Genotoxic and carcinogenic potential of engineered nanoparticles: an update

Zinc oxide nanoparticles induce oxidative DNA damage and ROS-triggered mitochondria mediated apoptosis in human liver cells (HepG2)

(2012) Vyom Sharma et al.   APOPTOSIS

Toxico-/biokinetics of nanomaterials

(2012) Robert Landsiedel et al.   ARCHIVES OF TOXICOLOGY

Oxidative stress in apoptosis and cancer: an update

(2012) José M. Matés et al.   ARCHIVES OF TOXICOLOGY

The induction of angiogenesis by cerium oxide nanoparticles through the modulation of oxygen in intracellular environments

(2012) Soumen Das et al.   BIOMATERIALS

Oxidative stress and metal carcinogenesis

(2012) Jeong-Chae Lee et al.   FREE RADICAL BIOLOGY AND MEDICINE

Silver nanoparticles induce premutagenic DNA oxidation that can be prevented by phytochemicals from Gentiana asclepiadea

(2012) A. Hudecova et al.   MUTAGENESIS

DNA damage induced by micro- and nanoparticles--interaction with FPG influences the detection of DNA oxidation in the comet assay

(2012) J. Kain et al.   MUTAGENESIS

Nanomaterials: Exposure, Effects and Toxicity Assessment

(2012) Vyom Sharma et al.   Proceedings of the National Academy of Sciences, India. Section B

Toxicology of nanoparticles

(2011) Andreas Elsaesser et al.   ADVANCED DRUG DELIVERY REVIEWS

Evaluation of the cytotoxic and inflammatory potential of differentially shaped zinc oxide nanoparticles

(2011) Boon Chin Heng et al.   ARCHIVES OF TOXICOLOGY

Induction of ROS, mitochondrial damage and autophagy in lung epithelial cancer cells by iron oxide nanoparticles

(2011) Mohd Imran Khan et al.   BIOMATERIALS

Cytotoxicity and Genotoxicity of Size-Fractionated Iron Oxide (Magnetite) in A549 Human Lung Epithelial Cells: Role of ROS, JNK, and NF-κB

(2011) Mathias Könczöl et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Genotoxicity Evaluation of Nanomaterials: DNA Damage, Micronuclei, and 8-Hydroxy-2-deoxyguanosine Induced by Magnetic Doped CdSe Quantum Dots in Male Mice

(2011) W. K. B. Khalil et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Cellular uptake and mutagenic potential of metal oxide nanoparticles in bacterial cells

(2011) Ashutosh Kumar et al.   CHEMOSPHERE

Chronic exposure to nanosized, anatase titanium dioxide is not cyto- or genotoxic to Chinese hamster ovary cells

(2011) Shuguang Wang et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Repetitive exposure to zinc oxide nanoparticles induces dna damage in human nasal mucosa mini organ cultures

(2011) Stephan Hackenberg et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Engineered ZnO and TiO2 nanoparticles induce oxidative stress and DNA damage leading to reduced viability of Escherichia coli

(2011) Ashutosh Kumar et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cellular Response to Metal Oxide Nanoparticles in Bacteria

(2011) Ashutosh Kumar et al.   Journal of Biomedical Nanotechnology

The Need for Novel Approaches in Ecotoxicity of Engineered Nanomaterials

(2011) Ashutosh Kumar et al.   Journal of Biomedical Nanotechnology

Interaction of C60 Fullerene with the Proteins Involved in DNA Mismatch Repair Pathway

(2011) Shishir Kumar Gupta et al.   Journal of Biomedical Nanotechnology

Titanium Dioxide Nanoparticles Induce Oxidative Stress-Mediated Apoptosis in Human Keratinocyte Cells

(2011) RiteshK. Shukla et al.   Journal of Biomedical Nanotechnology

C60-Fullerene Binds with the ATP Binding Domain of Human DNA Topoiosmerase II Alpha

(2011) Lokesh Baweja et al.   Journal of Biomedical Nanotechnology

Toxicity of Graphene in Normal Human Lung Cells (BEAS-2B)

(2011) N. V. Srikanth Vallabani et al.   Journal of Biomedical Nanotechnology

Zinc Oxide Nanoparticles Induce Oxidative Stress and Genotoxicity in Human Liver Cells (HepG2)

(2011) Vyom Sharma et al.   Journal of Biomedical Nanotechnology

Cytogenetic and genotoxic effects of zinc oxide nanoparticles on root cells of Allium cepa

(2011) Mamta Kumari et al.   JOURNAL OF HAZARDOUS MATERIALS

Interactions between Al12X (X = Al, C, N and P) nanoparticles and DNA nucleobases/base pairs: implications for nanotoxicity

(2011) Peng Jin et al.   JOURNAL OF MOLECULAR MODELING

Zinc Oxide Nanoparticle Induced Genotoxicity in Primary Human Epidermal Keratinocytes

(2011) Vyom Sharma et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

The role of COX-2 and Nrf2/ARE in anti-inflammation and antioxidative stress: Aging and anti-aging

(2011) Cheng Luo et al.   MEDICAL HYPOTHESES

Cytotoxic and genotoxic effects of multi-wall carbon nanotubes on human umbilical vein endothelial cells in vitro

(2011) Yuan-Yuan Guo et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Genotoxic effects of silver nanoparticles stimulated by oxidative stress in human normal bronchial epithelial (BEAS-2B) cells

(2011) Ha Ryong Kim et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Characterization of synthesized silver nanoparticles and assessment of its genotoxicity potentials using the alkaline comet assay

(2011) Natesan A.L. Flower et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Investigation on the genotoxicity of different sizes of gold nanoparticles administered to the lungs of rats

(2011) Markus Schulz et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Induction of oxidative stress, DNA damage and apoptosis in mouse liver after sub-acute oral exposure to zinc oxide nanoparticles

(2011) Vyom Sharma et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Titanium dioxide nanoparticles exhibit genotoxicity and impair DNA repair activity in A549 cells

(2011) Mary-Line Jugan et al.   Nanotoxicology

TiO2nanoparticles induce oxidative DNA damage and apoptosis in human liver cells

(2011) Ritesh K Shukla et al.   Nanotoxicology

Ameliorative Effects of Dimetylthiourea and N-Acetylcysteine on Nanoparticles Induced Cyto-Genotoxicity in Human Lung Cancer Cells-A549

(2011) Ritesh Kumar Srivastava et al.   PLoS One

Cytotoxic and genotoxic effects of silver nanoparticles in testicular cells

(2011) Nana Asare et al.   TOXICOLOGY

The comet assay in nanotoxicology research

(2010) Hanna L. Karlsson   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Toxicity assessment of nanomaterials: methods and challenges

(2010) Alok Dhawan et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Cytotoxicity of zinc oxide (ZnO) nanoparticles is influenced by cell density and culture format

(2010) Boon Chin Heng et al.   ARCHIVES OF TOXICOLOGY

Cytotoxicity and genotoxicity of silver nanoparticles in the human lung cancer cell line, A549

(2010) Rasmus Foldbjerg et al.   ARCHIVES OF TOXICOLOGY

DNA binding and aggregation by carbon nanoparticles

(2010) Hongjie An et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Nanosized titanium dioxide particles do not induce DNA damage in human peripheral blood lymphocytes

(2010) Stephan Hackenberg et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

p38 MAPK Activation, DNA Damage, Cell Cycle Arrest and Apoptosis As Mechanisms of Toxicity of Silver Nanoparticles in Jurkat T Cells

(2010) Hyun-Jeong Eom et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Comparative Cytotoxicity of Al2O3, CeO2, TiO2 and ZnO Nanoparticles to Human Lung Cells

(2010) In-Sun Kim et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

The in vitro genotoxicity of orthopaedic ceramic (Al2O3) and metal (CoCr alloy) particles

(2010) Aikaterini Tsaousi et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Intracellular synchrotron nanoimaging and DNA damage/genotoxicity screening of novel lanthanide-coated nanovectors

(2010) David J Lewis et al.   Nanomedicine

Genotoxicity and cytotoxicity of zinc oxide and titanium dioxide in HEp-2 cells

(2010) Ilham F Osman et al.   Nanomedicine

Nanotoxicology: no small matter

(2010) Neus Feliu et al.   Nanoscale

DNA damage and alterations in expression of DNA damage responsive genes induced by TiO2nanoparticles in human hepatoma HepG2 cells

(2010) Jana PetkoviĆ et al.   Nanotoxicology

ROS-mediated genotoxicity induced by titanium dioxide nanoparticles in human epidermal cells

(2010) Ritesh K. Shukla et al.   TOXICOLOGY IN VITRO

Silver nanoparticles: Evaluation of DNA damage, toxicity and functional impairment in human mesenchymal stem cells

(2010) Stephan Hackenberg et al.   TOXICOLOGY LETTERS

Synthesis of Fluorescent Carbohydrate-Protected Au Nanodots for Detection of Concanavalin A andEscherichia coli

(2009) Chih-Ching Huang et al.   ANALYTICAL CHEMISTRY

Silver nanospheres are cytotoxic and genotoxic to fish cells

(2009) John Pierce Wise Sr. et al.   AQUATIC TOXICOLOGY

Biodistribution and toxicity of intravenously administered silica nanoparticles in mice

(2009) Guangping Xie et al.   ARCHIVES OF TOXICOLOGY

NanoGenotoxicology: The DNA damaging potential of engineered nanomaterials

(2009) Neenu Singh et al.   BIOMATERIALS

Titanium Dioxide Nanoparticles Induce DNA Damage and Genetic Instability In vivo in Mice

(2009) B. Trouiller et al.   CANCER RESEARCH

Development ofin vitrosystems for nanotoxicology: methodological considerations

(2009) Vicki Stone et al.   CRITICAL REVIEWS IN TOXICOLOGY

Direct Combination of Nanoparticle Fabrication and Exposure to Lung Cell Cultures in a Closed Setup as a Method To Simulate Accidental Nanoparticle Exposure of Humans

(2009) Barbara Rothen-Rutishauser et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Photoinduced DNA Cleavage by α-, β-, and γ-Cyclodextrin-Bicapped C60Supramolecular Complexes

(2009) Deyan Wang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Genotoxic effects of nanosized and fine TiO2

(2009) GCM Falck et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Changing the dose metric for inhalation toxicity studies: Short-term study in rats with engineered aerosolized amorphous silica nanoparticles

(2009) Christie M. Sayes et al.   INHALATION TOXICOLOGY

On the challenge of quantifying man-made nanoparticles in the aquatic environment

(2009) Alan G. Howard   JOURNAL OF ENVIRONMENTAL MONITORING

Comparative study of the cytotoxic and genotoxic effects of titanium oxide and aluminium oxide nanoparticles in Chinese hamster ovary (CHO-K1) cells

(2009) A.L. Di Virgilio et al.   JOURNAL OF HAZARDOUS MATERIALS

Evaluation of genotoxicity of amine-terminated water-dispersible FePt nanoparticles in the Ames test and in vitro chromosomal aberration test

(2009) Shinya Maenosono et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Mutagenicity of water-soluble ZnO nanoparticles in Ames test

(2009) Rie Yoshida et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Induction of mesothelioma by a single intrascrotal administration of multi-wall carbon nanotube in intact male Fischer 344 rats

(2009) Yoshimitsu Sakamoto et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Effects of fullerenol C60(OH)24 on the frequency of micronuclei and chromosome aberrations in CHO-K1 cells

(2009) Jasminka Mrđanović et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Testing strategies for the safety of nanoparticles used in medical applications

(2009) Maria Dusinska et al.   Nanomedicine

Nanoceria have no genotoxic effect on human lens epithelial cells

(2009) Barbara K Pierscionek et al.   NANOTECHNOLOGY

Nanomaterials: A challenge for toxicologists

(2009) Alok Dhawan et al.   Nanotoxicology

The effect of zinc oxide and titanium dioxide nanoparticles in the Comet assay with UVA photoactivation of human sperm and lymphocytes

(2009) Rajendran C. Gopalan et al.   Nanotoxicology

Cytotoxicity and oxidative DNA damage by nanoparticles in human intestinal Caco-2 cells

(2009) Kirsten Gerloff et al.   Nanotoxicology

Genotoxic responses to titanium dioxide nanoparticles and fullerene in gpt delta transgenic MEF cells

(2009) An Xu et al.   Particle and Fibre Toxicology

Lung inflammation and genotoxicity following pulmonary exposure to nanoparticles in ApoE-/- mice

(2009) Nicklas Jacobsen et al.   Particle and Fibre Toxicology

Titanium dioxide nanoparticles induce oxidative stress and DNA-adduct formation but not DNA-breakage in human lung cells

(2009) Kunal Bhattacharya et al.   Particle and Fibre Toxicology

Surface Characteristics, Copper Release, and Toxicity of Nano- and Micrometer-Sized Copper and Copper(II) Oxide Particles: A Cross-Disciplinary Study

(2009) Klara Midander et al.   Small

Absence of Carcinogenic Response to Multiwall Carbon Nanotubes in a 2-Year Bioassay in the Peritoneal Cavity of the Rat

(2009) Julie Muller et al.   TOXICOLOGICAL SCIENCES

DNA damaging potential of zinc oxide nanoparticles in human epidermal cells

(2009) Vyom Sharma et al.   TOXICOLOGY LETTERS

In vitro and in vivo genotoxicity tests on fullerene C60 nanoparticles

(2009) Naohide Shinohara et al.   TOXICOLOGY LETTERS

Size-dependent toxicity of metal oxide particles—A comparison between nano- and micrometer size

(2009) Hanna L. Karlsson et al.   TOXICOLOGY LETTERS

Cytotoxicity and Genotoxicity of Silver Nanoparticles in Human Cells

(2008) P. V. AshaRani et al.   ACS Nano

Clastogenic and aneugenic effects of multi-wall carbon nanotubes in epithelial cells

(2008) Julie Muller et al.   CARCINOGENESIS

Copper Oxide Nanoparticles Are Highly Toxic: A Comparison between Metal Oxide Nanoparticles and Carbon Nanotubes

(2008) Hanna L. Karlsson et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Genotoxic and cytotoxic potential of titanium dioxide (TiO2) nanoparticles on fish cells in vitro

(2008) William F. Vevers et al.   ECOTOXICOLOGY

Environmental behavior and ecotoxicity of engineered nanoparticles to algae, plants, and fungi

(2008) Enrique Navarro et al.   ECOTOXICOLOGY

Titanium dioxide nanoparticles trigger p53-mediated damage response in peripheral blood lymphocytes

(2008) Su Jin Kang et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Oxidatively Damaged DNA in Rats Exposed by Oral Gavage to C 60 Fullerenes and Single-Walled Carbon Nanotubes

(2008) Janne K. Folkmann et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Chemical stability of metallic nanoparticles: A parameter controlling their potential cellular toxicity in vitro

(2008) Mélanie Auffan et al.   ENVIRONMENTAL POLLUTION

Twenty-Eight-Day Oral Toxicity, Genotoxicity, and Gender-Related Tissue Distribution of Silver Nanoparticles in Sprague-Dawley Rats

(2008) Yong Soon Kim et al.   INHALATION TOXICOLOGY

How Close Can You Get? Studies of Ultrafast Light-Induced Processes in Ruthenium-[60] Fullerene Dyads with Short Pyrazolino and Pyrrolidino Links

(2008) Susanne Karlsson et al.   INORGANIC CHEMISTRY

Comparative study of cytotoxicity, oxidative stress and genotoxicity induced by four typical nanomaterials: the role of particle size, shape and composition

(2008) Hui Yang et al.   JOURNAL OF APPLIED TOXICOLOGY

Induction of mesothelioma in p53+/− mouse by intraperitoneal application of multi-wall carbon nanotube

(2008) Atsuya Takagi et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Reproducible Comet Assay of Amorphous Silica Nanoparticles Detects No Genotoxicity

(2008) Clifford A. Barnes et al.   NANO LETTERS

A tale of opportunities, uncertainties, and risks

(2008) Paul J.A. Borm et al.   Nano Today

A multidisciplinary approach to the identification of reference materials for engineered nanoparticle toxicology

(2008) Robert J. Aitken et al.   Nanotoxicology

DNA damage response to different surface chemistry of silver nanoparticles in mammalian cells

(2008) Maqusood Ahamed et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Studies on the in vitro genotoxicity of baytubes®, agglomerates of engineered multi-walled carbon-nanotubes (MWCNT)

(2008) U. Wirnitzer et al.   TOXICOLOGY LETTERS

Multi-walled carbon nanotubes: Lack of mutagenic activity in the bacterial reverse mutation assay

(2008) Antonella Di Sotto et al.   TOXICOLOGY LETTERS