New role for EMD (emerin), a key inner nuclear membrane protein, as an enhancer of autophagosome formation in the C16-ceramide autophagy pathway

Regulation of autophagy by ceramide-CD95-PERK signaling

(2014) Margaret A. Park et al.   Autophagy

Autophagic degradation of nuclear components in mammalian cells

(2014) Young-Eun Park et al.   Autophagy

Regulation of Autophagy by Sphingolipids

(2012) Carmen Bedia et al.   Anti-Cancer Agents in Medicinal Chemistry

Ceramide and Apoptosis: Exploring the Enigmatic Connections between Sphingolipid Metabolism and Programmed Cell Death

(2012) Thomas D. Mullen et al.   Anti-Cancer Agents in Medicinal Chemistry

Tumor Cell Autophagy as an Adaptive Response Mediating Resistance to Treatments Such as Antiangiogenic Therapy

(2012) Y.-L. Hu et al.   CANCER RESEARCH

Role of autophagy in diabetes and endoplasmic reticulum stress of pancreatic β-cells

(2012) Wenying Quan et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

The Nuclear Envelope Protein Emerin Binds Directly to Histone Deacetylase 3 (HDAC3) and Activates HDAC3 Activity

(2012) Justin Demmerle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sumoylated protein tyrosine phosphatase 1B localizes to the inner nuclear membrane and regulates the tyrosine phosphorylation of emerin

(2012) S.-C. Yip et al.   JOURNAL OF CELL SCIENCE

Autophagy and ionizing radiation in tumors: The “survive or not survive” dilemma

(2012) Silvia Palumbo et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy

(2012) R David Sentelle et al.   Nature Chemical Biology

Autophagy and disease: always two sides to a problem

(2011) Sunandini Sridhar et al.   JOURNAL OF PATHOLOGY

Targeting autophagy during cancer therapy to improve clinical outcomes

(2011) Jean M. Mulcahy Levy et al.   PHARMACOLOGY & THERAPEUTICS

Beclin 1 over- and underexpression in colorectal cancer: distinct patterns relate to prognosis and tumour hypoxia

(2010) M I Koukourakis et al.   BRITISH JOURNAL OF CANCER

PERK-Dependent Regulation of Ceramide Synthase 6 and Thioredoxin Play a Key Role in mda-7/IL-24-Induced Killing of Primary Human Glioblastoma Multiforme Cells

(2010) A. Yacoub et al.   CANCER RESEARCH

Mechanism of Autophagy to Apoptosis Switch Triggered in Prostate Cancer Cells by Antitumor Cytokine Melanoma Differentiation-Associated Gene 7/Interleukin-24

(2010) Sujit K. Bhutia et al.   CANCER RESEARCH

Ceramide-induced autophagy: To junk or to protect cells?

(2009) Sophie Pattingre et al.   Autophagy

Disruption of ceramide synthesis by CerS2 down-regulation leads to autophagy and the unfolded protein response

(2009) Stefka D. Spassieva et al.   BIOCHEMICAL JOURNAL

Transcriptional regulation of neutral sphingomyelinase 2 gene expression of a human breast cancer cell line, MCF-7, induced by the anti-cancer drug, daunorubicin

(2009) Hiromi Ito et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Tyrosine phosphorylation of nuclear-membrane protein emerin by Src, Abl and other kinases

(2009) K. E. Tifft et al.   JOURNAL OF CELL SCIENCE

The Proapoptotic C16-ceramide-Dependent Pathway Requires the Death-Promoting Factor Btf in Colon Adenocarcinoma Cells

(2009) Anne-Françoise Rénert et al.   JOURNAL OF PROTEOME RESEARCH

Inhibition of mTOR pathway by everolimus cooperates with EGFR inhibitors in human tumours sensitive and resistant to anti-EGFR drugs

(2008) R Bianco et al.   BRITISH JOURNAL OF CANCER

Role of JNK1-dependent Bcl-2 Phosphorylation in Ceramide-induced Macroautophagy

(2008) Sophie Pattingre et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Kinase-Selective Enrichment Enables Quantitative Phosphoproteomics of the Kinome across the Cell Cycle

(2008) Henrik Daub et al.   MOLECULAR CELL

Ceramide starves cells to death by downregulating nutrient transporter proteins

(2008) G. G. Guenther et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantitative phosphoproteome analysis of a mouse liver cell line reveals specificity of phosphatase inhibitors

(2008) Cuiping Pan et al.   PROTEOMICS