Mitochondrial dysregulation and protection in cisplatin nephrotoxicity

Mitochondrial form and function

(2014) Jonathan R. Friedman et al.   NATURE

Mitochondria-mediated mitigatory role of curcumin in cisplatin-induced nephrotoxicity

(2013) Mohammad Waseem et al.   CELL BIOCHEMISTRY AND FUNCTION

Bax and Bak have critical roles in ischemic acute kidney injury in global and proximal tubule–specific knockout mouse models

(2013) Qingqing Wei et al.   KIDNEY INTERNATIONAL

Mitochondrial dynamics: regulatory mechanisms and emerging role in renal pathophysiology

(2013) Ming Zhan et al.   KIDNEY INTERNATIONAL

Autophagy in Acute Kidney Injury

(2013) Man J. Livingston et al.   SEMINARS IN NEPHROLOGY

Autophagy Guards Against Cisplatin-Induced Acute Kidney Injury

(2012) Atsushi Takahashi et al.   AMERICAN JOURNAL OF PATHOLOGY

Autophagy in proximal tubules protects against acute kidney injury

(2012) Man Jiang et al.   KIDNEY INTERNATIONAL

Mitochondrial Fission, Fusion, and Stress

(2012) R. J. Youle et al.   SCIENCE

Fusion and Fission: Interlinked Processes Critical for Mitochondrial Health

(2011) David C. Chan   Annual Review of Genetics

Mitochondrial-targeted antioxidants represent a promising approach for prevention of cisplatin-induced nephropathy

(2011) Partha Mukhopadhyay et al.   FREE RADICAL BIOLOGY AND MEDICINE

hMSH2 Recruits ATR to DNA Damage Sites for Activation during DNA Damage-induced Apoptosis

(2011) Navjotsingh Pabla et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of PKCδ reduces cisplatin-induced nephrotoxicity without blocking chemotherapeutic efficacy in mouse models of cancer

(2011) Navjotsingh Pabla et al.   JOURNAL OF CLINICAL INVESTIGATION

Fragmented mitochondria are sensitized to Bax insertion and activation during apoptosis

(2010) Craig Brooks et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Carvedilol protects against cisplatin-induced oxidative stress, redox state unbalance and apoptosis in rat kidney mitochondria

(2010) M.A. Carvalho Rodrigues et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Dasatinib Plus Nutlin-3 Shows Synergistic Antileukemic Activity in Both p53wild-type and p53mutated B Chronic Lymphocytic Leukemias by Inhibiting the Akt Pathway

(2010) G. Zauli et al.   CLINICAL CANCER RESEARCH

Chemically modified non-antimicrobial tetracyclines are multifunctional drugs against advanced cancers☆

(2010) Bal L. Lokeshwar   PHARMACOLOGICAL RESEARCH

Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models

(2009) Craig Brooks et al.   JOURNAL OF CLINICAL INVESTIGATION

Alpha-Lipoic Acid Attenuates Cisplatin-Induced Tubulointerstitial Injuries through Inhibition of Mitochondrial Bax Translocation in Rats

(2009) Young Mo Lee et al.   NEPHRON EXPERIMENTAL NEPHROLOGY

Regulation and Pathological Role of p53 in Cisplatin Nephrotoxicity

(2008) M. Jiang et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Autophagy is cytoprotective during cisplatin injury of renal proximal tubular cells

(2008) Sudharsan Periyasamy-Thandavan et al.   KIDNEY INTERNATIONAL

Cisplatin nephrotoxicity: Mechanisms and renoprotective strategies

(2008) N. Pabla et al.   KIDNEY INTERNATIONAL