Development of Multiple Cell-Based Assays for the Detection of Histone H3 Lys27 Trimethylation (H3K27me3)

Assay Development for Histone Methyltransferases

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EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations

(2012) Michael T. McCabe et al.   NATURE

A Sensitive, Homogeneous, and High-Throughput Assay for Lysine-Specific Histone Demethylases at the H3K4 Site

(2011) Chunhua Wang et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Histone H3 Lysine 79 Methyltransferase Dot1 Is Required for Immortalization by MLL Oncogenes

(2010) M.-J. Chang et al.   CANCER RESEARCH

A chemiluminescence-based method for identification of histone lysine methyltransferase inhibitors

(2010) Amy M. Quinn et al.   Molecular BioSystems

Charting histone modifications and the functional organization of mammalian genomes

(2010) Vicky W. Zhou et al.   NATURE REVIEWS GENETICS

Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas

(2010) C. J. Sneeringer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting epigenetic modifiers: Inhibitors of histone methyltransferases

(2010) Elisabeth-Maria Bissinger et al.   MedChemComm

DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation

(2009) T. B. Miranda et al.   MOLECULAR CANCER THERAPEUTICS

A homogeneous method for investigation of methylation-dependent protein-protein interactions in epigenetics

(2009) A. M. Quinn et al.   NUCLEIC ACIDS RESEARCH