Article
Microbiology
Mian Muhammad Salman, Muhammad Nawaz, Tahir Yaqub, Muhammad Hassan Mushtaq
Summary: The milk microbiota of Sahiwal cattle has been found to have significant impact on mastitis susceptibility, with higher microbial diversity in healthy cows and dominant taxa that may serve as signature microbes for mastitis susceptibility.
Article
Microbiology
Kang Xiao, Zhengyu Chen, Qin Long
Summary: Microbial communities on the ocular surface are important for maintaining homeostasis. This study investigated the changes in conjunctival microbiota associated with myopia. Swab specimens were collected from low myopia (LM) and high myopia (HM) patients. Analysis revealed distinct microbiome composition between the two groups, with higher abundances of Proteobacteria and lower abundances of Actinobacteria in the HM group. The levels of Acinetobacter were significantly higher in the HM group compared to the LM group. These findings suggest a bacterial microbiota imbalance in the conjunctival sac of HM patients.
JOURNAL OF MICROBIOLOGY
(2023)
Article
Microbiology
Simon O. Weiland, Matsapume Detcharoen, Birgit C. Schlick-Steiner, Florian M. Steiner
Summary: This study investigates the effects of tetracycline on fly locomotion, wing morphology, and gut microbiome using Drosophila nigrosparsa. The results show that antibiotic treatment does not affect fly locomotion after two generations of recovery, and restoring the gut microbiome can reduce potential side effects of tetracycline. It suggests the need for a general assessment of the direct and indirect effects of antibiotics after a specific recovery time.
Article
Microbiology
Carolina N. Resendiz-Nava, Hilda V. Silva-Rojas, Angel Rebollar-Alviter, Dulce M. Rivera-Pastrana, Edmundo M. Mercado-Silva, Gerardo M. Nava
Summary: This study analyzed the performance of 16S rRNA gene PCR primers and revealed the specificity and coverage of different primer sets. The results highlight the impact of taxonomy changes on molecular assays and data interpretation, emphasizing the urgent need to revise and update the molecular tools used for molecular microbial analyses.
Article
Biochemistry & Molecular Biology
Bianca R. P. Brown, Jacob R. Goheen, Seth D. Newsome, Robert M. Pringle, Todd M. Palmer, Leo M. Khasoha, Tyler R. Kartzinel
Summary: Analysing the gut microbiomes of 14 sympatric small mammal species in an African savanna, it was found that the differences in gut microbiomes were correlated with the phylogenetic relatedness of the hosts, with stronger patterns observed at deeper levels of the phylogeny. Additionally, the gut microbiome diversity and composition were also correlated with the body size, dietary breadth, and dietary overlap of the hosts.
Article
Environmental Sciences
Alexis Berger, Patricia Blackwelder, Tamara Frank, Tracey T. Sutton, Nina M. Pruzinsky, Natalie Slayden, Jose V. Lopez
Summary: This study identifies the bacterial bioluminescent symbionts of Pyrosoma atlanticum collected in the northern Gulf of Mexico using various methods, including light and electron microscopy, as well as molecular genetics. The research found that more than 50% of the bacterial taxa present in the tunicate samples were bioluminescent symbiotic bacteria Vibrionaceae. In addition, the study confirmed the presence of intracellular rod-like bacteria in the pyrosome light organs, suggesting bacteriocyte formation similar to other invertebrates.
FRONTIERS IN MARINE SCIENCE
(2021)
Article
Environmental Sciences
Guozhu Ye, Xu Zhang, Changzhou Yan, Yi Lin, Qiansheng Huang
Summary: The study utilized 16S rRNA gene sequencing to reveal polystyrene microplastics (PS)-induced microbial dysbiosis in surrounding seawater cultivating marine medaka, uncovering changes in microbial function. Eight bacterial taxa were identified as potential biomarkers for assessing microbial dysbiosis and metabolic responses in the surrounding seawater of marine medaka.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Biotechnology & Applied Microbiology
Valentina Serra, Leandro Gammuto, Giulio Petroni, Adriana Ciurli, Carolina Chiellini
Summary: This study investigates the interactions between microalgae and bacteria, focusing on the associations in the "phycosphere". The research identifies several bacterial strains associated with the Chlorella-like strain SEC_LI_ChL_1, highlighting their similar tolerance patterns and potential role in microalgal growth promotion and defense against environmental pollutants.
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS
(2022)
Article
Microbiology
Xiaowei Song, Jingwei Zhang, Jinghan Song, Yuanyuan Zhai
Summary: The study characterized the small intestine microbiota of hibernating Asiatic toads, identifying Pseudomonas as a key adaptor for the gut microbiota during hibernation. Both sex and host genetic background had minor effects on microbiota variation, while life stage was determined to be the decisive factor driving differences between populations. A large proportion of microbiota variation could not be explained by measured deterministic factors, suggesting other factors or stochastic processes play key roles in shaping gut bacterial community of hibernating amphibians.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Chenhui Yu, Qianqian Tu, Xiaoliu Huangfu, Yinying Zhu, Leilei Fan, Hainan Ai, Mei Chen, Qiang He
Summary: This study investigated the impact of hydraulic retention time (HRT) on nitrous oxide (N2O) production during nitrification in a BAF reactor. Results showed that the N2O production rate was highest at 4 hours HRT and lowest at 6 hours HRT, with a slight increase at 8 hours HRT. Internal biofilm microenvironment analysis and DNA analysis confirmed these findings.
ENVIRONMENTAL TECHNOLOGY & INNOVATION
(2021)
Article
Soil Science
Marineide Rodrigues Amorim, Lucas William Mendes, Jadson Emanuel Lopes Antunes, Louise Melo de Souza Oliveira, Vania Maria Maciel Melo, Francisca Andrea Silva Oliveira, Joao Pedro Alves Aquino, Sandra Mara Barbosa Rocha, Arthur Prudencio de Araujo Pereira, Antonio Felix da Costa, Jose de Paula Oliveira, Fabio Fernando Araujo, Marcia do Vale Barreto Figueiredo, Ademir Sergio Ferreira Araujo
Summary: The study found that the bacterial community structure and composition inside leguminous plant nodules differed from the bulk soil, but were not significantly different among sites. Cowpeas selected a specific bacterial group to colonize the nodules, regardless of soil properties.
APPLIED SOIL ECOLOGY
(2022)
Article
Medicine, Research & Experimental
Sukjung Choi, Jongsuk Chung, Mi-La Cho, Donghyun Park, Sun Shim Choi
Summary: This study analyzed microbiome compositions in tumor and normal tissues of CRC patients, and revealed that certain pathogenic bacteria were more abundant in tumor tissues. Additionally, bacteria associated with bacterial motility proteins and bile acid secretion pathways were enriched in tumor tissues. Interestingly, the abundance of pathogenic bacteria was positively correlated with the expression of host genes relevant to cell cycle and proliferation. Moreover, the presence of pathogenic bacteria was unexpectedly higher in nonrecurrent CRC patients compared to those with recurrence.
JOURNAL OF TRANSLATIONAL MEDICINE
(2021)
Article
Microbiology
Li Yuan, Wei Wang, Wei Zhang, Yan Zhang, Chong Wei, Jingnan Li, Daobin Zhou
Summary: The research found that the composition of gut microbiota in patients with diffuse large B cell lymphoma (DLBCL) significantly changed, showing different microbial diversity and composition compared to the control group. The intestinal microbiota in the DLBCL group exhibited a continuous evolutionary relationship, and functional prediction results indicated significant differences in metabolism and biosynthesis processes.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Ecology
Renata de Oliveira Aquino Zani, Milene Ferro, Mauricio Bacci Jr
Summary: This study found phylogenetically distinct diazotrophs in leaf-cutting ants, which integrate a symbiotic nutrition network and facilitate ant nutrition on nitrogen. Additionally, the strains identified in South American ants were genetically similar to those found in ants from other regions, indicating a wide geographic dispersion of these microorganisms.
ECOLOGY AND EVOLUTION
(2021)
Article
Agronomy
Andre May, Luciana Fontes Coelho, Alexandre Pedrinho, Bruna Durante Batista, Lucas William Mendes, Rodrigo Mendes, Marcelo Augusto Boechat Morandi, Gabriel Barth, Ronaldo Silva Viana, Elke Simoni Dias Vilela
Summary: In this study, the bacterial community in the shoot and rhizosphere of healthy soybean plants was characterized. The effects of these communities on seedling development were assessed by transplanting them to seeds. The results showed that the diversity of the bacterial consortium from the rhizosphere was higher than that from the shoot. However, the application of bacterial consortium in seedlings had no influence on diversity. The seedlings inoculated with the bacterial consortium showed an enrichment of plant growth-promoting groups and increased abundance of functions related to plant protection and nutrition.
ARCHIVES OF AGRONOMY AND SOIL SCIENCE
(2023)
Article
Information Science & Library Science
Muhammad Asif Naveed, Naveed Abbas Shah
Summary: This study examined the information literacy skills of lawyers in the District Bar Association of Sargodha, Punjab, Pakistan. The majority of lawyers had not received any formal training in information literacy, but recognized its importance for their workplace, especially legal research. The study also found that age, experience, computer proficiency, and English language skills predicted the levels of information literacy among lawyers.
JOURNAL OF LIBRARIANSHIP AND INFORMATION SCIENCE
(2023)
Article
Environmental Sciences
Zulqarnain Satti, Muhammad Naveed, Muhammad Shafeeque, Sikandar Ali, Farkhod Abdullaev, Tauseef Muhammad Ashraf, Muhammad Irshad, Lanhai Li
Summary: This study examines the seasonal and interannual variability of snow cover, vegetation, and land surface temperature (LST) in the Gilgit Baltistan region of northern Pakistan using MODIS datasets and observed data. The results show an increase in snow cover during winter but a significant decrease between June and July. There is a positive relationship between vegetation and LST, and a negative relationship between LST and snow cover, and vegetation and snow cover. The study also finds a decrease in snow cover at lower elevations and an increase at higher elevations.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Immunology
Hafiz Muzzammel Rehman, Muhammad Sajjad, Muhammad Akhtar Ali, Roquyya Gul, Muhammad Irfan, Muhammad Naveed, Munir Ahmad Bhinder, Muhammad Usman Ghani, Nadia Hussain, Amira S. A. Said, Amal H. I. Al Haddad, Mahjabeen Saleem
Summary: Zika virus (ZIKV) pandemic has posed serious threats to global health, and the search for effective drugs against the viral infection is urgent. Using in silico drug exploration, three potential drug molecules were identified as potent inhibitors of Zika NS2B-NS3 protease.
Article
Information Science & Library Science
Muhammad Asif Naveed, Haleema Saadia
Summary: This research investigated the development of information literacy skills and their self-perceived assessment among journalists in Pakistan. A total of 1089 responses were received through an online questionnaire survey in four Provinces and the Federal Capital of Pakistan. The majority of the surveyed journalists had received short-duration information literacy instruction during their careers, and perceived it as invaluable in their practical work context.
JOURNAL OF LIBRARIANSHIP AND INFORMATION SCIENCE
(2023)
Article
Biotechnology & Applied Microbiology
Muhammad Naveed, Muhammad Aqib Shabbir, Noor-ul Ain, Khushbakht Javed, Sarmad Mahmood, Tariq Aziz, Ayaz Ali Khan, Ghulam Nabi, Muhammad Shahzad, Mousa Essa Alharbi, Metab Alharbi, Abdulrahman Alshammari
Summary: The unexpected outbreak of monkeypox virus in 2022 has led researchers to focus on potential therapeutic approaches. This study used computational engineering to screen random antiviral compounds against the virulent protein MPXVgp169, and also modified toxic chains or atoms for enhanced efficacy. The chain-engineered dolutegravir showed promising results as a potential therapeutic strategy for monkeypox infection.
BIOENGINEERING-BASEL
(2023)
Article
Chemistry, Physical
Lubna Anjum Minhas, Abdul Samad Mumtaz, Muhammad Kaleem, Dunia Al Farraj, Khalid Kamal, Malik Aamer Hassan Minhas, Rooma Waqar, Rania M. Mahmoud
Summary: ZnONPs were synthesized using cyanobacteria and Nostoc sp. extract as a stabilizing, chelating, and reducing agent. XRD analysis confirmed the crystalline form and a mean crystalline size of 28.21 nm. SEM results showed the spherical shape of the biosynthesized nanoparticles. The synthesized zinc oxide NPs exhibited strong UV-vis absorption at 340 nm and showed promise in various biological applications such as antimicrobial activity, cytotoxicity, enzyme inhibition, and antioxidant activity.
Article
Materials Science, Multidisciplinary
Hussain Badshah, Surat Un Nisa, Mohammad Ajmal Ali, Mona S. Alwahibi, Asif Kamal, Muhammad Kaleem, Anwarzeb Khan, Shujaul Mulk Khan, Abdul Samad Mumtaz
Summary: The study investigated the heavy metal content in Morchella galilaea, a wild mushroom found in the irrigated plains of Charsadda, Pakistan. The results showed that the heavy metal levels in this mushroom were within permissible limits, posing no toxicological hazards to human health.
Article
Information Science & Library Science
Muhammad Asif Naveed, Rozeen Shaukat, Ali Asghar, Ghulam Murtaza Rafique
Summary: Through an online questionnaire, this research examined the effects of Covid-19 literacy on fear, protective behavior, and conspiracy beliefs of university students. The results indicated that Covid-19 literacy had negative effects on fear of Covid-19 and conspiracy beliefs, while positively influencing health-protective behaviors. These findings have practical implications for policymakers, NGOs, health professionals, and university librarians in planning health education and promotion.
JOURNAL OF ACADEMIC LIBRARIANSHIP
(2023)
Article
Education & Educational Research
Muhammad Asif Naveed, Javed Iqbal, Muhammad Zaheer Asghar, Rozeen Shaukat, Rabia Kishwer
Summary: This research explored the impact of information literacy on the creative skills of medical students, with a focus on the mediating role of lifelong learning. A cross-sectional survey was conducted among medical students from Khyber Pakhtunkhwa, Pakistan, using stratified convenient sampling. The results revealed that information literacy had both a direct and indirect positive influence on the creative skills of medical students, with lifelong learning mediating this relationship. These findings have implications for information literacy instruction in medical education, particularly in developing countries like Pakistan.
MEDICAL EDUCATION ONLINE
(2023)
Article
Biochemistry & Molecular Biology
Muhammad Naveed, Muhammad Aqib Shabbir, Tariq Aziz, Ayesha Saleem, Rida Naveed, Ayaz Ali Khan, Taqweem Ul Haq, Metab Alharbi, Abdulrahman Alsahammari, Abdullah F. Alasmari
Summary: In this study, a mercury reductase was extracted and studied using computational techniques to understand its structure, function, and interaction with mercury. The results showed that the enzyme is involved in the bioremediation of mercury.
ACTA BIOCHIMICA POLONICA
(2023)
Article
Biochemistry & Molecular Biology
Muhammad Naveed, Sarmad Mahmood, Tariq Aziz, Muhammad Hammad Arif, Urooj Ali, Faisal Nouroz, Christos Zacharis, Metab Alharbi, Abdulrahman Alshammari, Abdullah F. Alasmari
Summary: This study proposes an mRNA-based vaccine candidate against the Nipah virus using a reverse-vaccinology approach and immunoinformatics. The candidate shows high antigenicity, structural stability, and the ability to induce a prompt and stable immune response. It has the potential to eliminate the virus from the body and serves as a foundation for future trials.
ACTA BIOCHIMICA POLONICA
(2023)
Article
Biochemistry & Molecular Biology
Muhammad Naveed, Muhammad Aqib Shabbir, Tariq Aziz, Hafiz Muhammad Hurraira, Sayyeda Fatima Zaidi, Ramsha Athar, Hassan Anwer Chattha, Metab Alharbi, Abdulrahman Alsahammari, Abdullah F. Alasmari
Summary: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder that currently has no cure. Genome editing technology, specifically CRISPR-Cas9, shows promise as a potential solution for the development of new ALS treatments. Studies have demonstrated the accuracy and effectiveness of CRISPR-Cas9-guided RNAs in silencing genes related to ALS. Utilizing CRISPR-Cas9 at the molecular level offers hope for effective ALS treatment.
ACTA BIOCHIMICA POLONICA
(2023)
Article
Microbiology
Lubna Anjum Minhas, Muhammad Kaleem, Amber Jabeen, Nabi Ullah, Hafiz Muhammad Umer Farooqi, Asif Kamal, Farooq Inam, Abdulwahed Fahad Alrefaei, Mikhlid H. Almutairi, Abdul Samad Mumtaz
Summary: Nanoparticles, specifically silver nanoparticles synthesized via phyco-technology, have shown potential therapeutic applications. The unique cyanobacterial strain Nodularia haraviana has untapped potential in nanotechnology and offers valuable insights for future advancements in the field. The comprehensive research findings indicate the lesser toxicity and multifaceted applications of phyco-synthesized AgNPs.
Article
Environmental Sciences
Lubna Anjum Minhas, Muhammad Kaleem, Malik Abrar Hassan Minhas, Rooma Waqar, Dunia A. Al Farraj, Mona Abdullah Alsaigh, Hussain Badshah, Muhammad Haris, Abdul Samad Mumtaz
Summary: This study demonstrates the biogenic synthesis of iron oxide nanoparticles (FeONPs) and characterizes their properties. FeONPs show potential antibacterial, antifungal, and antioxidant activities, with significant cytotoxicity against Leishmania tropica promastigotes and brine shrimps. This research provides a foundation for the biomedical applications of FeONPs.
Article
Pharmacology & Pharmacy
M. Naveed, N. Ain, T. Aziz, I. Ali, M. Aqib Shabbir, K. Javed, M. Alharbi, A. Alshammari, A. F. Alasmari
Summary: This study aims to identify and optimize potential drug candidates against toxic shock syndrome caused by S. aureus by targeting the pathogenic toxin protein using chromones as lead compounds. Among the screened compounds, 7-G lucosyloxy-5-hydroxy-2-[2-(4-hydroxyphe-nyl) ethyl] chromone exhibited the highest binding affinity and favorable drug-like properties.
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
(2023)
