Production of chlorzoxazone glucuronides via cytochrome P4502E1 dependent and independent pathways in human hepatocytes

Higher chlorzoxazone clearance in obese children compared with nonobese peers

(2018) C. Gade et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

A cocktail approach for assessing the in vitro activity of human cytochrome P450s: An overview of current methodologies

(2014) Dany Spaggiari et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Methodology to assay CYP2E1 mixed function oxidase catalytic activity and its induction

(2014) Arthur I. Cederbaum   Redox Biology

The UDP-glucuronosyltransferases: Their role in drug metabolism and detoxification

(2013) Andrew Rowland et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation

(2013) Ulrich M. Zanger et al.   PHARMACOLOGY & THERAPEUTICS

Increased susceptibility of natural killer T-cell-deficient mice to acetaminophen-induced liver injury

(2012) Brittany V. Martin-Murphy et al.   HEPATOLOGY

Critical role of cytochrome P450 2E1 (CYP2E1) in the development of high fat-induced non-alcoholic steatohepatitis

(2012) Mohamed A. Abdelmegeed et al.   JOURNAL OF HEPATOLOGY

Three-Dimensional HepaRG Model As An Attractive Tool for Toxicity Testing

(2012) Sofia B. Leite et al.   TOXICOLOGICAL SCIENCES

Increased expression of cytochrome P450 2E1 in nonalcoholic fatty liver disease: Mechanisms and pathophysiological role

(2011) J. Aubert et al.   Clinics and Research in Hepatology and Gastroenterology

Preferential induction of the AhR gene battery in HepaRG cells after a single or repeated exposure to heterocyclic aromatic amines

(2010) Julie Dumont et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Evaluation of HepaRG Cells as an in Vitro Model for Human Drug Metabolism Studies

(2008) K. P. Kanebratt et al.   DRUG METABOLISM AND DISPOSITION