Improved antibiotic production and silent gene activation in Streptomyces diastatochromogenes by ribosome engineering

Overexpression of ribosome recycling factor is responsible for improvement of nucleotide antibiotic-toyocamycin in Streptomyces diastatochromogenes 1628

(2014) Zheng Ma et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Development of Intergeneric Conjugal Gene Transfer System in Streptomyces diastatochromogenes 1628 and Its Application for Improvement of Toyocamycin Production

(2013) Zheng Ma et al.   CURRENT MICROBIOLOGY

Activation and Products of the Cryptic Secondary Metabolite Biosynthetic Gene Clusters by Rifampin Resistance (rpoB) Mutations in Actinomycetes

(2013) Y. Tanaka et al.   JOURNAL OF BACTERIOLOGY

Activating the expression of bacterial cryptic genes by rpoB mutations in RNA polymerase or by rare earth elements

(2013) Kozo Ochi et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Genome shuffling of Streptomyces viridochromogenes for improved production of avilamycin

(2012) Xing-An Lv et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

New strategies for drug discovery: activation of silent or weakly expressed microbial gene clusters

(2012) Kozo Ochi et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Deciphering Deazapurine Biosynthesis: Pathway for Pyrrolopyrimidine Nucleosides Toyocamycin and Sangivamycin

(2008) Reid M. McCarty et al.   CHEMISTRY & BIOLOGY