Diabetes Mellitus and Ischemic Diseases

Role of PFKFB3-Driven Glycolysis in Vessel Sprouting

(2013) Katrien De Bock et al.   CELL

Hyperglycemia Promotes Myelopoiesis and Impairs the Resolution of Atherosclerosis

(2013) Prabhakara R. Nagareddy et al.   Cell Metabolism

Partial and Transient Reduction of Glycolysis by PFKFB3 Blockade Reduces Pathological Angiogenesis

(2013) Sandra Schoors et al.   Cell Metabolism

Desert Hedgehog Promotes Ischemia-Induced Angiogenesis by Ensuring Peripheral Nerve Survival

(2013) Marie-Ange Renault et al.   CIRCULATION RESEARCH

PKCδ Impaired Vessel Formation and Angiogenic Factor Expression in Diabetic Ischemic Limbs

(2013) Farah Lizotte et al.   DIABETES

Nox2 NADPH Oxidase Has a Critical Role in Insulin Resistance-Related Endothelial Cell Dysfunction

(2013) P. Sukumar et al.   DIABETES

Nitrite Anion Therapy Protects Against Chronic Ischemic Tissue Injury in db/db Diabetic Mice in a NO/VEGF-Dependent Manner

(2013) S. C. Bir et al.   DIABETES

Diabetes Causes Bone Marrow Autonomic Neuropathy and Impairs Stem Cell Mobilization via Dysregulated p66Shc and Sirt1

(2013) M. Albiero et al.   DIABETES

Cellular and molecular mechanisms of endothelial dysfunction in diabetes

(2013) Anna C Roberts et al.   Diabetes & Vascular Disease Research

An unbalanced monocyte polarisation in peripheral blood and bone marrow of patients with type 2 diabetes has an impact on microangiopathy

(2013) G. P. Fadini et al.   DIABETOLOGIA

Diabetes Mellitus-Associated Vascular Impairment

(2013) Dimitris Tousoulis et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Divergent angiocrine signals from vascular niche balance liver regeneration and fibrosis

(2013) Bi-Sen Ding et al.   NATURE

Postischemic Revascularization: From Cellular and Molecular Mechanisms to Clinical Applications

(2013) Jean-Sébastien Silvestre et al.   PHYSIOLOGICAL REVIEWS

N-3 Polyunsaturated Fatty Acids Prevent Diabetic Retinopathy by Inhibition of Retinal Vascular Damage and Enhanced Endothelial Progenitor Cell Reparative Function

(2013) Maria Tikhonenko et al.   PLoS One

Secretoneurin Gene Therapy Improves Blood Flow in an Ischemia Model in Type 1 Diabetic Mice by Enhancing Therapeutic Neovascularization

(2013) Wilfried Schgoer et al.   PLoS One

HIF-Prolyl Hydroxylase 2 Inhibition Enhances the Efficiency of Mesenchymal Stem Cell-Based Therapies for the Treatment of Critical Limb Ischemia

(2013) Kiave-Yune HoWangYin et al.   STEM CELLS

Sympathetic Nervous System Regulates Bone Marrow–Derived Cell Egress Through Endothelial Nitric Oxide Synthase Activation

(2012) Alice Récalde et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Dipeptidyl Peptidase-4 Modulates Left Ventricular Dysfunction in Chronic Heart Failure via Angiogenesis-Dependent and -Independent Actions

(2012) Toshimasa Shigeta et al.   CIRCULATION

C/EBP Homologous Protein-10 (CHOP-10) Limits Postnatal Neovascularization Through Control of Endothelial Nitric Oxide Synthase Gene Expression

(2012) Céline Loinard et al.   CIRCULATION

Global Remodeling of the Vascular Stem Cell Niche in Bone Marrow of Diabetic Patients

(2012) Gaia Spinetti et al.   CIRCULATION RESEARCH

MicroRNA-15a and MicroRNA-16 Impair Human Circulating Proangiogenic Cell Functions and Are Increased in the Proangiogenic Cells and Serum of Patients With Critical Limb Ischemia

(2012) Gaia Spinetti et al.   CIRCULATION RESEARCH

Ephrin-B2-Activated Peripheral Blood Mononuclear Cells From Diabetic Patients Restore Diabetes-Induced Impairment of Postischemic Neovascularization

(2012) D. Broqueres-You et al.   DIABETES

Long-term type 1 diabetes influences haematopoietic stem cells by reducing vascular repair potential and increasing inflammatory monocyte generation in a murine model

(2012) S. Hazra et al.   DIABETOLOGIA

Targeting VEGF-B as a novel treatment for insulin resistance and type 2 diabetes

(2012) Carolina E. Hagberg et al.   NATURE

Overexpression of Angiopoietin-1 Increases CD133+/c-kit+ Cells and Reduces Myocardial Apoptosis in db/db Mouse Infarcted Hearts

(2012) Heng Zeng et al.   PLoS One

Endothelial Nitric Oxide Synthase Overexpression Restores the Efficiency of Bone Marrow Mononuclear Cell-Based Therapy

(2011) Barend Mees et al.   AMERICAN JOURNAL OF PATHOLOGY

Overexpression of angiopoietin-2 impairs myocardial angiogenesis and exacerbates cardiac fibrosis in the diabetic db/db mouse model

(2011) Jian-Xiong Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Dysregulated Selectin Expression and Monocyte Recruitment During Ischemia-Related Vascular Remodeling in Diabetes Mellitus

(2011) Chad L. Carr et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Nox2-derived reactive oxygen species contribute to hypercholesterolemia-induced inhibition of neovascularization: Effects on endothelial progenitor cells and mature endothelial cells

(2011) Paola Haddad et al.   ATHEROSCLEROSIS

Deregulation of microRNA-503 Contributes to Diabetes Mellitus–Induced Impairment of Endothelial Function and Reparative Angiogenesis After Limb Ischemia

(2011) Andrea Caporali et al.   CIRCULATION

The Unconventional Role of Acid Sphingomyelinase in Regulation of Retinal Microangiopathy in Diabetic Human and Animal Models

(2011) M. Opreanu et al.   DIABETES

Regulation of hypoxia-inducible factor 1 and the loss of the cellular response to hypoxia in diabetes

(2011) C. F. Bento et al.   DIABETOLOGIA

The endothelin receptor antagonist bosentan improves peripheral endothelial function in patients with type 2 diabetes mellitus and microalbuminuria: a randomised trial

(2011) A. Rafnsson et al.   DIABETOLOGIA

Regulation of Bone Marrow-Derived Vascular Progenitor Cell Mobilization and Maintenance

(2010) Stefanie Dimmeler   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Increase in GLUT1 in Smooth Muscle Alters Vascular Contractility and Increases Inflammation in Response to Vascular Injury

(2010) Neeta Adhikari et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Regulation of monocyte subset systemic levels by distinct chemokine receptors controls post-ischaemic neovascularization

(2010) C. Cochain et al.   CARDIOVASCULAR RESEARCH

Thioredoxin-1 Gene Therapy Enhances Angiogenic Signaling and Reduces Ventricular Remodeling in Infarcted Myocardium of Diabetic Rats

(2010) Samson Mathews Samuel et al.   CIRCULATION

Tissue Kallikrein Is Essential for Invasive Capacity of Circulating Proangiogenic Cells

(2010) Gaia Spinetti et al.   CIRCULATION RESEARCH

Vascular endothelial growth factor B controls endothelial fatty acid uptake

(2010) Carolina E. Hagberg et al.   NATURE

Inhibition of Prolyl Hydroxylase Domain Proteins Promotes Therapeutic Revascularization

(2009) Céline Loinard et al.   CIRCULATION

Inhibition of Semaphorin As a Novel Strategy for Therapeutic Angiogenesis

(2009) Junji Moriya et al.   CIRCULATION RESEARCH

Coadministration of Adenoviral Vascular Endothelial Growth Factor and Angiopoietin-1 Enhances Vascularization and Reduces Ventricular Remodeling in the Infarcted Myocardium of Type 1 Diabetic Rats

(2009) S. M. Samuel et al.   DIABETES

Diabetic retinopathy is associated with bone marrow neuropathy and a depressed peripheral clock

(2009) Julia V. Busik et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The molecular basis for impaired hypoxia-induced VEGF expression in diabetic tissues

(2009) H. Thangarajah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adenoviral transfer of HIF-1  enhances vascular responses to critical limb ischemia in diabetic mice

(2009) K. Sarkar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disruption of Ang-1/Tie-2 Signaling Contributes to the Impaired Myocardial Vascular Maturation and Angiogenesis in Type II Diabetic Mice

(2008) Jian-Xiong Chen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

MicroRNA-320 EXPRESSION IN MYOCARDIAL MICROVASCULAR ENDOTHELIAL CELLS AND ITS RELATIONSHIP WITH INSULIN-LIKE GROWTH FACTOR-1 IN TYPE 2 DIABETIC RATS

(2008) XH Wang et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Ang-1 Gene Therapy Inhibits Hypoxia-Inducible Factor-1  (HIF-1 )-Prolyl-4-Hydroxylase-2, Stabilizes HIF-1  Expression, and Normalizes Immature Vasculature in db/db Mice

(2008) J.-X. Chen et al.   DIABETES

Impaired Collateral Recruitment and Outward Remodeling in Experimental Diabetes

(2008) J. M. van Golde et al.   DIABETES

AT1-receptor blockade by telmisartan upregulates GTP-cyclohydrolase I and protects eNOS in diabetic rats

(2008) Philip Wenzel et al.   FREE RADICAL BIOLOGY AND MEDICINE

Stabilization of HIF-1  is critical to improve wound healing in diabetic mice

(2008) I. R. Botusan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA