impact Melanogenesis in Human Cells

(2008) Anand K. Ganesan et al.   PLoS Genetics