TRPC3, but not TRPC1, as a good therapeutic target for standalone or complementary treatment of DMD

Contribution of TRPC Channels to Intracellular Ca2 + Dyshomeostasis in Smooth Muscle From mdx Mice

(2020) Jose R. Lopez et al.   Frontiers in Physiology

Post-Translational Modification and Natural Mutation of TRPC Channels

(2020) Xianji Liu et al.   Cells

Transient Receptor Potential Cation Channels and Calcium Dyshomeostasis in a Mouse Model Relevant to Malignant Hyperthermia

(2020) Jose Rafael Lopez et al.   ANESTHESIOLOGY

Assessment of Systemic Delivery of rAAVrh74.MHCK7.micro-dystrophin in Children With Duchenne Muscular Dystrophy

(2020) Jerry R. Mendell et al.   JAMA Neurology

Human Brain Region-Specific Alternative Splicing of TRPC3, the Type 3 Canonical Transient Receptor Potential Non-Selective Cation Channel

(2019) Jennie M. E. Cederholm et al.   CEREBELLUM

Therapeutic developments for Duchenne muscular dystrophy

(2019) Ingrid E. C. Verhaart et al.   Nature Reviews Neurology

TRP channels in cardiac and intestinal fibrosis

(2018) Ryuji Inoue et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Ca 2+ handling abnormalities in early-onset muscle diseases: Novel concepts and perspectives

(2017) Susan Treves et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Long-term microdystrophin gene therapy is effective in a canine model of Duchenne muscular dystrophy

(2017) Caroline Le Guiner et al.   Nature Communications

The golden retriever model of Duchenne muscular dystrophy

(2017) Joe N. Kornegay   Skeletal Muscle

Transient Receptor Potential Canonical (TRPC)/Orai1-dependent Store-operated Ca2+Channels

(2016) Jessica Sabourin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Validation of ultrasonography for non-invasive assessment of diaphragm function in muscular dystrophy

(2016) Nicholas P. Whitehead et al.   JOURNAL OF PHYSIOLOGY-LONDON

Absence of Dystrophin Disrupts Skeletal Muscle Signaling: Roles of Ca2+, Reactive Oxygen Species, and Nitric Oxide in the Development of Muscular Dystrophy

(2016) David G. Allen et al.   PHYSIOLOGICAL REVIEWS

Practical utilization of recombinant AAV vector reference standards: focus on vector genomes titration by free ITR qPCR

(2016) Susan D'Costa et al.   Molecular Therapy-Methods & Clinical Development

Malignant hyperthermia: a review

(2015) Henry Rosenberg et al.   Orphanet Journal of Rare Diseases

Heteromeric TRPC3 with TRPC1 formed via its ankyrin repeats regulates the resting cytosolic Ca2+ levels in skeletal muscle

(2014) Jin Seok Woo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Trafficking mechanisms and regulation of TRPC channels

(2014) Lorena Brito de Souza et al.   CELL CALCIUM

Characterization of Dystrophin Deficient Rats: A New Model for Duchenne Muscular Dystrophy

(2014) Thibaut Larcher et al.   PLoS One

Involvement of TRPV2 and SOCE in calcium influx disorder in DMD primary human myotubes with a specific contribution of α1-syntrophin and PLC/PKC in SOCE regulation

(2013) Rania Harisseh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The mdx mouse model as a surrogate for Duchenne muscular dystrophy

(2013) Terence A. Partridge   FEBS Journal

Report of MDA muscle disease symposium on newborn screening for Duchenne muscular dystrophy

(2013) Jerry R. Mendell et al.   MUSCLE & NERVE

Isometric and Eccentric Force Generation Assessment of Skeletal Muscles Isolated from Murine Models of Muscular Dystrophies

(2013) Catherine Moorwood et al.   Jove-Journal of Visualized Experiments

Novel pyrazole compounds for pharmacological discrimination between receptor-operated and store-operated Ca2+entry pathways

(2012) H Schleifer et al.   BRITISH JOURNAL OF PHARMACOLOGY

TRP channels in normal and dystrophic skeletal muscle

(2012) Philippe Gailly   CURRENT OPINION IN PHARMACOLOGY

Alternative Splicing of the TRPC3 Ion Channel Calmodulin/IP3 Receptor-Binding Domain in the Hindbrain Enhances Cation Flux

(2012) Y. Kim et al.   JOURNAL OF NEUROSCIENCE

Delivery of AAV2/9-Microdystrophin Genes Incorporating Helix 1 of the Coiled-Coil Motif in the C-Terminal Domain of Dystrophin Improves Muscle Pathology and Restores the Level of α1-Syntrophin and α-Dystrobrevin in Skeletal Muscles of mdx Mice

(2011) Taeyoung Koo et al.   HUMAN GENE THERAPY

Expression and association of TRPC1 with TRPC3 during skeletal myogenesis

(2011) Kwok-Kuen Cheung et al.   MUSCLE & NERVE

TRPC1: Subcellular Localization?: Fig. 1.

(2010) Nicolas Tajeddine et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Malignant Hyperthermia and Muscular Dystrophies

(2009) Harshad Gurnaney et al.   ANESTHESIA AND ANALGESIA

Transient Receptor Potential Canonical Type 1 (TRPC1) Operates as a Sarcoplasmic Reticulum Calcium Leak Channel in Skeletal Muscle

(2009) Céline Berbey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calcium influx is sufficient to induce muscular dystrophy through a TRPC-dependent mechanism

(2009) Douglas P. Millay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myonuclear domain size and myosin isoform expression in muscle fibres from mammals representing a 100 000-fold difference in body size

(2008) Jing-Xia Liu et al.   EXPERIMENTAL PHYSIOLOGY

TRPC1 binds to caveolin-3 and is regulated by Src kinase - role in Duchenne muscular dystrophy

(2008) O. L. Gervasio et al.   JOURNAL OF CELL SCIENCE

Codon and mRNA Sequence Optimization of Microdystrophin Transgenes Improves Expression and Physiological Outcome in Dystrophic mdx Mice Following AAV2/8 Gene Transfer

(2008) Helen Foster et al.   MOLECULAR THERAPY

Analysis of AAV Serotypes 1–9 Mediated Gene Expression and Tropism in Mice After Systemic Injection

(2008) Carmela Zincarelli et al.   MOLECULAR THERAPY