Combining in vitro embryotoxicity data with physiologically based kinetic (PBK) modelling to define in vivo dose–response curves for developmental toxicity of phenol in rat and human

Relative embryotoxic potency of p-substituted phenols in the embryonic stem cell test (EST) and comparison to their toxic potency in vivo and in the whole embryo culture (WEC) assay

(2012) Marije Strikwold et al.   TOXICOLOGY LETTERS

Prediction of Human Drug Clearance by Multiple Metabolic Pathways: Integration of Hepatic and Intestinal Microsomal and Cytosolic Data

(2011) H. E. Cubitt et al.   DRUG METABOLISM AND DISPOSITION

Tutorial on physiologically based kinetic modeling in molecular nutrition and food research

(2011) Ivonne M. C. M. Rietjens et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Development and evaluation of a harmonized physiologically based pharmacokinetic (PBPK) model for perchloroethylene toxicokinetics in mice, rats, and humans

(2011) Weihsueh A. Chiu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Metabolomic search for uremic toxins as indicators of the effect of an oral sorbent AST-120 by liquid chromatography/tandem mass spectrometry

(2010) Kaori Kikuchi et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

The Use of In Vitro Toxicity Data and Physiologically Based Kinetic Modeling to Predict Dose-Response Curves for In Vivo Developmental Toxicity of Glycol Ethers in Rat and Man

(2010) Jochem Louisse et al.   TOXICOLOGICAL SCIENCES

Relative Importance of Intestinal and Hepatic Glucuronidation—Impact on the Prediction of Drug Clearance

(2009) Helen E. Cubitt et al.   PHARMACEUTICAL RESEARCH

Formed and preformed metabolites: facts and comparisons

(2008) K. Sandy Pang et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY