Article
Biotechnology & Applied Microbiology
Golam Rbbani, Artem Nedoluzhko, Prabhugouda Siriyappagouder, Fedor Sharko, Jorge Galindo-Villegas, Joost A. M. Raeymaekers, Rajesh Joshi, Jorge M. O. Fernandes
Summary: This study used an integrative omics approach to identify myogenic circular RNAs (circRNAs) in Nile tilapia, and found 1947 mRNAs, 9 miRNAs, and 4 circRNAs that were differentially expressed between fast- and slow-growing individuals. These miRNAs can regulate myogenic genes and have binding sites for the novel circRNA circMef2c. The study suggests that circ-Mef2c may interact with three miRNAs and 65 differentially expressed mRNAs to form multiple competing endogenous RNA networks that regulate growth, providing new insights into the role of circRNAs in muscle growth regulation in teleosts.
Article
Biochemistry & Molecular Biology
Xianhui Ruan, Minghui Cao, Wei Yan, Ying Z. Jones, Asa B. Gustafsson, Hemal H. Patel, Simon Schenk, Shizhen Emily Wang
Summary: Extracellular vesicles secreted by breast cancer cells impair skeletal muscle mitochondrial homeostasis and function through the transfer of miR-122-5p to myocytes, leading to decreased mitochondrial content and energy production and increased oxidative stress. Restoring Tp53 in muscle can abolish mitochondrial myopathology and partially rescue impaired running capacity in mice carrying breast tumors. These findings suggest that breast cancer cell-derived extracellular vesicles mediate skeletal muscle mitochondrial dysfunction, contributing to muscle weakness in cancer patients.
Article
Environmental Sciences
Mohamed F. A. Elazab, Abdelgayed M. Younes, Alkhateib Y. Gaafar, Alaa Z. Abu-Bryka, Mohamed M. Abdel-Daim
Summary: The immune-suppressed model of Nile tilapia can be induced by intraperitoneal injection of Cyclophosphamide at a dosage of 200 mg/kg BW, leading to significant decreases in various immune-related parameters.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Fisheries
Aldo Felipe Fava, Gildete de Souza Bezerra, Dacley Hertes Neu, Fabio Bittencourt, Altevir Signor, Kerolay Valadao Carvalho, Ricacio Luan Marques Gomes, Wilson Rogerio Boscolo
Summary: This study assessed the feeding frequency for tilapia fingerlings and found that feeding 5 to 6 times a day resulted in better zootechnical performance and partial revenue.
AQUACULTURE NUTRITION
(2022)
Article
Fisheries
You Wu, Tengfei Wu, Lanying Yang, Yun Su, Chenhua Zhao, Lu Li, Jing Cai, Xiangyan Dai, Deshou Wang, Linyan Zhou
Summary: This study provides the first evidence that mstn gene mutation may promote the generation of a new fast-growing male strain of Nile tilapia.
Review
Endocrinology & Metabolism
Wataru Aoi, Yuko Tanimura
Summary: This passage highlights the importance of muscle-derived exosomes in regulating target protein expression and activity associated with metabolism and immune function. It also discusses the altered levels of circulating exosomes and their contents in muscle disorders and metabolic-related states, suggesting their potential as biomarkers.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Genetics & Heredity
Xuanze Ling, Qifan Wang, Pengfei Wu, Kaizhi Zhou, Jin Zhang, Genxi Zhang
Summary: This study investigated the potential target genes of miR-24-3p in chicken skeletal muscle. By using RNA-seq, the researchers identified differentially expressed genes and important biological processes and pathways associated with miR-24-3p. Furthermore, they validated the sequencing results through qPCR experiments. These findings have implications for understanding the regulatory role of miR-24-3p in chicken skeletal muscle and provide new directions for broiler breeding research.
Article
Fisheries
Filipe Chagas Teodozio de Araujo, Ricardo Pereira Ribeiro, Eric Costa Campos, Humberto Todesco, Karla Miky Tsujii, Lais Santana Celestino Mantovani, Rodrigo Feuerharmel Ribeiro, Jonathan Coimbra Carvalho, Jaisa Casetta, Nelson Mauricio Lopera-Barrero, Eliane Gasparino, Carlos Antonio Lopes de Oliveira
Summary: This study investigated the use of blood glucose as a selection criterion to enhance the adaptation of fish to the farming environment. The study found that blood glucose has sufficient genetic variability and is positively correlated with live weight, making it a suitable indicator for selecting fish. Additionally, the fish with high Estimated Breeding Value (EBV) for blood glucose demonstrated better adaptation to handling stress.
Article
Medicine, Research & Experimental
Anna Creismeas, Claire Gazaille, Audrey Bourdon, Marc-Antoine Lallemand, Virginie Francois, Marine Allais, Mireille Ledevin, Thibaut Larcher, Gilles Toumaniantz, Aude Lafoux, Corinne Huchet, Ignacio Anegon, Oumeya Adjali, Caroline Le Guiner, Bodvael Fraysse
Summary: Duchenne muscular dystrophy is a genetic disease caused by mutations in the dystrophin gene, leading to muscle wasting. This study suggests that TRPC1 and TRPC3 calcium channels may be potential therapeutic targets for treating DMD, as they are involved in calcium homeostasis alterations. Targeting TRPC3 channel expression and activity could be a promising approach for DMD treatment.
JOURNAL OF TRANSLATIONAL MEDICINE
(2021)
Article
Cell Biology
Ali Ali, Walaa M. Shaalan, Rafet Al-Tobasei, Mohamed Salem
Summary: The study investigates the molecular mechanisms of muscle atrophy and compensatory growth in Nile tilapia through transcriptome profiling. It identifies genes involved in muscle atrophy, such as those related to the ubiquitin-proteasome and autophagy/lysosome systems. It also reveals genes promoting muscle hypertrophy and microRNAs associated with muscle recovery. The findings provide insights into muscle mass regulation and can be used in breeding programs and future mechanistic studies.
Article
Cell Biology
Donato A. Rivas, Fei Peng, Townsend Benard, Adelino Sanchez Ramos da Silva, Roger A. Fielding, Lee M. Margolis
Summary: The study found that miR-19b-3p plays a crucial role in regulating muscle synthesis, contributing to understanding the varied responses of mobility-limited older adults to anabolic stimuli.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Md Fazle Rohani, Asma Akter Bristy, Jabed Hasan, Md Kabir Hossain, Md Shahjahan
Summary: The experiment found that the addition of zinc, vitamin E or both in the diet significantly improved growth parameters and feed utilization in Nile tilapia. Blood biochemical parameters showed no significant change among different groups, while muscle morphology notably improved in fish fed with supplemented diets.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2022)
Article
Fisheries
Eman Zahran, Engy Risha, Awad Rizk
Summary: The study found that propofol has longer induction and anesthesia duration compared to eugenol in fish anesthesia, while also having a faster recovery rate. In terms of hematological indices, the propofol group showed a transient increase compared to the eugenol group. However, there were no significant changes in other indicators such as leukocytic counts between the two groups. During anesthesia, both propofol and eugenol groups showed a temporary increase in glucose and cortisol levels, which returned to baseline levels during the recovery period.
Article
Fisheries
Eman Zahran, Fatma Abdelhamid, Eman Aboelfadl, Mansour El-Matbouli
Summary: This study evaluated general health indicators at the cellular and molecular levels in cultured Nile tilapia using wastewater effluents as the water source at different sites. Results showed a significant impact of wastewater on the fish, especially in those from highly polluted sites, with notable changes in pathological and biochemical parameters.
AQUACULTURE RESEARCH
(2021)
Article
Biochemistry & Molecular Biology
Yanhong Li, Jie Wang, Mauricio A. Elzo, Mingchuan Gan, Tao Tang, Jiahao Shao, Tianfu Lai, Yuan Ma, Xianbo Jia, Songjia Lai
Summary: Through experiments, it was found that in rabbits induced to be obese by a high-fat diet, there were significant differences in the expression of certain miRNAs and core genes, with the miRNAs being able to regulate transcription factors that impact lipid metabolism. These results contribute to a better understanding of the molecular mechanisms of skeletal muscle metabolism in rabbits.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Biotechnology & Applied Microbiology
Jintao Guo, Jiankun Huang, Ying Zhou, Yulin Zhou, Liying Yu, Huili Li, Lingyun Hou, Liuwei Zhu, Dandan Ge, Yuanyuan Zeng, Bayasi Guleng, Qiyuan Li
Article
Biochemistry & Molecular Biology
Biao Yan, Jin-Tao Guo, Li-Hui Zhao, Jin-Liang Zhao
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2012)
Article
Biochemistry & Molecular Biology
Biao Yan, Li-Hui Zhao, Jin-Tao Guo, Jin-Liang Zhao
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2012)
Review
Biotechnology & Applied Microbiology
Biao Yan, Zhen-Hua Wang, Jin-Tao Guo
Article
Biology
Biao Yan, Chang-Dong Zhu, Jin-Tao Guo, Li-Hui Zhao, Jin-Liang Zhao
JOURNAL OF EXPERIMENTAL BIOLOGY
(2013)
Article
Biology
Biao Yan, Jin-Tao Guo, Chang-dong Zhu, Li-Hui Zhao, Jin-Liang Zhao
JOURNAL OF EXPERIMENTAL BIOLOGY
(2013)
Article
Biochemistry & Molecular Biology
Biao Yan, Zhen-Hua Wang, Chang-Dong Zhu, Jin-Tao Guo, Jin-Liang Zhao
MOLECULAR BIOLOGY REPORTS
(2014)
Article
Medicine, General & Internal
Ke Liu, Jintao Guo, Kuai Liu, Peiyang Fan, Yuanyuan Zeng, Chaoqun Xu, Jiaxin Zhong, Qiyuan Li, Ying Zhou
Article
Oncology
Wenzhi Li, Chaoqun Xu, Jintao Guo, Ke Liu, Yudi Hu, Dan Wu, Hongkun Fang, Yun Zou, Ziwei Wei, Zhong Wang, Ying Zhou, Qiyuan Li
FRONTIERS IN ONCOLOGY
(2020)
Article
Genetics & Heredity
Qiyuan Li, Yuanyuan Zeng, Janet Wang, Hongkun Fang, Jintao Guo, Liying Yu, Taoling Zhong, Chaoqun Xu, Matthew Freedman, Thomas LaFramboise
Summary: In this study, allelic imbalance in tumors was evaluated in different cancer types, identifying a set of SNP loci with tumor allele specificity. These SNPs showed consistently different frequencies in cancer population compared to healthy population, enriched for predicted protein-damaging variants. Genes harboring these SNPs were found to be enriched for cancer-related biological processes and more likely to be essential in cancer cells.
BMC MEDICAL GENOMICS
(2021)
Article
Oncology
Jintao Guo, Ying Zhou, Chaoqun Xu, Qinwei Chen, Zsofia Sztupinszki, Judit Borcsok, Canqiang Xu, Feng Ye, Weiwei Tang, Jiapeng Kang, Lu Yang, Jiaxin Zhong, Taoling Zhong, Tianhui Hu, Rongshan Yu, Zoltan Szallasi, Xianming Deng, Qiyuan Li
Summary: The study identified a quantitative trait, mutational propensity (MP), and introduced an integrated method to infer genetic determinants of variations in the mutational processes in cancer patients. It was found that the genetic determinants of the somatic mutational processes in cancer provide complementary information to known cancer driver genes, clonal evolution, and clinical biomarkers.
Article
Oncology
Yudi Hu, Chaoqun Xu, Jun Ren, Yuanyuan Zeng, Fengyang Cao, Hongkun Fang, Guo Jintao, Ying Zhou, Qiyuan Li
Summary: In this study, we systematically investigated the impact of smoking on T cells in treatment naive NSCLC patients by integrating single-cell RNA-seq and bulk RNA-seq data. We identified a smoking-induced tumor specific Treg subset that actively interacts with exhausted T cells. These findings not only explained the effect of smoking on the tumor immune environment, but also provided new targets and biomarkers for precision immunotherapy of lung cancer.
TRANSLATIONAL ONCOLOGY
(2022)
Article
Medicine, Research & Experimental
Wei Shao, Zulfikar Azam, Jintao Guo, Shing Shun Tony To
Summary: The present study demonstrates the importance of PIK3CD in the progression of glioblastoma (GBM). By using CRISPR/Cas9 to knockout PIK3CD expression in GBM cells, the authors show that GBM migration, invasion, proliferation, and growth are greatly affected. Mechanistically, PIK3CD regulates the activity of PAK3 and PLEK2 through the axonogenesis pathway. PIK3CD depletion may serve as a potential prognostic factor and therapeutic target for GBM patients.
LABORATORY INVESTIGATION
(2022)
Article
Fisheries
Hunter S. Bailey, Ashley N. Fincannon, Lee A. Fuiman
Summary: This study investigated the transfer of fatty acids from broodstock diets to eggs and the time needed for the eggs to equilibrate to the diet in Southern flounder. The findings indicate that different diet treatments significantly affect the fatty acid composition of eggs, and it takes 8-16 weeks for the eggs to adapt to changes in the adult diet. These results are important for improving broodstock diets and feeding protocols in stock-enhancement programs.
Article
Fisheries
Yu Liu, Mingtao Lei, Hector Victor, Yan Wang
Summary: This study confirms the feasibility of replacing raw fish diet with a formulated diet in commercial farming of large yellow croaker, which can increase fish survival and yield, and reduce feed cost and body lipid deposition.
Article
Fisheries
Xiaoyan Zhang, Lize San, Yucong Yang, Yuehong Tao, Jiangong Ren, Yufeng Liu, Zhongwei He, Jiashuo Di, Ziteng Pei, Guixing Wang, Jilun Hou
Summary: Gynogenesis is an effective technique for establishing homogeneous lines and confirming potential chromosomal mechanisms of sex determination in fish. This study successfully induced gynogenetic families in Thamnaconus modestus and established a complete method for gynogenesis induction.
Article
Fisheries
Julieta C. Martinelli, Megan Considine, Helen R. Casendino, Carolyn M. Tarpey, Isadora Jimenez-Hidalgo, Jacqueline L. Padilla-Gamino, Teri L. King, Lorenz Hauser, Steven Rumrill, Chelsea L. Wood
Summary: Shell-boring polychaetes have caused significant damage to mariculture operations worldwide, particularly in the US Pacific region. This study provides a comprehensive dataset on the prevalence, species distribution, and environmental associations of these parasites, highlighting the impact of season, culturing methods, and environmental factors on infestation.
Article
Fisheries
Juan Gao, Xueshan Li, Kangle Lu, Kai Song, Jian Zhang, Ling Wang, Chunxiao Zhang
Summary: This study investigated the effects of dietary protein levels on growth performance, antioxidant capacity, digestive enzyme activity, and metamorphosis rate of bullfrog tadpoles. The optimal dietary protein level for bullfrog tadpoles was estimated to be 42.49%-46.50% of the diet.
Article
Fisheries
Qiang Li, Lijun Duan, Dongsheng Jin, Yuxin Chen, Yirong Lou, Qianjin Zhou, Zhongjie Xu, Fangjie Chen, Hongxian Chen, Guizong Xu, Maocang Yan, Guanjun Yang, Jianfei Lu, Yanjun Zhang, Jiong Chen
Summary: This study developed a centrifugal microfluidic chip with on-chip RPA to detect five pathogenic microorganisms. The chip enabled the parallel analysis of six genetic markers from a single sample and allowed for the highly automated detection of multiple samples. Compared with PCR and DNA sequencing, the on-chip RPA assay showed high sensitivity and specificity for detecting multiple pathogens in shrimp aquaculture.
Article
Fisheries
Xingchen Huo, Pengxu Wang, Fengxia Zhao, Qian Liu, Qingqing Tian, Lingjie Tang, Maolin Lv, Zhaohui Wei, Chunrong Yang, Jianguo Su
Summary: Bacterial diseases in aquaculture ponds have negative effects on sustainable development. The use of composite I20 biotherapy has been shown to effectively treat bacterial diseases in bullfrog ponds, providing a new strategy for controlling bacterial diseases in aquaculture.
Article
Fisheries
Peng Yin, Takaya Saito, Per Gunnar Fjelldal, Bjorn Tharandur Bjornsson, Sofie Charlotte Remo, Sandeep Sharma, Rolf Erik Olsen, Kristin Hamre
Summary: This study aims to investigate the effect of seasonal changes in temperature and photoperiod on the redox metabolism of Atlantic salmon at the molecular level. The research findings suggest that the changing photoperiod and temperature influenced the redox metabolism of Atlantic salmon, highlighting the importance of oxidative status in the ecological implications.
Article
Fisheries
Nicholas Oppong Mensah, Jeffery Kofi Asare, Emmanuel Tetteh-Doku Mensah, Ernest Christlieb Amrago, Frank Osei Tutu, Anthony Donkor
Summary: This study investigates aquaculture farmers' preference for climate-smart aquaculture insurance products, the challenges they face, and their preferred insurance coverage. The results show that farmers prefer Climate-Induced Aquaculture Stock Mortality Insurance and the most significant constraint is the delay in claim settlement.
Article
Fisheries
Qiu-Ping Chai, Pei Wu, Wei-Dan Jiang, Yang Liu, Hong-Mei Ren, Xiao-Wan Jin, Lin Feng, Xiao-Qiu Zhou
Summary: The study found that appropriate levels of potassium diformate (KDF) can enhance the immune defense and mediate the inflammatory process in fish, possibly through the regulation of T cell differentiation via JAK-STAT and NF-kappa B signaling pathways.
Article
Fisheries
Tian Zhu, Haomin Jia, Haopeng Zhang, Yujing Xiao, Cui Han, Jiaxin Yang
Summary: Chicken manure has significant effects on the cultivation of Chlorella and rotifers. The optimal amount of chicken manure extract for continuous cultivation is 10 mLL-1. Chicken manure can promote the growth of Chlorella and improve the fatty acid composition, indirectly enhancing the growth condition and fatty acid content of rotifers.
Article
Fisheries
Zheng Luo, Yang Yu, Zhenning Bao, Fuhua Li
Summary: This study analyzed the heritability and genetic correlation of two growth traits in Pacific white shrimp and evaluated the genomic prediction using different genomic selection models. The results showed that the NeuralNet model had the highest prediction accuracy and better prospects for predicting shrimp growth traits.
Article
Fisheries
Alberto Ruiz, Ignasi Sanahuja, Karl B. Andree, Dolors Furones, Paul G. Holhorea, Josep A. Calduch-Giner, Jose J. Pastor, Marc Vinas, Jaume Perez-Sanchez, Sofia Morais, Enric Gisbert
Summary: Supplementing diets with a combination of spice oleoresins can reduce lipid accumulation and inflammation in farmed fish. The combination of spice oleoresins also has an immunomodulatory effect on the fish's intestinal immune system, potentially offering anti-inflammatory benefits.
Article
Fisheries
Beibei Zhao, Renhui Mei, Le Li, Di Hu, Lei Li
Summary: This study reveals that JfCXCL8_L1a and JfCXCL8_L1b have different immune pathways, and JfCXCL8_L1b plays a significant role in enhancing the adaptive immunity of T cell-dependent antigen.
Article
Fisheries
Yuhang Liu, Danying Cao, Nan Wu, Xuyang Zhao, Qingsong Zhu, Lian Su, Fatima Altaf, Qianqian Zhang, Haokun Liu, Yongming Li, Bruno Hamish Unger, Yingyin Cheng, Wanting Zhang, Aihua Li, Yaping Wang, Xiao-Qin Xia
Summary: Based on previous research, sinomenine has been found to protect mucosal immunity in farmed fish species by preventing intestinal pathological changes and regulating gene expression related to inflammation. It also enhances immune homeostasis and controls the growth of pathogenic bacteria.
