4.7 Article

Determination and Dissipation of Fipronil and Its Metabolites in Peanut and Soil

Journal

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Volume 63, Issue 18, Pages 4435-4443

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jf5054589

Keywords

fipronil; metabolites; peanut; residues; QuEChERS; LC-MS/MS

Funding

  1. National Natural Science Foundation of China [21177155]
  2. National Instrumentation Program of China from the Chinese Ministry of Science and Technology [2013YQ510391]

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In this study, a modified quick, easy, cheap, effective, rugged, and safe (QuEChERS) method was established for the extraction and cleanup of fipronil and its three metabolites (fipronil solfone, sulfide, and desulfinyl) in peanut kernel, shell, straw, seedling, and soil samples, and liquid chromatography-tandem mass spectrometry (LC-MS/MS) was used for analysis. The average recoveries were 66-116% at the level of 0.001-0.1 mg/kg with the RSD <19%, and the limit of detection was 0.3 ng/g for all matrices. The dissipation experiment results demonstrated that fipronil dissipated more rapidly in peanut seedling than in soil, with half-lives of <1 day in peanut seedling and 32-57 days in soil depending on the soil pH. The final residues at harvest of peanut kernels were all below 0.02 mg/kg, whereas in peanut shell and straw, the total highest residues were 0.99 and 0.30 mg/kg, respectively. Fipronil-desulfinyl and fipronil-sulfone were the highest residue metabolites in peanut plant (seedling and straw) and soil samples, respectively.

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